RASGRF2 cdna clone
RASGRF2 cDNA Clone
Gene Names
RASGRF2; GRF2; RAS-GRF2
Synonyms
RASGRF2; RASGRF2 cDNA Clone; RASGRF2 cdna clone
Sequence
atgcagaagagcgtgcgctacaacgaggggcacgccctgtacctggcctttctggcgcgcaaggagggcaccaagcgcggcttcctgagtaagaagacggccgaggcgagccgctggcacgagaagtggttcgccctctaccagaatgtgctcttctacttcgagggcgagcagagctgccgcccggcgggcatgtacctcctggagggctgcagctgcgaacgaacgcccgcgccacccagggccggcgccgggcagggaggcgtccgagacgcgctggacaagcagtattactttactgttctttttggccatgaaggtcagaagccactggagctgcgctgtgaggaggagcaggatggtaaagagtggatggaggccattcaccaagccagttatgcagacattttgattgagagggaagtattaatgcagaagtacattcatctagttcagatcgtagagacagaaaaaattgcagctaaccaactccgacatcaacttgaagatcaagacacagaaatcgaaaggcttaaatcagagattattgctcttaataaaaccaaagaacgaatgcgaccttaccaaagcaaccaagaagacgaagatccagacatcaagaagattaaaaaggttcagagcttcatgcgaggatggttgtgcagaaggaaatggaagaccatcgtgcaggattacatttgttctcctcatgctgaaagtatgaggaagagaaaccagattgtgttcaccatggtggaggcagagtcagagtacgttcaccagctctacatcctggtcaatggctttctccggcccctgcgtatggccgccagctccaagaagccccccatcagccacgacgacgtcagcagtatttttcttaacagtgaaacaatcatgtttcttcatgaaatatttcatcaaggactaaaggcaaggatagcaaactggcccactttaattttagctgatctgtttgatattttgctccccatgctgaacatttatcaagaatttgtgcgtaatcaccagtacagcctgcaagttctcgccaattgtaagcaaaacagagattttgacaaactcttaaaacagtatgaagccaatccagcctgtgaggggaggatgctggagacattcttgacctatcccatgtttcagatccccagatatatcatcacactccatgagctccttgctcacacaccccatgagcatgtggaaaggaaaagcctggagtttgccaaatcaaagctagaggaactatccagagtaatgcacgatgaagtcagcgacactgaaaacataaggaaaaaccttgccatcgaaagaatgatcgtggagggctgtgacatcttgctggacaccagccaaacgttcatccgccaaggttctcttattcaagtaccttccgttgagagggggaaacttagtaaagttcgcctgggttcgttgtctttgaaaaaggaaggagagagacaatgcttcttatttacaaaacactttttaatatgtacaagaagttcaggagggaagcttcatctgctcaagacaggtggggttctgtctctaatagactgcacattgattgaggagccagatgcaagcgatgatgactctaaaggttctgggcaagtgtttgggcacctggattttaaaatagtggtggagcctcctgacgctgccgccttcactgttgtcttgttagcaccctcacgccaggagaaagctgcctggatgagtgacatcagtcagtgtgtggacaatatacgatgtaatggtttaatgactatagtgtttgaagagaattccaaagtcactgtgccacatatgattaagtctgatgcccgtcttcataaagacgacactgacatttgcttcagtaaaacactcaactcctgcaaagtgccccagatccgttatgccagcgtggagcgcctcttggaacgactgacagacttgcggtttcttagtattgatttcctcaacacctttctgcacacctatcgtattttcactactgccgctgtggtgctggggaaactctccgacatatacaagaggcctttcacctccatccctgtcaggtcattggaattgttttttgctaccagccagaacaacagaggtgaacatttggtggatggcaaatccccacgtctgtgtcgcaaattctcttccccgccaccactggctgtgtccagaacatcttccccagtgagggccagaaagctgtctttgacttctcccttgaactcaaagataggagcattggacctgacaacttccagcagtcccaccaccaccacccagagtcccgctgcgtctccaccaccacacactggtcagataccactggatctcagcagaggcctctcttctccagagcaaagcccgggaacggtagaagagaatgtcgataacccacgcgtggatctgtgtaacaagctaaaacgaagtattcaaaaagcagtcctagagtctgcaccagcggaccgagcaggagtggaaagctcccctgcagcggacaccacagaactttcaccttgcagatccccctcaactcctcggcacctccgctatcgacagcctggaggacagacggcggacaatgcccactgctctgtttcaccggcttctgcttttgcaatagccacagctgcagcaggacatgggagtccaccaggctttaacaacaccgagagaacatgtgataaagagtttattatacggagaacggctaccaatcgagttctgaacgtcctccgtcactgggtctcaaagcacgcacaggatttcgaactcaacaatgaactaaagatgaatgtcctaaatttgctagaagaagttttgcgagacccagaccttcttccccaagaaaggaaagccgccgcgaatatcctcagggccctttcacaagatgaccaagatgacatccacctaaaattagaggatataattcaaatgactgactgcatgaaggccgaatgctttgagtccttgtcggccatggagctggcagaacagatcaccctcctggaccatgtcattttcagaagcattccctacgaggagtttcttgggcaggggtggatgaagctggataaaaacgaaagaactccttacattatgaaaaccagccaacacttcaatgacatgagtaacctggtggcctcccagataatgaactatgctgatgtcagctcccgtgccaacgccatcgagaaatgggtggcagtggcggacatctgccgatgcctgcacaactacaacggcgtgctggagatcacctcggccttaaacagaagtgccatctacaggctgaagaaaacctgggccaaggtctctaagcagacaaaagctctaatggacaaacttcaaaagactgtttcctctgaaggaagatttaaaaatcttagagaaacccttaaaaattgtaaccctcctgcagttccttatcttgggatgtacttgacagacctggcatttattgaagaaggaacaccaaactttactgaggaaggccttgtcaatttctccaaaatgagaatgatatcacacatcatcagagagatacgccagttccagcagacttcctacagaatagatcatcagccaaaggtcgcacagtacttgcttgacaaagaccttatcatagatgaagatacgctatatgagctgtcactaaaaattgaacctcgactccctgcttga
Sequence Length
3714
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
140,764 Da
NCBI Official Full Name
Homo sapiens Ras protein-specific guanine nucleotide-releasing factor 2, mRNA
NCBI Official Synonym Full Names
Ras protein specific guanine nucleotide releasing factor 2
NCBI Official Symbol
RASGRF2
NCBI Official Synonym Symbols
GRF2; RAS-GRF2
NCBI Protein Information
ras-specific guanine nucleotide-releasing factor 2
UniProt Protein Name
Ras-specific guanine nucleotide-releasing factor 2
Protein Family
UniProt Gene Name
RASGRF2
UniProt Synonym Gene Names
GRF2; Ras-GRF2
UniProt Entry Name
RGRF2_HUMAN
NCBI Description
RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
Uniprot Description
RASGRF2: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
Protein type: GEFs; GEFs, Ras
Chromosomal Location of Human Ortholog: 5q13
Cellular Component: cytosol; plasma membrane
Molecular Function: guanyl-nucleotide exchange factor activity; Ras guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity
Biological Process: MAPKKK cascade; positive regulation of apoptosis; regulation of small GTPase mediated signal transduction
Research Articles on RASGRF2
Similar Products
Product Notes
The RASGRF2 rasgrf2 (Catalog #AAA1278395) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagaaga gcgtgcgcta caacgagggg cacgccctgt acctggcctt tctggcgcgc aaggagggca ccaagcgcgg cttcctgagt aagaagacgg ccgaggcgag ccgctggcac gagaagtggt tcgccctcta ccagaatgtg ctcttctact tcgagggcga gcagagctgc cgcccggcgg gcatgtacct cctggagggc tgcagctgcg aacgaacgcc cgcgccaccc agggccggcg ccgggcaggg aggcgtccga gacgcgctgg acaagcagta ttactttact gttctttttg gccatgaagg tcagaagcca ctggagctgc gctgtgagga ggagcaggat ggtaaagagt ggatggaggc cattcaccaa gccagttatg cagacatttt gattgagagg gaagtattaa tgcagaagta cattcatcta gttcagatcg tagagacaga aaaaattgca gctaaccaac tccgacatca acttgaagat caagacacag aaatcgaaag gcttaaatca gagattattg ctcttaataa aaccaaagaa cgaatgcgac cttaccaaag caaccaagaa gacgaagatc cagacatcaa gaagattaaa aaggttcaga gcttcatgcg aggatggttg tgcagaagga aatggaagac catcgtgcag gattacattt gttctcctca tgctgaaagt atgaggaaga gaaaccagat tgtgttcacc atggtggagg cagagtcaga gtacgttcac cagctctaca tcctggtcaa tggctttctc cggcccctgc gtatggccgc cagctccaag aagcccccca tcagccacga cgacgtcagc agtatttttc ttaacagtga aacaatcatg tttcttcatg aaatatttca tcaaggacta aaggcaagga tagcaaactg gcccacttta attttagctg atctgtttga tattttgctc cccatgctga acatttatca agaatttgtg cgtaatcacc agtacagcct gcaagttctc gccaattgta agcaaaacag agattttgac aaactcttaa aacagtatga agccaatcca gcctgtgagg ggaggatgct ggagacattc ttgacctatc ccatgtttca gatccccaga tatatcatca cactccatga gctccttgct cacacacccc atgagcatgt ggaaaggaaa agcctggagt ttgccaaatc aaagctagag gaactatcca gagtaatgca cgatgaagtc agcgacactg aaaacataag gaaaaacctt gccatcgaaa gaatgatcgt ggagggctgt gacatcttgc tggacaccag ccaaacgttc atccgccaag gttctcttat tcaagtacct tccgttgaga gggggaaact tagtaaagtt cgcctgggtt cgttgtcttt gaaaaaggaa ggagagagac aatgcttctt atttacaaaa cactttttaa tatgtacaag aagttcagga gggaagcttc atctgctcaa gacaggtggg gttctgtctc taatagactg cacattgatt gaggagccag atgcaagcga tgatgactct aaaggttctg ggcaagtgtt tgggcacctg gattttaaaa tagtggtgga gcctcctgac gctgccgcct tcactgttgt cttgttagca ccctcacgcc aggagaaagc tgcctggatg agtgacatca gtcagtgtgt ggacaatata cgatgtaatg gtttaatgac tatagtgttt gaagagaatt ccaaagtcac tgtgccacat atgattaagt ctgatgcccg tcttcataaa gacgacactg acatttgctt cagtaaaaca ctcaactcct gcaaagtgcc ccagatccgt tatgccagcg tggagcgcct cttggaacga ctgacagact tgcggtttct tagtattgat ttcctcaaca cctttctgca cacctatcgt attttcacta ctgccgctgt ggtgctgggg aaactctccg acatatacaa gaggcctttc acctccatcc ctgtcaggtc attggaattg ttttttgcta ccagccagaa caacagaggt gaacatttgg tggatggcaa atccccacgt ctgtgtcgca aattctcttc cccgccacca ctggctgtgt ccagaacatc ttccccagtg agggccagaa agctgtcttt gacttctccc ttgaactcaa agataggagc attggacctg acaacttcca gcagtcccac caccaccacc cagagtcccg ctgcgtctcc accaccacac actggtcaga taccactgga tctcagcaga ggcctctctt ctccagagca aagcccggga acggtagaag agaatgtcga taacccacgc gtggatctgt gtaacaagct aaaacgaagt attcaaaaag cagtcctaga gtctgcacca gcggaccgag caggagtgga aagctcccct gcagcggaca ccacagaact ttcaccttgc agatccccct caactcctcg gcacctccgc tatcgacagc ctggaggaca gacggcggac aatgcccact gctctgtttc accggcttct gcttttgcaa tagccacagc tgcagcagga catgggagtc caccaggctt taacaacacc gagagaacat gtgataaaga gtttattata cggagaacgg ctaccaatcg agttctgaac gtcctccgtc actgggtctc aaagcacgca caggatttcg aactcaacaa tgaactaaag atgaatgtcc taaatttgct agaagaagtt ttgcgagacc cagaccttct tccccaagaa aggaaagccg ccgcgaatat cctcagggcc ctttcacaag atgaccaaga tgacatccac ctaaaattag aggatataat tcaaatgact gactgcatga aggccgaatg ctttgagtcc ttgtcggcca tggagctggc agaacagatc accctcctgg accatgtcat tttcagaagc attccctacg aggagtttct tgggcagggg tggatgaagc tggataaaaa cgaaagaact ccttacatta tgaaaaccag ccaacacttc aatgacatga gtaacctggt ggcctcccag ataatgaact atgctgatgt cagctcccgt gccaacgcca tcgagaaatg ggtggcagtg gcggacatct gccgatgcct gcacaactac aacggcgtgc tggagatcac ctcggcctta aacagaagtg ccatctacag gctgaagaaa acctgggcca aggtctctaa gcagacaaaa gctctaatgg acaaacttca aaagactgtt tcctctgaag gaagatttaa aaatcttaga gaaaccctta aaaattgtaa ccctcctgca gttccttatc ttgggatgta cttgacagac ctggcattta ttgaagaagg aacaccaaac tttactgagg aaggccttgt caatttctcc aaaatgagaa tgatatcaca catcatcaga gagatacgcc agttccagca gacttcctac agaatagatc atcagccaaa ggtcgcacag tacttgcttg acaaagacct tatcatagat gaagatacgc tatatgagct gtcactaaaa attgaacctc gactccctgc ttga. It is sometimes possible for the material contained within the vial of "RASGRF2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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