SLC5A2 cdna clone
SLC5A2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]
Uniprot Description
SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: glucose:sodium symporter activity; low-affinity glucose:sodium symporter activity
Biological Process: carbohydrate metabolic process; transport
Disease: Renal Glucosuria
Research Articles on SLC5A2
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Product Notes
The SLC5A2 slc5a2 (Catalog #AAA1275457) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGGAGC ACACAGAGGC AGGCTCGGCA CCAGAGATGG GGGCCCAGAA GGCCCTGATT GACAATCCTG CTGACATCCT AGTCATTGCT GCATATTTCC TGCTGGTCAT TGGCGTTGGC TTGTGGTCCA TGTGCAGAAC CAACAGAGGC ACTGTGGGCG GCTACTTCCT GGCAGGACGC AGCATGGTGT GGTGGCCGGT TGGGGCCTCT CTCTTCGCCA GCAACATCGG CAGTGGCCAC TTTGTGGGCC TGGCAGGGAC TGGCGCTGCA AGTGGCTTGG CTGTTGCTGG ATTCGAGTGG AATGCGCTCT TCGTGGTGCT GCTACTGGGC TGGCTGTTTG CACCCGTGTA CCTGACAGCG GGGGTCATCA CGATGCCACA GTACCTGCGC AAGCGCTTCG GCGGCCGCCG CATCCGCCTC TACCTGTCTG TGCTCTCCCT TTTCCTGTAC ATCTTCACCA AGATCTCAGT GGACATGTTC TCCGGAGCTG TATTCATCCA GCAGGCTCTG GGCTGGAACA TCTATGCCTC CGTCATCGCG CTTCTGGGCA TCACCATGAT TTACACGGTG ACAGGAGGGC TGGCCGCGCT GATGTACACG GACACGGTAC AGACCTTCGT CATTCTGGGG GGCGCCTGCA TCCTCATGGG TTACGCCTTC CACGAGGTGG GCGGGTATTC GGGTCTCTTC GACAAATACC TGGGAGCAGC GACTTCGCTG ACGGTGTCCG AGGATCCAGC CGTGGGAAAC ATCTCCAGCT TCTGCTATCG ACCCCGGCCC GACTCCTACC ACCTGCTCCG GCACCCCGTG ACCGGGGATC TGCCGTGGCC CGCGCTGCTC CTCGGACTCA CAATCGTCTC GGGCTGGTAC TGGTGCAGCG ACCAGGTCAT CGTGCAGCGC TGCCTGGCCG GGAAGAGCCT GACCCACATC AAGGCGGGCT GCATCCTGTG TGGGTACCTG AAGCTGACGC CCATGTTTCT CATGGTCATG CCAGGCATGA TCAGCCGCAT TCTGTACCCA GACGAGGTGG CGTGCGTGGT GCCTGAGGTG TGCAGGCGCG TGTGCGGCAC GGAGGTGGGC TGCTCCAACA TCGCCTACCC GCGGCTCGTC GTGAAGCTCA TGCCCAACGG GCGCCTTCTG GGGACTCATC GGGGGCCTGC TGATGGGCCT GGCACGCCTG ATTCCCGAGT TCTCCTTCGG CTCGGGCAGC TGTGTGCAGC CCTCGGCGTG CCCAGCTTTC CTCTGCGGCG TGCACTACCT CTACTTCGCC ATTGTGCTGT TCTTCTGCTC TGGCCTCCTC ACCCTCACGG TCTCCCTGTG CACCGCGCCC ATCCCCAGAA AGCACCTCCA CCGCCTGGTC TTCAGTCTCC GGCATAG. It is sometimes possible for the material contained within the vial of "SLC5A2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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