Chicken Killer cell immunoglobulin-like receptor (KIR) ELISA Kit | KIR elisa kit

Chicken Killer cell immunoglobulin-like receptor (KIR) ELISA Kit

Cat. Num. AAA266443

• Gene Names: KIR2DS1; p50.1; CD158H; CD158a
• Reactivity: Chicken
• Synonyms: Killer cell immunoglobulin-like receptor (KIR); Chicken Killer cell immunoglobulin-like receptor (KIR) ELISA Kit; KIR elisa kit

• Reactivity: Chicken
• Specificity: No cross-reaction with other factors.
• Sequence Length: 304

• Samples: Chicken Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant Itf Concentration
• Assay Type: Sandwich
• Detection Range: 10 ng/ml-0.156 ng/ml
• Sensitivity: 0.05 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for KIR elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Chicken ITF monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 7657277
• NCBI GeneID: 3806
• NCBI Accession #: NP_055327.1
• NCBI GenBank Nucleotide #: NM_014512.1
• Molecular Weight: 33,646 Da
• NCBI Official Full Name: killer cell immunoglobulin-like receptor 2DS1
• NCBI Official Synonym Full Names: killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
• NCBI Official Symbol: KIR2DS1
• NCBI Official Synonym Symbols: p50.1; CD158H; CD158a
• NCBI Protein Information: killer cell immunoglobulin-like receptor 2DS1; CD158 antigen-like family member H; MHC class I NK cell receptor Eb6 ActI; killer-cell immunoglobulin-like receptor; killer cell immunoglobulin-like receptor KIRDS1
• UniProt Protein Name: Killer cell immunoglobulin-like receptor 2DS1
• UniProt Gene Name: KIR2DS1
• UniProt Synonym Gene Names: CD158H
• UniProt Entry Name: KI2S1_HUMAN

NCBI Description

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Uniprot Description

KIR2DS1: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. Belongs to the immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: plasma membrane; integral to membrane

Molecular Function: transmembrane receptor activity

Biological Process: regulation of immune response; innate immune response; immune response; signal transduction