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Chemokine Assay System

Chemokine (C-X-C Motif) Receptor 4 (CXCR4) ACTOne Stable Cell Line

Synonyms
Chemokine; Chemokine (C-X-C Motif) Receptor 4 (CXCR4) ACTOne Stable Cell Line; Chemokine assay system
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Application Notes
cAMP dependent human CXCR4 cell-based assay; cell-based high-throughput screening of human CXCR4 inhibitors
Preparation and Storage
Product is shipped on dry ice. Storage: Remove the frozen cells from the dry ice packaging and immediately place the cells at a temperature below -130 degrees C preferably in liquid nitrogen vapor, until ready for use.
Related Product Information for Chemokine assay system
Background/Introduction: The C-X-C chemokine receptor type 4 (CXCR4) also known as fusin or CD184, is a receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells.

Similar Products

Product Notes

The Chemokine (Catalog #AAA433662) is an Assay System and is intended for research purposes only. The product is available for immediate purchase. cAMP dependent human CXCR4 cell-based assay; cell-based high-throughput screening of human CXCR4 inhibitors. Researchers should empirically determine the suitability of the Chemokine for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chemokine, Assay System" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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