Cytoskeleton-associated protein 5 (Ckap5) Recombinant Protein | Ckap5 recombinant protein

Recombinant Mouse Cytoskeleton-associated protein 5 (Ckap5) , partial

• Gene Names: Ckap5; T25636; mKIAA0097; 3110043H24Rik; 4930432B04Rik; D730027C18Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cytoskeleton-associated protein 5 (Ckap5); Recombinant Mouse Cytoskeleton-associated protein 5 (Ckap5); partial; Ckap5 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 2,011

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

SDS_PAGE

NCBI and Uniprot Product Information

• NCBI GI #: 260166719
• NCBI GeneID: 75786
• NCBI Accession #: NP_083713.2
• NCBI GenBank Nucleotide #: NM_029437.2
• UniProt Accession #: A2AGT5; Q0VGR0; Q3TML9; Q3UDY6; Q4VAE7; Q9CUN0; A0PJ77; A2AGT6; B2RRC4
• Molecular Weight: 223,518 Da
• NCBI Official Full Name: cytoskeleton-associated protein 5 isoform 2
• NCBI Official Synonym Full Names: cytoskeleton associated protein 5
• NCBI Official Symbol: Ckap5
• NCBI Official Synonym Symbols: T25636; mKIAA0097; 3110043H24Rik; 4930432B04Rik; D730027C18Rik
• NCBI Protein Information: cytoskeleton-associated protein 5
• UniProt Protein Name: Cytoskeleton-associated protein 5
• Protein Family: Cytoskeleton-associated protein
• UniProt Gene Name: Ckap5

Uniprot Description

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension. Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments.