RNF130 cdna clone
RNF130 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
RNF130: May have a role during the programmed cell death of hematopoietic cells. Acts as an E3 ubiquitin- protein ligase.
Protein type: Ubiquitin ligase; EC 6.3.2.19; Membrane protein, integral; Ligase; EC 6.3.2.-; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 5q35.3
Cellular Component: cytoplasm; nucleus
Molecular Function: ubiquitin-protein ligase activity
Biological Process: programmed cell death
Research Articles on RNF130
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Product Notes
The RNF130 rnf130 (Catalog #AAA1269708) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGACTCATC CAGGCACTGG AGATATTATT GCTGTCATGA TAACAGAATT GAGGGGTAAG GATATTTTGA GTTATCTGGA GAAAAACATC TCTGTACAAA TGACAATAGC TGTTGGAACT CGAATGCCAC CGAAGAACTT CAGCCGTGGC TCTCTAGTCT TCGTGTCAAT ATCCTTTATT GTTTTGATGA TTATTTCTTC AGCATGGCTC ATATTCTACT TCATTCAGAA GATCAGGTAC ACAAATGCAC GCGACAGGAA CCAGCGTCGT CTCGGAGATG CAGCCAAGAA AGCCATCAGT AAATTGACAA CCAGGACAGT AAAGAAGGGT GACAAGGAAA CTGACCCAGA CTTTGATCAT TGTGCAGTCT GCATAGAGAG CTATAAGCAG AATGATGTCG TCCGAATTCT CCCCTGCAAG CATGTTTTCC ACAAATCCTG CGTGGATCCC TGGCTTAGTG AACATTGTAC CTGTCCTATG TGCAAACTTA ATATATTGAA GGCCCTGGGA ATTGTGCCGA ATTTGCCATG TACTGATAAC GTAGCATTCG ATATGGAAAG GCTCACCAGA ACCCAAGCTG TTAACCGAAG ATCAGCCCTC GGCGACCTCG CCGGCGACAA CTCCCTTGGC CTTGAGCCAC TTCGAACTTC GGGGATCTCA CCTCTTCCTC AGGATGGGGA GCTCACTCCG AGAACAGGAG AAATTAACAT TGCAGTAACA AAAGAATGGT TTATTATTGC CAGTTTTGGC CTCCTCAGTG CCCTCACACT CTGCTACATG ATCATCAGAG CCACAGCTAG CTTGAATGCT AATGAGGTAG AATGGTTTTG A. It is sometimes possible for the material contained within the vial of "RNF130, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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