Centrin 2 Recombinant Protein | CETN2 recombinant protein

Centrin 2 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121792

• Gene Names: CETN2; CALT; CEN2
• Purity: >90% as determined by SDS-PAGE
• Synonyms: Centrin 2; Centrin 2 Protein; Human; Recombinant (His Tag); Human CETN2/Centrin 2 Protein (His Tag); CALT Protein; CEN2 Protein; centrin; EF-hand protein; 2; CETN2 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Tyr171

• Species: Human
• Predicted N Terminal: His
• Tag: N-His
• Protein Construction: A DNA sequence encoding the human CETN2 (P41208)(Met1-Tyr171) was expressed with a polyhistidine tag at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 4757902
• NCBI GeneID: 1069
• NCBI Accession #: NP_004335.1
• NCBI GenBank Nucleotide #: NM_004344.1
• UniProt Accession #: P41208; Q53XW1; B2R4T4
• Molecular Weight: 19,738 Da
• NCBI Official Full Name: centrin-2
• NCBI Official Synonym Full Names: centrin, EF-hand protein, 2
• NCBI Official Symbol: CETN2
• NCBI Official Synonym Symbols: CALT; CEN2
• NCBI Protein Information: centrin-2; caltractin (20kD calcium-binding protein)
• UniProt Protein Name: Centrin-2
• Protein Family: Centrin
• UniProt Gene Name: CETN2
• UniProt Synonym Gene Names: CALT; CEN2
• UniProt Entry Name: CETN2_HUMAN

NCBI Description

Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]

Uniprot Description

CETN2: a calcium-binding proteins and is a structural component of the centrosome. Contains 4 EF-hand calcium-binding domains. Highly conserved from algae to humans. Its association with the centrosome suggests that it plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.

Protein type: Calcium-binding; Cell cycle regulation; DNA repair, damage

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: centriole; centrosome; intracellular; cytosol; photoreceptor connecting cilium

Molecular Function: protein binding; microtubule binding; G-protein beta/gamma-subunit binding; calcium ion binding; heterotrimeric G-protein binding

Biological Process: mitosis; cell division; nucleotide-excision repair; organelle organization and biogenesis; centriole replication; spermatogenesis; mitotic cell cycle; G2/M transition of mitotic cell cycle; regulation of cytokinesis