REV1 cdna clone
REV1 cDNA Clone
Gene Names
REV1; REV1L; AIBP80
Synonyms
REV1; REV1 cDNA Clone; REV1 cdna clone
Sequence
atgaggcgaggtggatggaggaagcgagctgaaaatgatggctgggaaacatggggtgggtatatggctgccaaggtccagaaattggaggaacagtttcgatcagatgctgctatgcagaaggatgggacttcatctacaatttttagtggagttgccatctatgttaatggatacacagatccttccgctgaggaattgagaaaactaatgatgttgcatggaggtcaataccatgtatattattccagatctaaaacaacacatattattgccacaaatcttcccaatgccaaaattaaagaattaaagggggaaaaagtaattcgaccagaatggattgtggaaagcatcaaagctggacgactcctctcctacattccatatcagctgtacaccaagcagtccagtatgcagaaaggtctcagctttaatcctgtatgcagacctgaggatcctctgccaggtccaagcaatatagccaaacagctcaacaacagggtaaatcacatcgttaagaagattgaaacggaaaatgaagtcaaagtcaatggcatgaacagttggaatgaagaagatgaaaataatgattttagttttgtggatctggagcagacctctccgggaaggaaacagaatggaattccgcatcccagagggagcactgccatttttaatggacacactcctagctctaatggtgccttaaagacacaggattgcttggtgcccatggtcaacagtgttgccagcaggctttctccagcctcttcccaggaggaggataaggctgagaagagcagcactgatttcagagactgcactctgcagcagttgcagcaaagcaccagaaacacagatgctttgcggaatccacacagaactaattctttctcattatcacctttgcacagtaacactaaaatcaatggtgctcaccactccactgttcaggggccttcaagcacaaaaagcacttcttcagtatctacgtttagcaaggcagcaccttcagtgccatccaaaccttcagactgcaattttatttcaaacttctattctcattcaagactgcatcacatatcaatgtggaagtgtgaattgactgagtttgtcaataccctacaaagacaaagtaatggtatctttccaggaagggaaaagttaaaaaaaatgaaaacaggcaggtctgcacttgttgtaactgacacaggagatatgtcagtattgaattctcccagacatcagagctgtataatgcatgttgatatggattgcttctttgtatcagtgggtatacgaaatagaccagatctcaaaggaaaaccagtggctgttacaagtaacagaggcacaggaagggcacctttacgtcctggcgctaacccccagctggagtggcagtattaccagaataaaatcctgaaaggcaaagcagatataccagattcatcattgtgggagaatccagattctgcgcaagcaaatggaattgattctgttttgtcaagggctgaaattgcatcttgtagttatgaggccaggcaacttggcattaagaacggaatgttttttgggcatgctaaacaactatgtcctaatcttcaagctgttccatacgattttcatgcatataaggaagtcgcacaaacattgtatgaaacattggcaagctacactcataacattgaagctgtcagttgtgatgaagcgctggtagacattaccgaaatccttgcagagaccaaacttactcctgatgaatttgcaaatgctgttcgtatggaaatcaaagaccagacgaaatgtgctgcctctgttggaattggttctaatattctcctggctagaatggcaactagaaaagcaaaaccagatgggcagtaccacctaaaaccagaagaagtagatgattttatcagaggccagctagtgaccaatctaccaggagttggacattcaatggaatctaagttggcatctttgggaattaaaacttgtggagacttgcagtatatgaccatggcaaaactccaaaaagaatttggtcccaaaacaggtcagatgctttataggttctgccgtggcttggatgatagaccagttcgaactgaaaaggaaagaaaatctgtttcagctgagatcaactatggaataaggtttactcagccaaaagaggcagaagcttttcttctgagtctttcagaagaaattcaaagaagactagaagccactggcatgaagggtaaacgtctaactctcaaaatcatggtacgaaagcctggggctcctgtagaaactgcaaaatttggaggccatggaatttgtgataacattgccaggactgtaactcttgaccaggcaacagataatgcaaaaataattggaaaggcgatgctaaacatgtttcatacaatgaaactaaatatatcagatatgagaggggttgggattcacgtgaatcagttggttccaactaatctgaacccttccacatgtcccagtcgcccatcagttcagtcaagccactttcctagtgggtcatactctgtccgtgatgtcttccaagttcagaaagctaagaaatccaccgaagaggagcacaaagaagtatttcgggctgctgtggatctggaaatatcatctgcttctagaacttgcactttcttgccaccttttcctgcacatctgccgaccagtcctgatactaacaaggctgagtcttcagggaaatggaatggtctacatactcctgtcagtgtgcagtcgagacttaacctgagtatagaggtcccgtcaccttcccagctggatcagtctgttttagaagcacttccacctgatctccgggaacaagtagagcaagtctgtgctgtccagcaagcagagtcacatggcgacaaaaagaaagaaccagtaaatggctgtaatacaggaattttgccacaaccagttgggacagtcttgttgcaaataccagaacctcaagaatcgaacagtgacgcaggaataaatttaatagcccttccagcattttcacaggtggaccctgaggtatttgctgcccttcctgctgaacttcagagggagctgaaagcagcgtatgatcaaagacaaaggcagggcgagaacagcactcaccagcagtcagccagcgcatctgtgccaaagaatcctttacttcatctaaaggcagcagtgaaagaaaagaaaagaaacaagaagaaaaaaaccatcggttcaccaaaaaggattcagagtcctttgaataacaagctgcttaacagtcctgcaaaaactctgccaggggcctgtggcagtccccagaagttaattgatgggtttctaaaacatgaaggacctcctgcagagaaacccctggaagaactctctgcttctacttcaggtgtgccaggcctttctagtttgcagtctgacccagctggctgtgtgagacctccagcacccaatctagctggagctgttgaattcaatgatgtgaagaccttgctcagagaatggataactacaatttcagatccaatggaagaagacattctccaagttgtgaaatactgtactgatctaatagaagaaaaagatttggaaaaactggatctagttataaaatacatgaaaaggctgatgcagcaatcggtggaatcggtttggaatatggcatttgactttattcttgacaatgtccaggtggttttacaacaaacttatggaagcacattaaaagttacataa
Sequence Length
3753
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
43,649 Da
NCBI Official Full Name
Homo sapiens REV1 homolog (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
REV1, DNA directed polymerase
NCBI Official Symbol
REV1
NCBI Official Synonym Symbols
REV1L; AIBP80
NCBI Protein Information
DNA repair protein REV1
UniProt Protein Name
DNA repair protein REV1
Protein Family
UniProt Gene Name
REV1
UniProt Synonym Gene Names
REV1L; AIBP80
UniProt Entry Name
REV1_HUMAN
NCBI Description
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]
Uniprot Description
REV1L: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Belongs to the DNA polymerase type-Y family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.7.-; Transferase; DNA repair, damage
Chromosomal Location of Human Ortholog: 2q11.1-q11.2
Cellular Component: nucleoplasm
Molecular Function: deoxycytidyl transferase activity; protein binding
Biological Process: bypass DNA synthesis; DNA replication; error-prone postreplication DNA repair; response to UV
Research Articles on REV1
Similar Products
Product Notes
The REV1 rev1 (Catalog #AAA1268234) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaggcgag gtggatggag gaagcgagct gaaaatgatg gctgggaaac atggggtggg tatatggctg ccaaggtcca gaaattggag gaacagtttc gatcagatgc tgctatgcag aaggatggga cttcatctac aatttttagt ggagttgcca tctatgttaa tggatacaca gatccttccg ctgaggaatt gagaaaacta atgatgttgc atggaggtca ataccatgta tattattcca gatctaaaac aacacatatt attgccacaa atcttcccaa tgccaaaatt aaagaattaa agggggaaaa agtaattcga ccagaatgga ttgtggaaag catcaaagct ggacgactcc tctcctacat tccatatcag ctgtacacca agcagtccag tatgcagaaa ggtctcagct ttaatcctgt atgcagacct gaggatcctc tgccaggtcc aagcaatata gccaaacagc tcaacaacag ggtaaatcac atcgttaaga agattgaaac ggaaaatgaa gtcaaagtca atggcatgaa cagttggaat gaagaagatg aaaataatga ttttagtttt gtggatctgg agcagacctc tccgggaagg aaacagaatg gaattccgca tcccagaggg agcactgcca tttttaatgg acacactcct agctctaatg gtgccttaaa gacacaggat tgcttggtgc ccatggtcaa cagtgttgcc agcaggcttt ctccagcctc ttcccaggag gaggataagg ctgagaagag cagcactgat ttcagagact gcactctgca gcagttgcag caaagcacca gaaacacaga tgctttgcgg aatccacaca gaactaattc tttctcatta tcacctttgc acagtaacac taaaatcaat ggtgctcacc actccactgt tcaggggcct tcaagcacaa aaagcacttc ttcagtatct acgtttagca aggcagcacc ttcagtgcca tccaaacctt cagactgcaa ttttatttca aacttctatt ctcattcaag actgcatcac atatcaatgt ggaagtgtga attgactgag tttgtcaata ccctacaaag acaaagtaat ggtatctttc caggaaggga aaagttaaaa aaaatgaaaa caggcaggtc tgcacttgtt gtaactgaca caggagatat gtcagtattg aattctccca gacatcagag ctgtataatg catgttgata tggattgctt ctttgtatca gtgggtatac gaaatagacc agatctcaaa ggaaaaccag tggctgttac aagtaacaga ggcacaggaa gggcaccttt acgtcctggc gctaaccccc agctggagtg gcagtattac cagaataaaa tcctgaaagg caaagcagat ataccagatt catcattgtg ggagaatcca gattctgcgc aagcaaatgg aattgattct gttttgtcaa gggctgaaat tgcatcttgt agttatgagg ccaggcaact tggcattaag aacggaatgt tttttgggca tgctaaacaa ctatgtccta atcttcaagc tgttccatac gattttcatg catataagga agtcgcacaa acattgtatg aaacattggc aagctacact cataacattg aagctgtcag ttgtgatgaa gcgctggtag acattaccga aatccttgca gagaccaaac ttactcctga tgaatttgca aatgctgttc gtatggaaat caaagaccag acgaaatgtg ctgcctctgt tggaattggt tctaatattc tcctggctag aatggcaact agaaaagcaa aaccagatgg gcagtaccac ctaaaaccag aagaagtaga tgattttatc agaggccagc tagtgaccaa tctaccagga gttggacatt caatggaatc taagttggca tctttgggaa ttaaaacttg tggagacttg cagtatatga ccatggcaaa actccaaaaa gaatttggtc ccaaaacagg tcagatgctt tataggttct gccgtggctt ggatgataga ccagttcgaa ctgaaaagga aagaaaatct gtttcagctg agatcaacta tggaataagg tttactcagc caaaagaggc agaagctttt cttctgagtc tttcagaaga aattcaaaga agactagaag ccactggcat gaagggtaaa cgtctaactc tcaaaatcat ggtacgaaag cctggggctc ctgtagaaac tgcaaaattt ggaggccatg gaatttgtga taacattgcc aggactgtaa ctcttgacca ggcaacagat aatgcaaaaa taattggaaa ggcgatgcta aacatgtttc atacaatgaa actaaatata tcagatatga gaggggttgg gattcacgtg aatcagttgg ttccaactaa tctgaaccct tccacatgtc ccagtcgccc atcagttcag tcaagccact ttcctagtgg gtcatactct gtccgtgatg tcttccaagt tcagaaagct aagaaatcca ccgaagagga gcacaaagaa gtatttcggg ctgctgtgga tctggaaata tcatctgctt ctagaacttg cactttcttg ccaccttttc ctgcacatct gccgaccagt cctgatacta acaaggctga gtcttcaggg aaatggaatg gtctacatac tcctgtcagt gtgcagtcga gacttaacct gagtatagag gtcccgtcac cttcccagct ggatcagtct gttttagaag cacttccacc tgatctccgg gaacaagtag agcaagtctg tgctgtccag caagcagagt cacatggcga caaaaagaaa gaaccagtaa atggctgtaa tacaggaatt ttgccacaac cagttgggac agtcttgttg caaataccag aacctcaaga atcgaacagt gacgcaggaa taaatttaat agcccttcca gcattttcac aggtggaccc tgaggtattt gctgcccttc ctgctgaact tcagagggag ctgaaagcag cgtatgatca aagacaaagg cagggcgaga acagcactca ccagcagtca gccagcgcat ctgtgccaaa gaatccttta cttcatctaa aggcagcagt gaaagaaaag aaaagaaaca agaagaaaaa aaccatcggt tcaccaaaaa ggattcagag tcctttgaat aacaagctgc ttaacagtcc tgcaaaaact ctgccagggg cctgtggcag tccccagaag ttaattgatg ggtttctaaa acatgaagga cctcctgcag agaaacccct ggaagaactc tctgcttcta cttcaggtgt gccaggcctt tctagtttgc agtctgaccc agctggctgt gtgagacctc cagcacccaa tctagctgga gctgttgaat tcaatgatgt gaagaccttg ctcagagaat ggataactac aatttcagat ccaatggaag aagacattct ccaagttgtg aaatactgta ctgatctaat agaagaaaaa gatttggaaa aactggatct agttataaaa tacatgaaaa ggctgatgca gcaatcggtg gaatcggttt ggaatatggc atttgacttt attcttgaca atgtccaggt ggttttacaa caaacttatg gaagcacatt aaaagttaca taa. It is sometimes possible for the material contained within the vial of "REV1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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