Chicken Cdc42 effector protein 5 (CDC42EP5) ELISA Kit | CDC42EP5 elisa kit
Chicken Cdc42 effector protein 5 (CDC42EP5) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
Uniprot Description
CDC42EP5: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42. Belongs to the BORG/CEP family.
Chromosomal Location of Human Ortholog: 19q13.42
Cellular Component: cytoskeleton; membrane; cytoplasm; plasma membrane; endomembrane system
Molecular Function: GTP-Rho binding
Biological Process: regulation of cell shape; positive regulation of pseudopodium formation; positive regulation of actin filament polymerization; JNK cascade; Rho protein signal transduction
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Product Notes
The Chicken CDC42EP5 cdc42ep5 (Catalog #AAA7229089) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7229089 ELISA Kit recognizes Chicken CDC42EP5. It is sometimes possible for the material contained within the vial of "Cdc42 effector protein 5 (CDC42EP5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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