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Creatine Kinase MM Active Protein | CKMM active protein

Creatine Kinase MM (CK-MM), Human Heart

Gene Names
CKM; CKMM; M-CK
Synonyms
Creatine Kinase MM; Creatine Kinase MM (CK-MM); Human Heart; CK-MM; Human Heart - Lyophilized; CKMM active protein
Ordering
Form/Format
Lyophilized
Sequence Length
381
Source
Human Heart
EC Number
2.7.3.2
Unit Definition
One unit will catalyze the transphosphorylation of one micromole of phosphate from creatine phosphate to ADP per minute at 37 degree C.
Specific Activity
> 400 U/mg protein
Protein
> 0.5 mg protein/mg (Coomassie)
CK Electrophoresis
100% CK-MM, no CK-MB or CK-BB detected
CAS Number
9001-15-4
Activity
> 200 U/mg (Dimension Clinical Chemistry System)
Preparation and Storage
At -20 degree C
Related Product Information for CKMM active protein
MyBioSource is the leading manufacturer of human Creatine Kinase MM (CK-MM) isoenzyme for medical research and manufacturing.

Custom preparations, technical support, bulk quantities and aliquoting available.

We are able to supply cardiac markers such as human CK-MB, Troponins I, T, C and Complex, both native and recombinant. In addition, we can provide gram quantities of high purity C-Reactive Protein (CRP) and Myoglobin, for your cardiac marker requirements.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,101 Da
NCBI Official Full Name
creatine kinase M-type
NCBI Official Synonym Full Names
creatine kinase, muscle
NCBI Official Symbol
CKM
NCBI Official Synonym Symbols
CKMM; M-CK
NCBI Protein Information
creatine kinase M-type; creatine kinase M chain
UniProt Protein Name
Creatine kinase M-type
UniProt Gene Name
CKM
UniProt Synonym Gene Names
CKMM
UniProt Entry Name
KCRM_HUMAN

NCBI Description

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

Uniprot Description

CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: EC 2.7.3.2; Kinase, other; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytosol

Molecular Function: creatine kinase activity; ATP binding

Biological Process: phosphocreatine biosynthetic process; phosphorylation; creatine metabolic process

Research Articles on CKMM

Similar Products

Product Notes

The CKMM ckm (Catalog #AAA173057) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Creatine Kinase MM, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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