USP25 cdna clone
USP25 cDNA Clone
Gene Names
USP25; USP21
Synonyms
USP25; USP25 cDNA Clone; USP25 cdna clone
Sequence
atgaccgtggagcagaacgtgctgcagcagagcgcggcgcagaagcaccagcagacgtttttgaatcaactgagagaaattacggggattaatgacacccagatactacagcaagccttgaaggatagtaatggaaacttggaattagcagtggctttccttactgcgaagaatgctaagacccctcagcaggaggagacaacttactaccaaacagcacttcctggcaatgatagatacatcagtgtgggaagccaagcagatacaaatgtgattgatctcactggagatgataaagatgatcttcagagagcaattgccttgagtttggccgaatcaaacagggcattcagggagactggaataactgatgaggaacaagccattagcagagttcttgaagccagcatagcagagaataaagcatgtttgaagaggacacctacagaagtttggagggattctcgaaacccttatgatagaaaaagacaggacaaagctcccgttgggctaaagaatgttggcaatacttgttggtttagtgctgttattcagtcattatttaatcttttggaatttagaagattagttctgaattacaagcctccatcaaatgctcaagatttaccccgaaaccaaaaggaacatcggaatttgccttttatgcgtgagctgaggtatctatttgcacttcttgttggtaccaaaaggaagtatgttgatccatcaagagcagttgaaattcttaaggatgctttcaaatcaaatgactcacagcagcaagatgtgagtgagtttacacacaaattattagattggttagaagatgccttccaaatgaaagctgaagaggagacggatgaagagaagccaaagaaccccatggtagagttgttctatggcagattcctggctgtgggagtacttgaaggtaaaaaatttgaaaacactgaaatgtttggtcagtacccacttcaggtcaatgggttcaaagatctgcatgagtgcctagaagctgcaatgattgaaggagaaattgagtctttacattcagagaattcaggaaaatcaggccaagagcattggtttactgaattaccacctgtgttaacatttgaattgtcaagatttgaatttaatcaggcattgggaagaccagaaaaaattcacaacaaattagaatttccccaagttttatatttggacagatacatgcacagaaacagagaaataacaagaattaagagggaagagatcaagagactgaaagattacctcacggtattacaacaaaggctagaaagatatttaagctatggttccggtcccaaacgattccccttggtagatgttcttcagtatgcattggaatttgcctcaagtaaacctgtttgcacttctcctgttgacgatattgacgctagttccccacctagtggttccataccatcacagacattaccaagcacaacagaacaacagggagccctatcttcagaactgccaagcacatcaccttcatcagttgctgccatttcatcgagatcagtaatacacaaaccatttactcagtcccggatacctccagatttgcccatgcatccggcaccaaggcacataacggaggaagaactttctgtgctggaaagttgtttacatcgctggaggacagaaatagaaaatgacaccagagatttgcaggaaagcatatccagaatccatcgaacaattgaattaatgtactctgacaaatctatgatacaagttccttatcgattacatgccgttttagttcacgaaggccaagctaatgctgggcactactgggcatatatttttgatcatcgtgaaagcagatggatgaagtacaatgatattgctgtgacaaaatcatcatgggaagagctagtgagggactcttttggtggttatagaaatgccagtgcatactgtttaatgtacataaatgataaggcacagttcctaatacaagaggagtttaataaagaaactgggcagccccttgttggtatagaaacattaccaccggatttgagagattttgttgaggaagacaaccaacgatttgaaaaagaactagaagaatgggatgcacaacttgcccagaaagctttgcaggaaaagcttttagcgtctcagaaattgagagagtcagagacttctgtgacaacagcacaagcagcaggagacccagaatatctagagcagccatcaagaagtgatttctcaaagcacttgaaagaagaaactattcaaataattaccaaggcatcacatgagcatgaagataaaagtcctgaaacagttttgcagtcggcaattaagttggaatatgcaaggttggttaagttggcccaagaagacaccccaccagaaaccgattatcgtttacatcatgtagtggtctactttatccagaaccaggcaccaaagaaaattattgagaaaacattactagaacaatttggagatagaaatttgagttttgatgaaaggtgtcacaacataatgaaagttgctcaagccaaactggaaatgataaaacctgaagaagtaaacttggaggaatatgaggagtggcatcaggattataggaaattcagggaaacaactatgtatctcataattgggctagaaaattttcaaagagaaagttatatagattccttgctgttcctcatctgtgcttatcagaataacaaagaactcttgtctaaaggcttatacagaggacatgatgaagaattgatatcacattatagaagagaatgtttgctaaaattaaatgagcaagccgcagaactcttcgaatctggagaggatcgagaagtaaacaatggtttgattatcatgaatgagtttattgtcccatttttgccattattactggtggatgaaatggaagaaaaggatatactagctgtagaagatatgagaaatcgatggtgttcctaccttggtcaagaaatggaaccacacctccaagaaaagctgacagattttttgccaaaactgcttgattgttctatggagattaaaagtttccatgagccaccgaagttaccttcatattccacgcatgaactctgtgagcgatttgcccgaatcatgttgtccctcagtcgaactcctgctgatggaagataa
Sequence Length
3168
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
129,963 Da
NCBI Official Full Name
Homo sapiens ubiquitin specific peptidase 25, mRNA
NCBI Official Synonym Full Names
ubiquitin specific peptidase 25
NCBI Official Symbol
USP25
NCBI Official Synonym Symbols
USP21
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 25
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 25
UniProt Gene Name
USP25
UniProt Synonym Gene Names
USP21
UniProt Entry Name
UBP25_HUMAN
NCBI Description
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008]
Uniprot Description
USP25: Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains. Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-specific protease; Protease; Ubiquitin conjugating system; EC 3.4.19.12
Chromosomal Location of Human Ortholog: 21q11.2
Cellular Component: cytoplasm; endoplasmic reticulum
Molecular Function: ATPase binding; peptidase activity; protein binding; SUMO binding; ubiquitin protein ligase binding; ubiquitin-specific protease activity
Biological Process: protein deubiquitination; protein modification process; proteolysis
Research Articles on USP25
Similar Products
Product Notes
The USP25 usp25 (Catalog #AAA1273362) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaccgtgg agcagaacgt gctgcagcag agcgcggcgc agaagcacca gcagacgttt ttgaatcaac tgagagaaat tacggggatt aatgacaccc agatactaca gcaagccttg aaggatagta atggaaactt ggaattagca gtggctttcc ttactgcgaa gaatgctaag acccctcagc aggaggagac aacttactac caaacagcac ttcctggcaa tgatagatac atcagtgtgg gaagccaagc agatacaaat gtgattgatc tcactggaga tgataaagat gatcttcaga gagcaattgc cttgagtttg gccgaatcaa acagggcatt cagggagact ggaataactg atgaggaaca agccattagc agagttcttg aagccagcat agcagagaat aaagcatgtt tgaagaggac acctacagaa gtttggaggg attctcgaaa cccttatgat agaaaaagac aggacaaagc tcccgttggg ctaaagaatg ttggcaatac ttgttggttt agtgctgtta ttcagtcatt atttaatctt ttggaattta gaagattagt tctgaattac aagcctccat caaatgctca agatttaccc cgaaaccaaa aggaacatcg gaatttgcct tttatgcgtg agctgaggta tctatttgca cttcttgttg gtaccaaaag gaagtatgtt gatccatcaa gagcagttga aattcttaag gatgctttca aatcaaatga ctcacagcag caagatgtga gtgagtttac acacaaatta ttagattggt tagaagatgc cttccaaatg aaagctgaag aggagacgga tgaagagaag ccaaagaacc ccatggtaga gttgttctat ggcagattcc tggctgtggg agtacttgaa ggtaaaaaat ttgaaaacac tgaaatgttt ggtcagtacc cacttcaggt caatgggttc aaagatctgc atgagtgcct agaagctgca atgattgaag gagaaattga gtctttacat tcagagaatt caggaaaatc aggccaagag cattggttta ctgaattacc acctgtgtta acatttgaat tgtcaagatt tgaatttaat caggcattgg gaagaccaga aaaaattcac aacaaattag aatttcccca agttttatat ttggacagat acatgcacag aaacagagaa ataacaagaa ttaagaggga agagatcaag agactgaaag attacctcac ggtattacaa caaaggctag aaagatattt aagctatggt tccggtccca aacgattccc cttggtagat gttcttcagt atgcattgga atttgcctca agtaaacctg tttgcacttc tcctgttgac gatattgacg ctagttcccc acctagtggt tccataccat cacagacatt accaagcaca acagaacaac agggagccct atcttcagaa ctgccaagca catcaccttc atcagttgct gccatttcat cgagatcagt aatacacaaa ccatttactc agtcccggat acctccagat ttgcccatgc atccggcacc aaggcacata acggaggaag aactttctgt gctggaaagt tgtttacatc gctggaggac agaaatagaa aatgacacca gagatttgca ggaaagcata tccagaatcc atcgaacaat tgaattaatg tactctgaca aatctatgat acaagttcct tatcgattac atgccgtttt agttcacgaa ggccaagcta atgctgggca ctactgggca tatatttttg atcatcgtga aagcagatgg atgaagtaca atgatattgc tgtgacaaaa tcatcatggg aagagctagt gagggactct tttggtggtt atagaaatgc cagtgcatac tgtttaatgt acataaatga taaggcacag ttcctaatac aagaggagtt taataaagaa actgggcagc cccttgttgg tatagaaaca ttaccaccgg atttgagaga ttttgttgag gaagacaacc aacgatttga aaaagaacta gaagaatggg atgcacaact tgcccagaaa gctttgcagg aaaagctttt agcgtctcag aaattgagag agtcagagac ttctgtgaca acagcacaag cagcaggaga cccagaatat ctagagcagc catcaagaag tgatttctca aagcacttga aagaagaaac tattcaaata attaccaagg catcacatga gcatgaagat aaaagtcctg aaacagtttt gcagtcggca attaagttgg aatatgcaag gttggttaag ttggcccaag aagacacccc accagaaacc gattatcgtt tacatcatgt agtggtctac tttatccaga accaggcacc aaagaaaatt attgagaaaa cattactaga acaatttgga gatagaaatt tgagttttga tgaaaggtgt cacaacataa tgaaagttgc tcaagccaaa ctggaaatga taaaacctga agaagtaaac ttggaggaat atgaggagtg gcatcaggat tataggaaat tcagggaaac aactatgtat ctcataattg ggctagaaaa ttttcaaaga gaaagttata tagattcctt gctgttcctc atctgtgctt atcagaataa caaagaactc ttgtctaaag gcttatacag aggacatgat gaagaattga tatcacatta tagaagagaa tgtttgctaa aattaaatga gcaagccgca gaactcttcg aatctggaga ggatcgagaa gtaaacaatg gtttgattat catgaatgag tttattgtcc catttttgcc attattactg gtggatgaaa tggaagaaaa ggatatacta gctgtagaag atatgagaaa tcgatggtgt tcctaccttg gtcaagaaat ggaaccacac ctccaagaaa agctgacaga ttttttgcca aaactgcttg attgttctat ggagattaaa agtttccatg agccaccgaa gttaccttca tattccacgc atgaactctg tgagcgattt gcccgaatca tgttgtccct cagtcgaact cctgctgatg gaagataa. It is sometimes possible for the material contained within the vial of "USP25, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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