ZNF750 cdna clone
ZNF750 cDNA Clone
Gene Names
ZNF750; ZFP750
Synonyms
ZNF750; ZNF750 cDNA Clone; ZNF750 cdna clone
Sequence
ATGAGTCTCCTCAAAGAGCGGAAGCCAAAAAAGCCACATTACATCCCCAGGCCTCCAGGAAAGCCCTTCAAGTATAAATGTTTCCAATGTCCCTTTACTTGCAATGAGAAGTCACATCTTTTTAATCACATGAAGTATGGTCTTTGTAAAAACTCGATTACTTTAGTATCAGAGCAGGATCGAGTTCCCAAGTGCCCTAAATCTAACTCACTAGACCCCAAGCAAACCAACCAGCCCGATGCCACGGCGAAGCCAGCCTCTTCCAAGTCTGTCGCAAATGGACTCTCTGCCTTCGACTCGAAGCTTCAGCACAGCTCTGCCAGGGAAGACATCAAGGAAAACCTGGAGCTGCAAGCCCGGGGAACCCACAGGTGCCTGGGACAGAAGCCAGCCCTCCACAGGGCATCACCCTGCAAGAGCCCAGCTCCGGAAGCCGCCCTCGGTGCCCAGCCTGCTCTGGAAGGCGCAGCTCGGCCTTCTGCATTTGTTCCAGTCGGCGAGCACAGACTCAAGGGGCCAGACAACGCCGAGGCGCCCGAGACACTGGCTTTACACAACCCCACTGCCAAGGCCGTGTCTTTCCACACCAAGTCGGCCTTCCACACTCCTGGCTACCCCTGGAAAGCCGGCTCACCTTTCCTTCCACCAGAGTTTCCACATAAAATCTCATCTACAAAGGGGCTTGGGGCCATTTCCCCTTACATGCACCCCACAATCCCAGAGTACCCGCCTCACTTTTACACAGAGCACGGGCTGGCCACCATCTACTCGCCTTACCTGCTGGCTGGGAGCTCGCCTGAGTGTGACGCACCCCTGCTGTCAGTCTACGGAACCCAAGACCCGAGACACTTCCTGCCTCACCCGGGGCCGATCCCTAAGCACCTGGCTCCATCTCCAGCCACATACGATCACTACAGGTTTTTCCAGCAATATCCCTCTAACCTGCCGATTCCTTACGGATTTTACAGGCCAGAGTCTGCATTTTCCTCCTATGGTCTCAGACTCCCACCTGTCACTGGCCTCACCCGAGATCAGAGCTCTCACCTGCTTGAAGAAGCCACCCTGGTCTATCCAGCCTCGAGTCCTTCCAGGTTAAACCCTTCGGACCCCAACAGAAAACACGTCGAGTTCGAAAGTCCAATTCCTGAGGCTAAAGACTCCTCCAAGGCTGGGCAGAGAGACACGGAAGGGTCCAAAATGAGCCCCCGCGCAGGGAGTGCAGCCACGGGCTCCCCAGGGAGGCCGAGCCCCACCGACTTCATGCAGACGAGCCAGACCTGCGAAGGCCTGTACGACCTCTCCAACAAGGCAGCCTCCAGCGCACTGGGAAGACTCTACCCGCCAGAGCAAAGCCTCACAGCCTTCAGGCCTGTTAAGAAAAGCACAGAATGCCTACCTGCCCAGGCTGCTGAGACCACAGCAGAGTCTCCAGTAAGCCTCAATGTTGTGAACGGAGACCCTCCTGCTCCGACCGGAAGCGCCTCTCTCGTCTCGGAGGCCGCGCCTTCCAGTCCGGACGACAGCTCCGGGATGGGCCCCCTCAACCTCTCCAAGAAATCAGAGATAAACCTGGCAGCCACCCACGAACCCACGTACCAAGGCAGCCCCCAGGCGGAAACCGCCAGCTTCTCAGAGCTGCAGGACCTTCCACTCAATCTCTCGGTGAAGGACCCCTGTAACACCCAGGCTCCGAGGCCCGCCTTCCCCGGTCGACCACGAGCTGCGGAACCTGCTGCTGCTGTTCCACAGAAGACTGGGACAGAAGGTTCTGAGGATGGGCCCAGCCACCCTGAGACCAAGCCAGGCAGCCTCGACGGTGACGGGGCCCCACCCACAGGCCCCGGCGAGGAGGCTCCAGACGCATGCGCGGTGGACAGCAGCGAGGAGCAGAAGCAGACGGCAGCCGTGGCCCTGTGCCAGCTGGCGGCCTACAGCCCCAGGAACATCCGGGTGGGCGATGGGGATGCTGCGGCCCCGGAACCTGCCTGCCGGCAAGACACACCCACACTGAGCTCCATGGAGAGCCAAGAGGCCCAGTGTGACCTCAGACCCAAAGGACAAAAGAGGACAAGTCTAAGGGATGCTGGAAAATCCCAGCAAGGAGCTAAGAAGGCGAAGCTGCAGGACACGGCCAGAGTGTTCACACTACGAAGGAGGGCCCGGGTGTCCTAA
Sequence Length
2172
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
77,361 Da
NCBI Official Full Name
Homo sapiens zinc finger protein 750, mRNA
NCBI Official Synonym Full Names
zinc finger protein 750
NCBI Official Symbol
ZNF750
NCBI Official Synonym Symbols
ZFP750
NCBI Protein Information
zinc finger protein 750
UniProt Protein Name
Zinc finger protein 750
Protein Family
UniProt Gene Name
ZNF750
UniProt Entry Name
ZN750_HUMAN
NCBI Description
This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]
Uniprot Description
ZNF750: Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression. Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP). SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus
Molecular Function: protein binding
Biological Process: epidermis development; positive regulation of transcription from RNA polymerase II promoter
Disease: Seborrhea-like Dermatitis With Psoriasiform Elements
Research Articles on ZNF750
Similar Products
Product Notes
The ZNF750 znf750 (Catalog #AAA1267117) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC ACCCAGGCTC CGAGGCCCGC CTTCCCCGGT CGACCACGAG CTGCGGAACC TGCTGCTGCT GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC CGGGTGTCCT AA. It is sometimes possible for the material contained within the vial of "ZNF750, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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