Chicken Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) ELISA Kit | ACOT7 elisa kit
Chicken Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
ACOT7: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl- CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; EC 3.1.2.2; Lipid Metabolism - unsaturated fatty acid biosynthesis
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: nucleoplasm; neuron projection; mitochondrion; cytoplasm; cytosol
Molecular Function: protein binding; protein homodimerization activity; acyl-CoA binding; palmitoyl-CoA hydrolase activity
Biological Process: medium-chain fatty acid biosynthetic process; coenzyme A biosynthetic process; fatty acid catabolic process
Research Articles on ACOT7
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Product Notes
The Chicken ACOT7 acot7 (Catalog #AAA7246777) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7246777 ELISA Kit recognizes Chicken ACOT7. It is sometimes possible for the material contained within the vial of "Cytosolic acyl coenzyme A thioester hydrolase (ACOT7), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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