SH3BP4 cdna clone
SH3BP4 cDNA Clone
Gene Names
SH3BP4; TTP; BOG25
Synonyms
SH3BP4; SH3BP4 cDNA Clone; SH3BP4 cdna clone
Sequence
atggcggctcagcggatccgagcggccaactccaatggcctccctcgctgcaagtcagaggggaccctgattgacctgagcgaagggttttcagagacgagctttaatgacatcaaagtgccttctcccagtgccttgctcgtagacaaccccacacctttcggaaatgcaaaggaagtgattgcgatcaaggactattgccccaccaacttcaccacactgaagttctccaagggcgaccatctctacgtcttggacacatctggcggtgagtggtggtacgcacacaacaccaccgaaatgggctacatcccctcctcctatgtgcagcccttgaactaccggaactcaacactgagtgacagcggtatgattgataatcttccagacagcccagacgaggtagccaaggagctggagctgctcgggggatggacagatgacaaaaaagtaccaggcagaatgtacagtaataaccctttctggaatggggtccagaccaatccatttctgaatgggaacgtgcccgtcatgcccagcctggatgagctgaatcccaaaagtactgtggatttgctcctttttgacgcaggtacatcctccttcaccgaatccagctcagccaccacgaatagcactggcaacatcttcgatgagcttccagtcacaaacggactccacgcagagccgccggtcaggcgggacaaccccttcttcagaagcaagcgctcctacagtctctcggaactctccgtcctccaagccaagtccgatgctcccacatcgtcgagtttcttcaccggcttgaaatcacctgcccccgagcaatttcagagccgggaggattttcgaactgcctggctaaaccacaggaagctggcccggtcttgccacgacctggacttgcttggccaaagccctggttggggccagacccaagccgtggagacaaacatcgtgtgcaagctggatagctccgggggtgctgtccagcttcctgacaccagcatcagcatccacgtgcccgagggccacgtcgcccctggggagacccagcagatctccatgaaagccctgctggaccccccgctggagctcaacagtgacaggtcctgcagcatcagccctgtgctggaggtcaagctgagcaacctggaggtgaaaacctctatcatcttggagatgaaagtgtcagccgagataaaaaatgacctttttagcaaaagcacagtgggcctccagtgcctgaggagcgactcgaaggaagggccatatgtctccgtcccgctcaactgcagctgtggggacacggtccaggcacagctgcacaacctggagccctgtatgtacgtggctgtcgtggcccatggcccaagcatcctctacccttccaccgtgtgggacttcatcaataaaaaagtcacagtgggtctctacggccctaaacacatccacccatccttcaagacggtagtgaccatttttgggcatgactgtgccccaaagacgctcctggtcagcgaggtcacacgccaggcacccaaccctgccccggtggccctgcagctgtgggggaagcaccagttcgttttgtccaggccccaggatctcaaggtctgtatgttttccaatatgacgaattacgaggtcaaagccagcgagcaggccaaagtggtgcgaggattccagctgaagctgggcaaggtgagccgcctgatcttccccatcacctcccagaaccccaacgagctctctgacttcacgctgcgggttcaggtgaaggacgaccaggaggccatcctcacccagttttgtgtccagactcctcagccaccccctaaaagtgccatcaagccttccgggcaaaggaggtttctcaagaagaacgaagtcgggaaaatcatcctgtccccgtttgccaccactacaaagtacccgactttccaggaccgcccggtgtccagcctcaagtttggtaagttgctcaagactgtggtgcggcagaacaagaaccactacctgctggagtacaagaagggcgacgggatcgccctgctcagcgaggagcgggtcaggctccggggccagctgtggaccaaggagtggtacatcggctactaccagggcagggtgggcctcgtgcacaccaagaacgtgctggtggtcggcagggcccggcccagcctgtgctcgggccccgagctgagcacctcggtgctgctggagcagatcctgcggccctgcaaattcctcacgtacatctatgcctccgtgaggaccctgctcatggagaacatcagcagctggcgctccttcgctgacgccctgggctacgtgaacctgccgctcacctttttctgccgggcagagctggatagtgagcccgagcgggtggcgtccgtcctagaaaagctgaaggaggactgtaacaacactgagaacaaagaacggaagtccttccagaaggagcttgtgatggccctactgaagatggactgccagggcctggtggtcagactcatccaggactttgtgctcctgaccacggctgtagaggtggcccagcgctggcgggagctggctgagaagctggccaaggtctccaagcagcagatggacgcctacgagtctccccaccgggacaggaacggggttgtggacagcgaggccatgtggaagcctgcgtatgacttcttactcacctggagccatcagatcggggacagctaccgggatgtcatccaggagctgcacctgggcctggacaagatgaaaaaccccatcaccaagcgctggaagcacctcactgggactctgatcttggtgaactccctggacgttctgagagcagccgccttcagccctgcggaccaggacgacttcgtgatttga
Sequence Length
2892
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,337 Da
NCBI Official Full Name
Homo sapiens SH3-domain binding protein 4, mRNA
NCBI Official Synonym Full Names
SH3 domain binding protein 4
NCBI Official Symbol
SH3BP4
NCBI Official Synonym Symbols
TTP; BOG25
NCBI Protein Information
SH3 domain-binding protein 4
UniProt Protein Name
SH3 domain-binding protein 4
Protein Family
UniProt Gene Name
SH3BP4
UniProt Synonym Gene Names
BOG25; EHB10; TTP
UniProt Entry Name
SH3B4_HUMAN
NCBI Description
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
SH3BP4: Functions in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin- mediated endocytosis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Cell cycle regulation
Chromosomal Location of Human Ortholog: 2q37.1-q37.2
Cellular Component: cytoplasm
Molecular Function: GDP-dissociation inhibitor activity; identical protein binding; protein binding; Ras GTPase binding
Biological Process: amino acid import; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of TOR signaling pathway; positive regulation of autophagy; regulation of catalytic activity
Research Articles on SH3BP4
1. SH3BP4 is a negative regulator of the Rag GTPase complex and amino acid-dependent mTORC1 signaling.
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Product Notes
The SH3BP4 sh3bp4 (Catalog #AAA1269428) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcggctc agcggatccg agcggccaac tccaatggcc tccctcgctg caagtcagag gggaccctga ttgacctgag cgaagggttt tcagagacga gctttaatga catcaaagtg ccttctccca gtgccttgct cgtagacaac cccacacctt tcggaaatgc aaaggaagtg attgcgatca aggactattg ccccaccaac ttcaccacac tgaagttctc caagggcgac catctctacg tcttggacac atctggcggt gagtggtggt acgcacacaa caccaccgaa atgggctaca tcccctcctc ctatgtgcag cccttgaact accggaactc aacactgagt gacagcggta tgattgataa tcttccagac agcccagacg aggtagccaa ggagctggag ctgctcgggg gatggacaga tgacaaaaaa gtaccaggca gaatgtacag taataaccct ttctggaatg gggtccagac caatccattt ctgaatggga acgtgcccgt catgcccagc ctggatgagc tgaatcccaa aagtactgtg gatttgctcc tttttgacgc aggtacatcc tccttcaccg aatccagctc agccaccacg aatagcactg gcaacatctt cgatgagctt ccagtcacaa acggactcca cgcagagccg ccggtcaggc gggacaaccc cttcttcaga agcaagcgct cctacagtct ctcggaactc tccgtcctcc aagccaagtc cgatgctccc acatcgtcga gtttcttcac cggcttgaaa tcacctgccc ccgagcaatt tcagagccgg gaggattttc gaactgcctg gctaaaccac aggaagctgg cccggtcttg ccacgacctg gacttgcttg gccaaagccc tggttggggc cagacccaag ccgtggagac aaacatcgtg tgcaagctgg atagctccgg gggtgctgtc cagcttcctg acaccagcat cagcatccac gtgcccgagg gccacgtcgc ccctggggag acccagcaga tctccatgaa agccctgctg gaccccccgc tggagctcaa cagtgacagg tcctgcagca tcagccctgt gctggaggtc aagctgagca acctggaggt gaaaacctct atcatcttgg agatgaaagt gtcagccgag ataaaaaatg acctttttag caaaagcaca gtgggcctcc agtgcctgag gagcgactcg aaggaagggc catatgtctc cgtcccgctc aactgcagct gtggggacac ggtccaggca cagctgcaca acctggagcc ctgtatgtac gtggctgtcg tggcccatgg cccaagcatc ctctaccctt ccaccgtgtg ggacttcatc aataaaaaag tcacagtggg tctctacggc cctaaacaca tccacccatc cttcaagacg gtagtgacca tttttgggca tgactgtgcc ccaaagacgc tcctggtcag cgaggtcaca cgccaggcac ccaaccctgc cccggtggcc ctgcagctgt gggggaagca ccagttcgtt ttgtccaggc cccaggatct caaggtctgt atgttttcca atatgacgaa ttacgaggtc aaagccagcg agcaggccaa agtggtgcga ggattccagc tgaagctggg caaggtgagc cgcctgatct tccccatcac ctcccagaac cccaacgagc tctctgactt cacgctgcgg gttcaggtga aggacgacca ggaggccatc ctcacccagt tttgtgtcca gactcctcag ccacccccta aaagtgccat caagccttcc gggcaaagga ggtttctcaa gaagaacgaa gtcgggaaaa tcatcctgtc cccgtttgcc accactacaa agtacccgac tttccaggac cgcccggtgt ccagcctcaa gtttggtaag ttgctcaaga ctgtggtgcg gcagaacaag aaccactacc tgctggagta caagaagggc gacgggatcg ccctgctcag cgaggagcgg gtcaggctcc ggggccagct gtggaccaag gagtggtaca tcggctacta ccagggcagg gtgggcctcg tgcacaccaa gaacgtgctg gtggtcggca gggcccggcc cagcctgtgc tcgggccccg agctgagcac ctcggtgctg ctggagcaga tcctgcggcc ctgcaaattc ctcacgtaca tctatgcctc cgtgaggacc ctgctcatgg agaacatcag cagctggcgc tccttcgctg acgccctggg ctacgtgaac ctgccgctca cctttttctg ccgggcagag ctggatagtg agcccgagcg ggtggcgtcc gtcctagaaa agctgaagga ggactgtaac aacactgaga acaaagaacg gaagtccttc cagaaggagc ttgtgatggc cctactgaag atggactgcc agggcctggt ggtcagactc atccaggact ttgtgctcct gaccacggct gtagaggtgg cccagcgctg gcgggagctg gctgagaagc tggccaaggt ctccaagcag cagatggacg cctacgagtc tccccaccgg gacaggaacg gggttgtgga cagcgaggcc atgtggaagc ctgcgtatga cttcttactc acctggagcc atcagatcgg ggacagctac cgggatgtca tccaggagct gcacctgggc ctggacaaga tgaaaaaccc catcaccaag cgctggaagc acctcactgg gactctgatc ttggtgaact ccctggacgt tctgagagca gccgccttca gccctgcgga ccaggacgac ttcgtgattt ga. It is sometimes possible for the material contained within the vial of "SH3BP4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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