RASAL2 cdna clone
RASAL2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
RASAL2: Inhibitory regulator of the Ras-cyclic AMP pathway.
Protein type: GAPs; GAPs, Ras
Chromosomal Location of Human Ortholog: 1q24
Cellular Component: cytoplasm; cytosol
Molecular Function: protein binding
Biological Process: MAPKKK cascade; negative regulation of Ras protein signal transduction; signal transduction
Research Articles on RASAL2
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Product Notes
The RASAL2 rasal2 (Catalog #AAA1276386) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTTCCCGG CGCTGGAGTC CGACTCGCCG CTGCCCCCGG AGGACCTGGA CGCGGTTGTC CCAGTCAGTG GAGCCGTCGC CGGTGGCATG TTGGATCGGA TCCTTCTGGA GTCCGTGTGC CAGCAACAGA GCTGGGTCCG GGTGTACGAT GTGAAAGGAC CACCCACCCA CCGTCTGTCT TGTGGTCAGT CACCCTACAC CGAGACAACA ACGTGGGAGC GGAAGTATTG CATCCTCACA GACAGCCAGT TGGTATTGCT CAACAAGGAG AAGGAGATAC CTGTGGAAGG GGGACAGGAG CAGCAGACAG ATTCCACCAA AGGGCGATGC CTGAGGAGAA CTGTCAGTGT CCCTTCCGAG GGTCAGTTTC CCGAGTACCC ACCAGAGGGC GCCACTAAAC TGGAGGTACC AGCAGAAAGG TCCCCTCGTA GACGGAGTAT CTCAGGGACC AGTACATCAG AGAAACCCAA CTCCATGGAC ACTGCAAATA CCTCACCCTT CAAAGTACCA GGATTCTTCA GCAAGCGCCT GAAAGGCTCC ATCAAGAGGA CCAAAAGCCA GTCAAAGCTT GACAGAAACA CGAGCTTTCG GCTTCCATCC CTTCGCAGTA CAGATGACAG GTCTCGTGGG CTGCCTAAAC TAAAAGAGTC ACGTTCCCAT GAATCCTTGC TGAGCCCATG CAGCACAGTG GAATGTCTGG ATCTTGGTAG AGGGGAACCT GTATCAGTGA AACCACTTCA TAGTAGCATC CTTGGACAAG ACTTCTGCTT TGAGGTTACC TACTTAAGTG GAAGTAAATG CTTCAGCTGT AATTCTGCTT CTGAGAGAGA CAAGTGGATG GAAAACCTTC GCAGGACAGT TCAACCTAAT AAGGACAATT GCAGGCGAGC TGAAAATGTT CTTCGTTTAT GGATCATTGA AGCCAAGGAC CTTGCCCCTA AAAAGAAATA TTTCTGCGAA CTGTGCCTTG ATGATACCCT CTTTGCTCGT ACAACCAGCA AGACCAAAGC AGACAATATT TTCTGGGGCG AACATTTTGA ATTCTTCAGC CTTCCACCTC TTCATAGTAT CACAGTTCAC ATTTACAAGG ATGTGGAAAA AAAGAAAAAA AAGGACAAGA ATAATTATGT AGGGCTAGTC AACATCCCCA CTGCCAGTGT GACTGGTCGC CAATTTGTAG AAAAGTGGTA TCCAGTGAGT ACACCTACAC CCAACAAAGG AAAGACAGGA GGACCTTCTA TTCGGATTAA ATCACGTTTC CAAACTATCA CCATTCTGCC TATGGAGCAA TACAAAGAAT TTGCAGAATT TGTCACCAGC AACTACACCA TGCTGTGTTC TGTCCTTGAG CCAGTAATTA GTGTGAGAAA TAAAGAGGAG TTGGCTTGTG CCTTAGTGCA CATTCTTCAA AGTACTGGCA GAGCCAAGGA TTTTCTGACT GACTTGGTGA TGTCTGAGGT GGATCGTTGT GGAGAGCATG ATGTCTTGAT CTTCAGAGAG AACACTATTG CCACCAAATC CATTGAGGAA TACCTCAAGT TGGTGGGACA ACAGTATCTT CATGACGCAC TGGGGGAGTT TATCAAAGCT TTGTATGAGT CCGATGAGAA CTGTGAAGTG GATCCCAGCA AATGTTCATC TAGTGAACTG ATAGACCATC AGAGCAACCT GAAAATGTGC TGTGAGCTGG CTTTCTGCAA GATCATCAAC TCTTACTGTG TTTTCCCTCG TGAGTTGAAA GAAGTGTTTG CATCATGGAA GCAGCAGTGC CTGAACCGTG GCAAGCAAGA CATCAGCGAG AGGCTCATCA GTGCCTCATT ATTTCTCCGT TTTCTGTGTC CAGCCATTAT GTCTCCCAGT CTTTTCAACC TTATGCAGGA GTATCCTGAT GACCGCACAT CTCGGACTCT AACTCTTATT GCCAAGGTCA TTCAGAACCT GGCCAACTTT GCCAAGTTTG GTAACAAAGA GGAATACATG GCATTCATGA ATGATTTTTT AGAACATGAA TGGGGTGGAA TGAAGCGCTT TCTTTTGGAG ATCTCTAATC CAGACACCAT CTCAAACACC CCAGGCTTTG ATGGTTACAT TGATCTGGGC CGAGAGCTTT CAGTTTTGCA TTCCTTACTG TGGGAAGTAG TTTCCCAACT TGATAAGGCG ACCGTGGCAA AATTGGGGCC TCTCCCTCGT GTTCTTGCTG ATATTACCAA GTCATTGACT AATCCTACGC CAATACAACA GCAACTGAGA CGCTTCACTG AACATAACTC CAGTCCAAAT GTCAGTGGAA GCCTCTCCTC TGGGCTGCAG AAAATATTTG AAGACCCCAC TGACAGTGAT TTGCATAAAC TAAAATCTCC AAGCCAGGAC AACACAGACA GCTACTTCAG AGGGAAAACA TTATTGCTGG TTCAGCAAGC CTCCTCTCAG AGCATGACTT ATTCTGAAAA GGATGAAAGG GAAAGTAGCC TTCCTAATGG TCGGAGCGTC TCCCTCATGG ACCTCCAGGA CACTCATGCT GCTCAAGTGG AGCATGCATC TGTCATGCTT GATGTGCCTA TACGCTTGAC CGGAAGCCAG CTTTCCATAA CCCAGGTGGC CAGCATCAAA CAGCTGCGGG AAACCCAGAG CACTCCCCAA AGTGCACCCC AAGTGAGAAG GCCCCTGCAC CCAGCCTTGA ACCAGCCAGG TGGCCTTCAG CCCTTGTCGT TCCAGAACCC TGTCTATCAC CTCAATAACC CAATTCCAGC AATGCCAAAG GCCTCTATAG ATTCCAGTTT GGAGAACCTA AGCACTGCCA GTTCCAGAAG CCAAAGTAAC AGTGAAGACT TCAAGCTCAG TGGACCCAGC AATAGCAGCA TGGAAGATTT CACTAAACGT AGCACTCAGA GTGAGGACTT CTCCAGGCGG CACACGGTGC CAGATAGACA CATACCTCTT GCTTTGCCAC GACAAAATAG TACTGGGCAG GCCCAGATCC GAAAAGTGGA CCAGGGTGGG TTAGGTGCCC GAGCCAAAGC CCCACCATCC CTGCCACACA GTGCTTCTTT ACGTAGCACC GGGAGCATGT CAGTGGTGTC CGCAGCCCTG GTGGCCGAAC CTGTGCAGAA TGGGAGCCGG TCCCGGCAGC AGTCCTCTTC CTCCAGAGAG AGCCCTGTTC CCAAAGTTAG AGCAATCCAG AGACAACAGA CACAGCAGGT TCAGTCACCT GTGGACTCTG CCACAATGTC CCCAGTAGAG AGGACAGCAG CCTGGGTTCT GAACAATGGG CAGTATGAAG AGGATGTGGA AGAAACTGAG CAAAATCTAG ATGAAGCCAA GCATGCTGAG AAGTATGAAC AAGAAATTAC TAAACTGAAG GAGCGCCTGA GAGTTTCCAG CCGGCGACTG GAGGAATATG AACGCCGCTT GCTGGTGCAG GAGCAGCAGA TGCAGAAGCT GCTGCTGGAA TACAAGGCCC GACTGGAGGA CAGCGAGGAG CGGCTCCGAA GACAGCAGGA AGAAAAAGAT AGCCAGATGA AAAGCATCAT CAGCAGGCTA ATGGCTGTGG AAGAGGAACT GAAGAAGGAT CATGCTGAGA TGCAAGCAGT TATTGATGCA AAGCAGAAAA TAATTGATGC ACAGGAAAAA CGGATCGTGT CCCTGGATTC AGCCAACACC AGACTGATGA GCGCGCTGAC CCAAGTGAAG GAGCGGTACA GCATGCAGGT CCGCAATGGC ATCTCCCCCA CCAACCCCAC CAAGCTTTCC ATCACGGAGA ATGGTGAATT CAAAAACAGC AGCTGCTGA. It is sometimes possible for the material contained within the vial of "RASAL2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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