Chicken cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA) ELISA Kit | PRKACA elisa kit

Chicken cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA) ELISA Kit

• Gene Names: Prkaca; PKCA1; Cs-PKA
• Reactivity: Chicken
• Synonyms: cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA); Chicken cAMP-Dependent Protein Kinase Catalytic Subunit Alpha (PRKACA) ELISA Kit; PRKACA elisa kit

• Reactivity: Chicken

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 155369271
• NCBI GeneID: 25636
• NCBI Accession #: NP_001094392.1
• NCBI GenBank Nucleotide #: NM_001100922.1
• Molecular Weight: 39,879 Da
• NCBI Official Full Name: cAMP-dependent protein kinase catalytic subunit alpha
• NCBI Official Synonym Full Names: protein kinase cAMP-activated catalytic subunit alpha
• NCBI Official Symbol: Prkaca
• NCBI Official Synonym Symbols: PKCA1; Cs-PKA
• NCBI Protein Information: cAMP-dependent protein kinase catalytic subunit alpha
• UniProt Protein Name: cAMP-dependent protein kinase catalytic subunit alpha
• Protein Family: cAMP-dependent protein kinase
• UniProt Gene Name: Prkaca
• UniProt Synonym Gene Names: PKA C-alpha
• UniProt Entry Name: KAPCA_RAT

NCBI Description

active catalytic subunit of protein kinase A; phosphorylates and activates transcription factors in response to elevated levels of cAMP; mediates phosphorylation and regulation of enzyme substrates involved in intermediary metabolism [RGD, Feb 2006]

Uniprot Description

PKACA: catalytic subunit of cAMP-dependent protein kinase alpha, an AGC kinase. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Two splice-variant isoforms have been described.

Protein type: Kinase, protein; Protein kinase, AGC; EC 2.7.11.11; Protein kinase, Ser/Thr (non-receptor); AGC group; PKA family

Cellular Component: AMP-activated protein kinase complex; cAMP-dependent protein kinase complex; centrosome; cytoplasm; cytosol; Golgi apparatus; membrane; mitochondrion; neuromuscular junction; neuron projection; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; protein complex

Molecular Function: ATP binding; cAMP-dependent protein kinase activity; protein binding; protein complex binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; Rab GTPase binding; ubiquitin protein ligase binding

Biological Process: mesoderm formation; negative regulation of meiotic cell cycle; neural tube closure; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of cell proliferation; positive regulation of protein export from nucleus; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of cellular respiration; regulation of osteoblast differentiation; regulation of synaptic transmission; regulation of synaptic transmission, glutamatergic; sperm capacitation