RGS13 cdna clone
RGS13 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
Uniprot Description
RGS13: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)- alpha.
Protein type: GAPs; GAPs, RGS
Chromosomal Location of Human Ortholog: 1q31.2
Cellular Component: cytoplasm; plasma membrane
Molecular Function: GTPase activator activity
Research Articles on RGS13
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Product Notes
The RGS13 rgs13 (Catalog #AAA1267528) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagcaggc ggaattgttg gatttgtaag atgtgcagag atgaatctaa gaggccccct tcaaacctta ctttggagga agtattacag tgggcccagt cttttgaaaa tttaatggct acaaaatatg gtccagtagt ctatgcagca tatttaaaaa tggagcacag tgacgagaat attcaattct ggatggcatg tgaaacctat aagaaaattg cctcacggtg gagcagaatt tctagggcaa agaagcttta taagatttac atccagccac agtcccctag agagattaac attgacagtt cgacaagaga gactatcatc aggaacattc aggaacccac tgaaacatgt tttgaagaag ctcagaaaat agtctatatg catatggaaa gggattccta ccccagattt ctaaagtcag aaatgtacca aaaacttttg aaaactatgc agtccaacaa cagtttctga. It is sometimes possible for the material contained within the vial of "RGS13, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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