Paxillin Phospho-Tyrosine Regulation Antibody Sampler Kit
Paxillin Phospho-Tyrosine Regulation
Reactivity
Human, Rat, Mouse, Chicken, Fish
Applications
Western Blot, ELISA
Synonyms
Paxillin Phospho-Tyrosine Regulation; PaxillinK3; Paxillin Phospho-Tyrosine Regulation antibody sampler kit
Reactivity
Human, Rat, Mouse, Chicken, Fish
Form/Format
Mouse monoclonal and rabbit polyclonal antibodies are supplied in phosphate-buffered saline, 50% glycerol, 1mg/ml BSA, and 0.05% sodium azide. The secondary reagents are supplied in the same buffer without azide.
Applicable Applications for Paxillin Phospho-Tyrosine Regulation antibody sampler kit
Western Blot (WB), ELISA (EIA)
Preparation and Storage
Store all at -20 degree C.Stable for 1 year.
Related Product Information for Paxillin Phospho-Tyrosine Regulation antibody sampler kit
Kit Summary: The paxillin phospho-tyrosine regulation antibody kit can be used to detect phosphorylation of paxillin at Tyr-31 and Tyr-118 relative to total paxillin expression. The kit includes mouse monoclonal and rabbit polyclonal antibodies to detectpaxillin expression, as well as secondary reagents for detection in western blot.
Background: Paxillin is involved in focal adhesion formation during cell adhesion and migration. Paxillin contains LD motifs, LIMdomains, and an SH3- and SH2-binding domain that participate in a variety of protein-protein interactions with kinases, GTPase-activating proteins, and cytoskeletal proteins. Phosphorylation of paxillin occurs at both tyrosine and serine sites.Tyrosine phosphorylation of paxillin occurs in response to growth factors, neuropeptides, and integrins. The major sitesof tyrosine phosphorylation include Tyr-31 and Tyr-118. Both of these sites may be involved in Crk binding to paxillinduring integrin-mediated cell adhesion. These sites may provide docking motifs for recruitment of other signalingmolecules to focal adhesions.
Background: Paxillin is involved in focal adhesion formation during cell adhesion and migration. Paxillin contains LD motifs, LIMdomains, and an SH3- and SH2-binding domain that participate in a variety of protein-protein interactions with kinases, GTPase-activating proteins, and cytoskeletal proteins. Phosphorylation of paxillin occurs at both tyrosine and serine sites.Tyrosine phosphorylation of paxillin occurs in response to growth factors, neuropeptides, and integrins. The major sitesof tyrosine phosphorylation include Tyr-31 and Tyr-118. Both of these sites may be involved in Crk binding to paxillinduring integrin-mediated cell adhesion. These sites may provide docking motifs for recruitment of other signalingmolecules to focal adhesions.
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Product Notes
The Human, Rat, Mouse, Chicken, Fish Paxillin Phospho-Tyrosine Regulation (Catalog #AAA474496) is an Antibody Sampler Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA474496 Antibody Sampler Kit recognizes Human, Rat, Mouse, Chicken, Fish Paxillin Phospho-Tyrosine Regulation. AAA Biotech's Paxillin Phospho-Tyrosine Regulation can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the Paxillin Phospho-Tyrosine Regulation for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Paxillin Phospho-Tyrosine Regulation, Antibody Sampler Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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