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product-image-AAA269399_IHC13.png IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NELFe antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.)

Rabbit NELFE Monoclonal Antibody | anti-NELFE antibody

NELFE Rabbit mAb

Gene Names
NELFE; RD; RDP; RDBP; D6S45; NELF-E
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
NELFE, Antibody; NELFE Rabbit mAb; RD; RDP; RDBP; D6S45; NELF-E; anti-NELFE antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
R02-7E5
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Applicable Applications for anti-NELFE antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human NELFe
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NELFe antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.)

product-image-AAA269399_IHC13.png IHC (Immunohiostchemistry) (Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NELFe antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.)

WB (Western Blot)

(Western blot analysis of NELFe in C6 lysates using NELFE antibody.)

product-image-AAA269399_WB15.png WB (Western Blot) (Western blot analysis of NELFe in C6 lysates using NELFE antibody.)
Related Product Information for anti-NELFE antibody
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1
Product Categories/Family for anti-NELFE antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
380
NCBI Official Full Name
Negative elongation factor E
NCBI Official Synonym Full Names
negative elongation factor complex member E
NCBI Official Symbol
NELFE
NCBI Official Synonym Symbols
RD; RDP; RDBP; D6S45; NELF-E
NCBI Protein Information
negative elongation factor E; nuclear protein; RD RNA binding protein; RD RNA-binding protein; RNA-binding protein RD; major histocompatibility complex gene RD; negative elongation factor polypeptide E
UniProt Protein Name
Negative elongation factor E
UniProt Gene Name
NELFE
UniProt Synonym Gene Names
RD; RDBP; NELF-E
UniProt Entry Name
NELFE_HUMAN

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Product Notes

The NELFE nelfe (Catalog #AAA269399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NELFE Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NELFE can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NELFE nelfe for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NELFE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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