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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 Recombinant Protein | CEACAM3 recombinant protein

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3

Gene Names
CEACAM3; CEA; CGM1; W264; W282; CD66D
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3; Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3; CEACAM3 Human; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 Human Recombinant; Carcinoembryonic Antigen CGM1; CD66d Antigen; CD66D; CGM1; Carcinoembryonic Antigen Gene Family Member 1; Nonspecific Cross-Reacting Antigen; W264; W282; CEA; CEACAM3; CEACAM3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
CEACAM3 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4) and 20% glycerol.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSKLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAG
Sequence Length
212
Related Product Information for CEACAM3 recombinant protein
Introduction: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, also known as CEACAM3, is a member of the immunoglobulin super family. The genes in this family encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues rather than in normal tissues. CEACAM3 plays a significant part in the clearance of pathogens through the innate immune system. In addition, CEACAM3 is accountable for RAC1 stimulation in the course of pathogen phagocytosis.

Description: CEACAM3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 144 amino acids (35-155 a.a) and having a molecular mass of 15.5kDa.CEACAM3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for CEACAM3 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,754 Da
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 3 isoform 2
NCBI Official Synonym Full Names
carcinoembryonic antigen related cell adhesion molecule 3
NCBI Official Symbol
CEACAM3
NCBI Official Synonym Symbols
CEA; CGM1; W264; W282; CD66D
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 3
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 3
UniProt Gene Name
CEACAM3
UniProt Synonym Gene Names
CD66D; CGM1
UniProt Entry Name
CEAM3_HUMAN

Uniprot Description

CEACAM3: Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. Interacts with S100A9/calprotectin. This interaction is calcium-dependent, but independent of CEACAM3 phosphorylation. CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney. Belongs to the immunoglobulin superfamily. CEA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.2

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Product Notes

The CEACAM3 ceacam3 (Catalog #AAA141089) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSKLT IESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAG. It is sometimes possible for the material contained within the vial of "Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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