CEL / Bile Salt-Activated Lipase Recombinant Protein | CEL recombinant protein
Human CEL / Bile Salt-Activated Lipase Recombinant Protein
NCBI and Uniprot Product Information
Uniprot Description
CEL: Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides. Defects in CEL are a cause of maturity-onset diabetes of the young type 8 with exocrine dysfunction (MODY8); also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.1.3; Secreted; EC 3.1.1.13; Lipase; Secreted, signal peptide; Lipid Metabolism - steroid biosynthesis; Lipid Metabolism - glycerolipid
Chromosomal Location of Human Ortholog: 9q34.3
Cellular Component: extracellular space; cytoplasm; extracellular region
Molecular Function: heparin binding; sterol esterase activity; triacylglycerol lipase activity; protein binding; hydrolase activity; acylglycerol lipase activity; catalytic activity
Biological Process: intestinal lipid catabolic process; triacylglycerol metabolic process; cholesterol absorption; lipid metabolic process; fatty acid catabolic process; protein amino acid esterification; pancreatic juice secretion; cholesterol catabolic process; lipid digestion
Disease: Maturity-onset Diabetes Of The Young, Type 8, With Exocrine Dysfunction
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Product Notes
The CEL cel (Catalog #AAA2903647) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CEL / Bile Salt-Activated Lipase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the CEL cel for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEL / Bile Salt-Activated Lipase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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