Neuronal acetylcholine receptor subunit beta-2 (Chrnb2) Recombinant Protein | Chrnb2 recombinant protein
Recombinant Rat Neuronal acetylcholine receptor subunit beta-2 (Chrnb2)
NCBI and Uniprot Product Information
NCBI Description
co-assembles with the alpha 7 subunit to form a functional heteromeric nicotinic acetylcholine receptor [RGD, Feb 2006]
Uniprot Description
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subunit structure: Neuronal AChR is composed of two different types of subunits: alpha and beta. Beta-2 subunit can be combined to alpha-2, alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly
By similarity.
Subcellular location: Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in most regions of the CNS.
Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily. [View classification]
Research Articles on Chrnb2
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Product Notes
The Chrnb2 chrnb2 (Catalog #AAA966351) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-500. The amino acid sequence is listed below: TDTEERLVEH LLDPSRYNKL IRPATNGSEL VTVQLMVSLA QLISVHEREQ IMTTNVWLTQ EWEDYRLTWK PEDFDNMKKV RLPSKHIWLP DVVLYNNADG MYEVSFYSNA VVSYDGSIFW LPPAIYKSAC KIEVKHFPFD QQNCTMKFRS WTYDRTEIDL VLKSDVASLD DFTPSGEWDI IALPGRRNEN PDDSTYVDIT YDFIIRRKPL FYTINLIIPC VLITSLAILV FYLPSDCGEK MTLCISVLLA LTVFLLLISK IVPPTSLDVP LVGKYLMFTM VLVTFSIVTS VCVLNVHHRS PTTHTMAPWV KVVFLEKLPT LLFLQQPRHR CARQRLRLRR RQREREGAGA LFFREGPAAD PCTCFVNPAS VQGLAGAFRA EPTAAGPGRS VGPCSCGLRE AVDGVRFIAD HMRSEDDDQS VREDWKYVAM VIDRLFLWIF VFVCVFGTVG MFLQPLFQNY TATTFLHPDH SAPSSK. It is sometimes possible for the material contained within the vial of "Neuronal acetylcholine receptor subunit beta-2 (Chrnb2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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