SALL4 cdna clone
SALL4 cDNA Clone
Gene Names
SALL4; DRRS; HSAL4; ZNF797
Synonyms
SALL4; SALL4 cDNA Clone; SALL4 cdna clone
Sequence
ATGTCGAGGCGCAAGCAGGCGAAACCCCAGCACATCAACTCGGAGGAGGACCAGGGCGAGCAGCAGCCGCAGCAGCAGACCCCGGAGTTTGCAGATGCGGCCCCAGCGGCGCCCGCGGCGGGGGAGCTGGGTGCTCCAGTGAACCACCCAGGGAATGACGAGGTGGCGAGTGAGGATGAAGCCACAGTAAAGCGGCTTCGTCGGGAGGAGACGCACGTCTGTGAGAAATGCTGTGCGGAGTTCTTCAGCATCTCTGAGTTCCTGGAACATAAGAAAAATTGCACTAAAAATCCACCTGTCCTCATCATGAATGACAGCGAGGGGCCTGTGCCTTCAGAAGACTTCTCCGGAGCTGTACTGAGCCACCAGCCCACCAGTCCCGGCAGTAAGGACTGTCACAGGGAGAATGGCGGCAGCTCAGAGGACATGAAGGAGAAGCCGGATGCGGAGTCTGTGGTGTACCTAAAGACAGAGACAGCCCTGCCACCCACCCCCCAGGACATAAGCTATTTAGCCAAAGGCAAAGTGGCCAACACTAACGTGACCTTGCAGGCACTACGGGGCACCAAGGTGGCGGTGAATCAGCGGAGCGCGGATGCACTCCCTGCCCCCGTGCCTGGTGCCAACAGCATCCCGTGGGTCCTCGAGCAGATCTTGTGTCTGCAGCAGCAGCAGCTACAGCAGATCCAGCTCACCGAGCAGATCCGCATCCAGGTGAACATGTGGGCCTCCCACGCCCTCCACTCAAGCGGGGCAGGGGCCGACACTCTGAAGACCTTGGGCAGCCACATGTCTCAGCAGGTTTCTGCAGCTGTGGCTTTGCTCAGCCAGAAAGCTGGAAGCCAAGGTCTGTCTCTGGATGCCTTGAAACAAGCCAAGCTACCTCACGCCAACATCCCTTCTGCCACCAGCTCCCTGTCCCCAGGGCTGGCACCCTTCACTCTGAAGCCGGATGGGACCCGGGTGCTCCCGAACGTCATGTCCCGCCTCCCGAGCGCTTTGCTTCCTCAGGCCCCGGGCTCGGTGCTCTTCCAGAGCCCTTTCTCCACTGTGGCACTAGACACATCCAAGAAAGGGAAGGGGAAGCCACCGAACATCTCCGCGGTGGATGTCAAACCCAAAGACGAGGCGGCCCTCTACAAGCACAAGTGTAAGTACTGTAGCAAGGTTTTTGGGACTGATAGCTCCTTGCAGATCCACCTCCGCTCCCACACTGGAGAGAGACCCTTCGTGTGCTCTGTCTGTGGTCATCGCTTCACCACCAAGGGCAACCTCAAGGTGCACTTTCACCGACATCCCCAGGTGAAGGCAAACCCCCAGCTGTTTGCCGAGTTCCAGGACAAAGTGGCGGCCGGCAATGGCATCCCCTATGCACTCTCTGTACCTGACCCCATAGATGAACCGAGTCTTTCTTTAGACAGCAAACCTGTCCTTGTAACCACCTCTGTAGGGCTACCTCAGAATCTTTCTTCGGGGACTAATCCCAAGGACCTCACGGGTGGCTCCTTGCCCGGTGACCTGCAGCCTGGGCCTTCTCCAGAAAGTGAGGGTGGACCCACACTCCCTGGGGTGGGACCAAACTATAATTCCCCAAGGGCTGGTGGCTTCCAAGGGAGTGGGACCCCTGAGCCAGGGTCAGAGACCCTGAAATTGCAGCAGTTGGTGGAGAACATTGACAAGGCCACCACTGATCCCAACGAATGTCTCATTTGCCACCGAGTCTTAAGCTGTCAGAGCTCCCTCAAGATGCATTATCGCACCCACACCGGGGAGAGACCGTTCCAGTGTAAGATCTGTGGCCGAGCCTTTTCTACCAAAGGTAACCTGAAGACACACCTTGGGGTTCACCGAACCAACACATCCATTAAGACGCAGCATTCGTGCCCCATCTGCCAGAAGAAGTTCACTAATGCCGTGATGCTGCAGCAACATATTCGGATGCACATGGGCGGTCAGATTCCCAACACGCCCCTGCCAGAGAATCCCTGTGACTTTACGGGTTCTGAGCCAATGACCGTGGGTGAGAACGGCAGCACCGGCGCTATCTGCCATGATGATGTCATCGAAAGCATCGATGTAGAGGAAGTCAGCTCCCAGGAGGCTCCCAGCAGCTCCTCCAAGGTCCCCACGCCTCTTCCCAGCATCCACTCGGCATCACCCACGCTAGGGTTTGCCATGATGGCTTCCTTAGATGCCCCAGGGAAAGTGGGTCCTGCCCCTTTTAACCTGCAGCGCCAGGGCAGCAGAGAAAACGGTTCCGTGGAGAGCGATGGCTTGACCAACGACTCATCCTCGCTGATGGGAGACCAGGAGTATCAGAGCCGAAGCCCAGATATCCTGGAAACCACATCCTTCCAGGCACTCTCCCCGGCCAATAGTCAAGCCGAAAGCATCAAGTCAAAGTCTCCCGATGCTGGGAGCAAAGCAGAGAGCTCCGAGAACAGCCGCACTGAGATGGAAGGTCGGAGCAGTCTCCCTTCCACGTTTATCCGAGCCCCGCCGACCTATGTCAAGGTTGAAGTTCCTGGCACATTTGTGGGACCCTCGACATTGTCCCCAGGGATGACCCCTTTGTTAGCAGCCCAGCCACGCCGACAGGCCAAGCAACATGGCTGCACACGGTGTGGGAAGAACTTCTCCTCTGCTAGCGCTCTTCAGATCCACGAGCGGACTCACACTGGAGAGAAGCCTTTTGTGTGCAACATTTGTGGGCGAGCTTTTACCACCAAAGGCAACTTAAAGGTTCACTACATGACACACGGGGCGAACAATAACTCAGCCCGCCGTGGAAGGAAGTTGGCCATCGAGAACACCATGGCTCTGTTAGGTACGGACGGAAAAAGAGTCTCAGAAATCTTTCCCAAGGAAATCCTGGCCCCTTCAGTGAATGTGGACCCTGTTGTGTGGAACCAGTACACCAGCATGCTCAATGGCGGTCTGGCCGTGAAGACCAATGAGATCTCTGTGATCCAGAGTGGGGGGGTTCCTACCCTCCCGGTTTCCTTGGGGGCCACCTCCGTTGTGAATAACGCCACTGTCTCCAAGATGGATGGCTCCCAGTCGGGTATCAGTGCAGATGTGGAAAAACCAAGTGCTACTGACGGCGTTCCCAAACACCAGTTTCCTCACTTCCTGGAAGAAAACAAGATTGCGGTCAGCTAA
Sequence Length
3162
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
65,708 Da
NCBI Official Full Name
Homo sapiens sal-like 4 (Drosophila), mRNA
NCBI Official Synonym Full Names
spalt like transcription factor 4
NCBI Official Symbol
SALL4
NCBI Official Synonym Symbols
DRRS; HSAL4; ZNF797
NCBI Protein Information
sal-like protein 4
UniProt Protein Name
Sal-like protein 4
Protein Family
UniProt Gene Name
SALL4
UniProt Synonym Gene Names
ZNF797
UniProt Entry Name
SALL4_HUMAN
NCBI Description
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Uniprot Description
SALL4: a transcription factor and oncofetal protein expressed embryonically and in the testis. Plays a key role in maintenance and self-renewal of embryonic stem cells. Interacts with NANOG and OCT4. Ectopically expressed in acute B-cell lymphoblastic leukemia (B-ALL) and myeloid leukemia (AML), playing a role in the survival of B-ALL cells and in myeloid leukemogenesis. Aberrantly expressed in multiple carcinomas including human gastric carcinoma and hepatocellular carcinoma. Maintains the stem cell qualities of EpCAM-positive hepatocellular carcinoma cells. Expressed in primary human endometrial cancer samples but not normal or hyperplastic endometrial cells. Its expression in carcinomas positively correlates with metastatic potential and poor patient survival. Specifically binds the c-Myc promoter region in endometrial cancer cells, apparently increasing c-Myc expression. Belongs to the sal C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Cancer Testis Antigen (CTA); C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 20q13.2
Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: multicellular organismal development; regulation of transcription, DNA-dependent; signal transduction; somatic stem cell maintenance; transcription from RNA polymerase II promoter
Disease: Duane-radial Ray Syndrome; Ivic Syndrome
Research Articles on SALL4
Similar Products
Product Notes
The SALL4 sall4 (Catalog #AAA1278520) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTCGAGGC GCAAGCAGGC GAAACCCCAG CACATCAACT CGGAGGAGGA CCAGGGCGAG CAGCAGCCGC AGCAGCAGAC CCCGGAGTTT GCAGATGCGG CCCCAGCGGC GCCCGCGGCG GGGGAGCTGG GTGCTCCAGT GAACCACCCA GGGAATGACG AGGTGGCGAG TGAGGATGAA GCCACAGTAA AGCGGCTTCG TCGGGAGGAG ACGCACGTCT GTGAGAAATG CTGTGCGGAG TTCTTCAGCA TCTCTGAGTT CCTGGAACAT AAGAAAAATT GCACTAAAAA TCCACCTGTC CTCATCATGA ATGACAGCGA GGGGCCTGTG CCTTCAGAAG ACTTCTCCGG AGCTGTACTG AGCCACCAGC CCACCAGTCC CGGCAGTAAG GACTGTCACA GGGAGAATGG CGGCAGCTCA GAGGACATGA AGGAGAAGCC GGATGCGGAG TCTGTGGTGT ACCTAAAGAC AGAGACAGCC CTGCCACCCA CCCCCCAGGA CATAAGCTAT TTAGCCAAAG GCAAAGTGGC CAACACTAAC GTGACCTTGC AGGCACTACG GGGCACCAAG GTGGCGGTGA ATCAGCGGAG CGCGGATGCA CTCCCTGCCC CCGTGCCTGG TGCCAACAGC ATCCCGTGGG TCCTCGAGCA GATCTTGTGT CTGCAGCAGC AGCAGCTACA GCAGATCCAG CTCACCGAGC AGATCCGCAT CCAGGTGAAC ATGTGGGCCT CCCACGCCCT CCACTCAAGC GGGGCAGGGG CCGACACTCT GAAGACCTTG GGCAGCCACA TGTCTCAGCA GGTTTCTGCA GCTGTGGCTT TGCTCAGCCA GAAAGCTGGA AGCCAAGGTC TGTCTCTGGA TGCCTTGAAA CAAGCCAAGC TACCTCACGC CAACATCCCT TCTGCCACCA GCTCCCTGTC CCCAGGGCTG GCACCCTTCA CTCTGAAGCC GGATGGGACC CGGGTGCTCC CGAACGTCAT GTCCCGCCTC CCGAGCGCTT TGCTTCCTCA GGCCCCGGGC TCGGTGCTCT TCCAGAGCCC TTTCTCCACT GTGGCACTAG ACACATCCAA GAAAGGGAAG GGGAAGCCAC CGAACATCTC CGCGGTGGAT GTCAAACCCA AAGACGAGGC GGCCCTCTAC AAGCACAAGT GTAAGTACTG TAGCAAGGTT TTTGGGACTG ATAGCTCCTT GCAGATCCAC CTCCGCTCCC ACACTGGAGA GAGACCCTTC GTGTGCTCTG TCTGTGGTCA TCGCTTCACC ACCAAGGGCA ACCTCAAGGT GCACTTTCAC CGACATCCCC AGGTGAAGGC AAACCCCCAG CTGTTTGCCG AGTTCCAGGA CAAAGTGGCG GCCGGCAATG GCATCCCCTA TGCACTCTCT GTACCTGACC CCATAGATGA ACCGAGTCTT TCTTTAGACA GCAAACCTGT CCTTGTAACC ACCTCTGTAG GGCTACCTCA GAATCTTTCT TCGGGGACTA ATCCCAAGGA CCTCACGGGT GGCTCCTTGC CCGGTGACCT GCAGCCTGGG CCTTCTCCAG AAAGTGAGGG TGGACCCACA CTCCCTGGGG TGGGACCAAA CTATAATTCC CCAAGGGCTG GTGGCTTCCA AGGGAGTGGG ACCCCTGAGC CAGGGTCAGA GACCCTGAAA TTGCAGCAGT TGGTGGAGAA CATTGACAAG GCCACCACTG ATCCCAACGA ATGTCTCATT TGCCACCGAG TCTTAAGCTG TCAGAGCTCC CTCAAGATGC ATTATCGCAC CCACACCGGG GAGAGACCGT TCCAGTGTAA GATCTGTGGC CGAGCCTTTT CTACCAAAGG TAACCTGAAG ACACACCTTG GGGTTCACCG AACCAACACA TCCATTAAGA CGCAGCATTC GTGCCCCATC TGCCAGAAGA AGTTCACTAA TGCCGTGATG CTGCAGCAAC ATATTCGGAT GCACATGGGC GGTCAGATTC CCAACACGCC CCTGCCAGAG AATCCCTGTG ACTTTACGGG TTCTGAGCCA ATGACCGTGG GTGAGAACGG CAGCACCGGC GCTATCTGCC ATGATGATGT CATCGAAAGC ATCGATGTAG AGGAAGTCAG CTCCCAGGAG GCTCCCAGCA GCTCCTCCAA GGTCCCCACG CCTCTTCCCA GCATCCACTC GGCATCACCC ACGCTAGGGT TTGCCATGAT GGCTTCCTTA GATGCCCCAG GGAAAGTGGG TCCTGCCCCT TTTAACCTGC AGCGCCAGGG CAGCAGAGAA AACGGTTCCG TGGAGAGCGA TGGCTTGACC AACGACTCAT CCTCGCTGAT GGGAGACCAG GAGTATCAGA GCCGAAGCCC AGATATCCTG GAAACCACAT CCTTCCAGGC ACTCTCCCCG GCCAATAGTC AAGCCGAAAG CATCAAGTCA AAGTCTCCCG ATGCTGGGAG CAAAGCAGAG AGCTCCGAGA ACAGCCGCAC TGAGATGGAA GGTCGGAGCA GTCTCCCTTC CACGTTTATC CGAGCCCCGC CGACCTATGT CAAGGTTGAA GTTCCTGGCA CATTTGTGGG ACCCTCGACA TTGTCCCCAG GGATGACCCC TTTGTTAGCA GCCCAGCCAC GCCGACAGGC CAAGCAACAT GGCTGCACAC GGTGTGGGAA GAACTTCTCC TCTGCTAGCG CTCTTCAGAT CCACGAGCGG ACTCACACTG GAGAGAAGCC TTTTGTGTGC AACATTTGTG GGCGAGCTTT TACCACCAAA GGCAACTTAA AGGTTCACTA CATGACACAC GGGGCGAACA ATAACTCAGC CCGCCGTGGA AGGAAGTTGG CCATCGAGAA CACCATGGCT CTGTTAGGTA CGGACGGAAA AAGAGTCTCA GAAATCTTTC CCAAGGAAAT CCTGGCCCCT TCAGTGAATG TGGACCCTGT TGTGTGGAAC CAGTACACCA GCATGCTCAA TGGCGGTCTG GCCGTGAAGA CCAATGAGAT CTCTGTGATC CAGAGTGGGG GGGTTCCTAC CCTCCCGGTT TCCTTGGGGG CCACCTCCGT TGTGAATAAC GCCACTGTCT CCAAGATGGA TGGCTCCCAG TCGGGTATCA GTGCAGATGT GGAAAAACCA AGTGCTACTG ACGGCGTTCC CAAACACCAG TTTCCTCACT TCCTGGAAGA AAACAAGATT GCGGTCAGCT AA. It is sometimes possible for the material contained within the vial of "SALL4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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