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Chitinase 3-Like 2 Recombinant Protein | CHI3L2 recombinant protein

Recombinant Human Chitinase 3-Like 2

Gene Names
CHI3L2; CHIL2; YKL39; YKL-39
Purity
Purity as determined by densitometric image analysis is greater than 95%.
Synonyms
Chitinase 3-Like 2; Recombinant Human Chitinase 3-Like 2; CHI3L2 Human; Chitinase 3-Like 2 Recombinant; Chondrocyte Protein 39; YKL-39; YKL39; Chitinase-3-Like Protein 2; CHIL2; CHI3L2; CHI3L2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Purity as determined by densitometric image analysis is greater than 95%.
Form/Format
CHI3L2 was filtered (0.4 um) and lyophilized from 0.5mg/ml solution in 30mM acetate buffer, pH 4.
Filtered White lyophilized (freeze-dried) powder.
Sequence
MKHHHHHHASYKLVCYFTNW SQDRQEPGKF TPENIDPFLC SHLIYSFASI ENNKVIIKDK SEVMLYQTIN SLKTKNPKLK ILLSIGGYLF GSKGFHPMVD SSTSRLEFIN SIILFLRNHN FDGLDVSWIY PDQKENTHFT VLIHELAEAF QKDFTKSTKE RLLLTAGVSA GRQMIDNSYQ VEKLAKDLDF INLLSFDFHG SWEKPLITGH NSPLSKGWQD RGPSSYYNVE YAVGYWIHKG MPSEKVVMGI PTYGHSFTLA SAETTVGAPA SGPGAAGPIT ESSGFLAYYE ICQFLKGAKI TRLQDQQVPY AVKGNQWVGY DDVKSMETKV QFLKNLNLGG AMIWSIDMDD FTGKSCNQGP YPLVQAVKRS LGSL.
Sequence Length
380
Preparation and Storage
Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
Related Product Information for CHI3L2 recombinant protein
Introduction: Chitinase 3-Like 2 (CHI3L2) is similar to bacterial chitinases but lacks chitinase activity. CHI3L2 protein is secreted and is involved in cartilage biogenesis. CHI3L2 is a lectin, which binds chitooligosaccharides and other glycans with high affinity, but not heparin.

Description: CHI3L2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain (Tyr27-Leu390) containing 374 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 42.1kDa.
Product Categories/Family for CHI3L2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,508 Da
NCBI Official Full Name
chitinase-3-like protein 2 isoform b
NCBI Official Synonym Full Names
chitinase 3 like 2
NCBI Official Symbol
CHI3L2
NCBI Official Synonym Symbols
CHIL2; YKL39; YKL-39
NCBI Protein Information
chitinase-3-like protein 2
UniProt Protein Name
Chitinase-3-like protein 2
Protein Family
UniProt Gene Name
CHI3L2
UniProt Entry Name
CH3L2_HUMAN

Uniprot Description

CHI3L2: Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity. Belongs to the glycosyl hydrolase 18 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: extracellular space

Molecular Function: chitin binding; chitinase activity

Biological Process: chitin catabolic process

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Product Notes

The CHI3L2 chi3l2 (Catalog #AAA140725) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MKHHHHH HASYKL VCYFTNW SQDRQEPGKF TPENIDPFLC SHLIYSFASI ENNKVIIKDK SEVMLYQTIN SLKTKNPKLK ILLSIGGYLF GSKGFHPMVD SSTSRLEFIN SIILFLRNHN FDGLDVSWIY PDQKENTHFT VLIHELAEAF QKDFTKSTKE RLLLTAGVSA GRQMIDNSYQ VEKLAKDLDF INLLSFDFHG SWEKPLITGH NSPLSKGWQD RGPSSYYNVE YAVGYWIHKG MPSEKVVMGI PTYGHSFTLA SAETTVGAPA SGPGAAGPIT ESSGFLAYYE ICQFLKGAKI TRLQDQQVPY AVKGNQWVGY DDVKSMETKV QFLKNLNLGG AMIWSIDMDD FTGKSCNQGP YPLVQAVKRS LGSL.. It is sometimes possible for the material contained within the vial of "Chitinase 3-Like 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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