ZNF384 cdna clone
ZNF384 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
Uniprot Description
ZNF384: Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 12p12
Research Articles on ZNF384
Similar Products
Product Notes
The ZNF384 znf384 (Catalog #AAA1272464) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggaagaat ctcacttcaa ttctaacccg tacttctggc cttctatccc cacagtctca ggtcagatcg agaacacaat gttcatcaac aagatgaagg atcagctgtt gccagagaag ggctgtggtc tggccccacc tcactacccc accttgctga cagtgcctgc ctcagtgtcc ctgccctcag gcatcagtat ggacacagag tccaagtcag accagctgac cccacacagc caagcgtccg ttacccagaa tatcacggtg gtccctgtgc cgtctacagg actgatgact gctgccctgc aggttgtccc tgacctctcc aagaaggtag catcgaccct aaccgaggaa ggaggcggag gtggtggtgg aggtggcagt gtggctccta agccaccccg gggccggaag aagaagcgga tgctggaatc agggctgccc gagatgaatg acccttatgt cctctcccct gaggatgatg atgaccatca gaaagacggc aagacctaca ggtgccggat gtgctcactg acattctact ccaagtcgga gatgcagatc cactccaagt cacacaccga gaccaagccc cacaagtgcc cacattgctc caagaccttc gccaacagct cctacctggc ccagcacatc cgtatacact caggggctaa gccctacagt tgtaacttct gtgagaaatc cttccgccag ctctcccacc ttcagcagca cacccgaatc cacactggtg atagaccata caaatgtgca cacccaggct gtgagaaagc cttcacacaa ctctccaatc tgcagtccca cagacggcaa cacaacaaag ataaaccctt caagtgccac aactgtcatc gggcgtacac ggatgcagcc tcactagagg tgcacctgtc tacgcacaca gtgaagcatg ccaaggtgta cacctgcact atctgcagtc gggcatacac atcagaaaca taccttatga aacatatgcg caaacacaac ccgcctgatc ttcagcaaca ggtgcaggca gcagcagcag cggcagcagt ggcccaggcc caggctcaag ctcaagccca ggctcaggct caggctcaag cccaggccca ggcccaggcc tcccaggcat cacagcagca gcagcagcag cagcagcagc agcagcagca gcaacagcca ccaccacact tccagtctcc tggggcagcc ccccagggtg ggggtggtgg ggacagcaat cccaaccctc caccccagtg ttcctttgac ctgaccccgt ataagacggc ggagcatcat aaggacatct gcctcactgt caccaccagc accatccagg tggagcacct ggccagctct tag. It is sometimes possible for the material contained within the vial of "ZNF384, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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