XPNPEP1 cdna clone
XPNPEP1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
Uniprot Description
XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.11.9; Protease
Chromosomal Location of Human Ortholog: 10q25.3
Cellular Component: cytoplasm
Molecular Function: aminopeptidase activity; manganese ion binding; protein homodimerization activity
Biological Process: proteolysis
Research Articles on XPNPEP1
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Product Notes
The XPNPEP1 xpnpep1 (Catalog #AAA1271768) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcctccaa aggtgacttc agagctgctt cggcagctga gacaagccat gaggaactct gagtatgtga ccgaaccgat ccaggcctac atcatcccat cgggagatgc tcatcagagt gagtatattg ctccatgtga ctgtcggcgg gcttttgtct ctggattcga tggctctgcg ggcacagcca tcatcacaga agagcatgca gccatgtgga ctgacgggcg ctactttctc caggctgcca agcaaatgga cagcaactgg acacttatga agatgggtct gaaggacaca ccaactcagg aagactggct ggtgagtgtg cttcctgaag gatccagggt tggtgtggac cccttgatca ttcctacaga ttattggaag aaaatggcca aagttctgag aagtgccggc catcacctca ttcctgtcaa ggagaacctc gttgacaaaa tctggacaga ccgtcctgag cgcccttgca agcctctcct cacactgggc ctggattaca caggcatctc ctggaaggac aaggttgcag accttcggtt gaaaatggct gagaggaacg tcatgtggtt tgtggtcact gccttggatg agattgcgtg gctatttaat ctccgaggat cagatgtgga gcacaatcca gtatttttct cctacgcaat cataggacta gagacgatca tgctcttcat tgatggtgac cgcatagacg cccccagtgt gaaggagcac ctgcttcttg acttgggtct ggaagccgaa tacaggatcc aggtgcatcc ctacaagtcc atcctgagcg agctcaaggc cctgtgtgct gacctctccc caagggagaa ggtgtgggtc agtgacaagg ccagctatgc tgtgagcgag accatcccca aggaccaccg ctgctgtatg ccttacaccc ccatctgcat cgccaaagct gtgaagaatt cagctgagtc agaaggcatg aggcgggctc acattaaaga tgctgttgct ctctgtgaac tctttaactg gctggagaaa gaggttccca aaggtggtgt gacagagatc tcagctgctg acaaagctga ggagtttcgc aggcaacagg cagactttgt ggacctgagc ttcccaacaa tttccagtac gggacccaac ggcgccatca ttcactacgc gccagtccct gagacgaata ggaccttgtc cctggatgag gtgtacctta ttgactcggg tgctcaatac aaggatggca ccacagatgt gacgcggaca atgcattttg ggacccctac agcctacgag aaggaatgct tcacatatgt cctcaagggc cacatagctg tgagtgcagc cgttttcccg actggaacca aaggtcacct tcttgactcc tttgcccgtt cagctttatg ggattcaggc ctagattact tgcacgggac tggacatggt gttgggtctt ttttgaatgt ccatgagggt ccttgcggca tcagttacaa aacattctct gatgagccct tggaggcagg catgattgtc actgatgagc ccgggtacta tgaagatggg gcttttggaa ttcgcattga gaatgttgtc cttgtggttc ctgtgaagac caagtataat tttaataacc ggggaagcct gacctttgaa cctctaacat tggttccaat tcagaccaaa atgatagatg tggattctct tacagacaaa gagtgcgact ggctcaacaa ttaccacctg acctgcaggg atgtgattgg gaaggaattg cagaaacagg gccgccagga agctctcgag tggctcatca gagagacgca acccatctcc aaacagcatt aa. It is sometimes possible for the material contained within the vial of "XPNPEP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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