SOAT2 cdna clone
SOAT2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
Uniprot Description
SOAT2: Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Protein type: Lipid Metabolism - steroid biosynthesis; Membrane protein, multi-pass; EC 2.3.1.26; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: brush border; endoplasmic reticulum; endoplasmic reticulum membrane
Molecular Function: acyl-CoA binding; cholesterol binding; transferase activity, transferring acyl groups
Biological Process: cholesterol absorption; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process
Research Articles on SOAT2
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Product Notes
The SOAT2 soat2 (Catalog #AAA1278877) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGCCAG GCGGGGCCCG TCTGCGTCTG CAGAGGACAG GAGGGCTGGG AGGGGAGCGG GAGCGCCAAC CCTGTGGAGA TGGAAACACT GAGACGCACA GAGCCCCGGA CTTGGTACAA TGGACCCGAC ACATGGAGGC TGTGAAGGCA CAATTGCTGG AGCAAGCGCA GGGACAACTG AGGGAGCTGC TGGATCGGGC CATGCGGGAG GCTATACAAT CCTACCCATC ACAAGACAAA CCTCTGCCCC CACCTCCCCC AGGTTCCTTG AGCAGGACCC AGGAGCCATC CCTGGGGAAA CAGAAAGTTT TCATCATCCG CAAGTCCCTG CTTGATGAGC TGATGGAGGT GCAGCATTTC CGCACCATCT ACCACATGTT CATCGCTGGC CTGTGTGTCT TCATCATCAG CACCCTGGCC ATCGACTTCA TTGATGAGGG CAGGCTGCTG CTGGAGTTTG ACCTACTGAT CTTCAGCTTC GGACAGCTGC CATTGGCGCT GGTGACCTGG GTGCCCATGT TTCTGTCCAC CCTGTTGGCG CCGTACCAGG CCCTACGGCT GTGGGCCAGG GGCACCTGGA CGCAGGCGAC GGGCCTGGGC TGTGCGCTTT TAGCCGCCCA CGCCGTGGTG CTCTGCGCGC TGCCGGTCCA CGTGGCCGTG GAGCATCAGC TCCCGCCGGC CTCCCGTTGT GTCCTGGTCT TCGAGCAGGT TAGGTTCCTG ATGAAAAGCT ACTCCTTCCT GAGAGAGGCT GTGCCTGGGA TCCTTCGTGC CAGACGAGGT GAGGGGATCC AGGCCCCCAG TTTCTCCAGC TACCTCTACT TCCTCTTCTG CCCAACACTC ATCTACAGGG AGACTTACCC TAGGACGCCC TATGTCAGGT GGAATTATGT GGCCAAGAAC TTTGCCCAGG CCCTGGGATG TGTGCTCTAT GCCTGCTTCA TCCTGGGCCG CCTCTGTGTT CCTGTCTTTG CCAACATGAG CCGAGAGCCC TTCAGCACCC GTGCCCTGGT GCTCTCTATC CTGCATGCCA CGTTGCCAGG CATCTTCATG CTGCTGCTCA TCTTCTTTGC CTTCCTCCAT TGCTGGCTCA ACGCCTTTGC CGAGATGCTA CGATTTGGAG ACAGGATGTT CTACCGGGAC TGGTGGAACT CAACGTCCTT CTCCAACTAC TACCGCACTT GGAACGTGGT GGTCCATGAC TGGCTGTACA GCTACGTGTA TCAGGATGGG CTGCGGCTCC TTGGTGCCCG GGCCCGAGGG GTAGCCATGC TGGGTGTGTT CCTGGTCTCC GCAGTGGCCC ATGAGTATAT CTTCTGCTTC GTCCTGGGGT TCTTCTATCC CGTCATGCTG ATACTCTTCC TTGTCATTGG AGGAATGTTG AACTTCATGA TGCATGACCA GCGCACCGGC CCGGCATGGA ACGTGCTGAT GTGGACCATG CTGTTTCTAG GCCAGGGAAT CCAGGTCAGC CTGTACTGCC AGGAGTGGTA CGCACGGCGG CACTGCCCCT TACCCCAGGC AACTTTCTGG GGGCTGGTGA CACCTCGATC TTGGTCCTGC CATACCTAG. It is sometimes possible for the material contained within the vial of "SOAT2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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