QTRTD1 cdna clone
QTRTD1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
QTRTD1: Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.
Protein type: EC 2.4.2.29
Chromosomal Location of Human Ortholog: 3q13.31
Cellular Component: cytoplasm; mitochondrial outer membrane; mitochondrion
Molecular Function: protein heterodimerization activity; protein homodimerization activity; queuine tRNA-ribosyltransferase activity
Biological Process: queuosine biosynthetic process; tRNA modification
Research Articles on QTRTD1
Similar Products
Product Notes
The QTRTD1 qtrtd1 (Catalog #AAA1272051) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaagctga gtcttaccaa ggtagttaat ggctgtcgcc taggaaaaat aaaaaacctg ggcaaaacag gggaccacac catggatatt ccaggctgcc ttctgtatac caagactggc tccgccccac acctcaccca tcacacgctg cataatatcc acggggttcc tgccatggct cagcttacgc tgtcatccct agcagaacat catgaagtct tgacagaata taaagaagga gttggaaagt ttataggcat gccagaatca ctcttgtact gctccctgca cgatccagtc agcccctgcc cggctggtta tgtaacaaac aagtctgtgt ctgtgtggag tgttgcagga cgagtggaaa tgactgtttc caagttcatg gcaattcaga aggcccttca gccagactgg ttccagtgcc tctccgatgg agaagtatct tgtaaggaag caacttccat aaaaagggtc agaaagtctg ttgaccgatc acttcttttc ttggataact gtctgcggct gcaggaagag tcagaggttc ttcagaagag tgtgatcatt ggagtgattg aaggtggaga tgtgatggaa gagaggctga ggtcagcacg agagacagcc aagcggcctg tgggtggctt ccttctggat ggttttcaag gaaatccaac aaccctggag gctagactac gcttgctgtc atcagtcact gcagagctgc cggaggacaa gccaaggctc atatctggtg ttagtcggcc agatgaggtg ctcgagtgta ttgaaagagg agtggactta tttgagagtt ttttccctta tcaagtaaca gagcggggat gtgccctgac tttcagtttt gattaccagc cgaatcctga agagacacta ctacaacaaa atggaacaca agaagaaata aaatgtatgg atcaaataaa gaaaattgaa acaactggtt gcaaccaaga aataacatca tttgaaatta atctgaagga aaaaaagtac caggaggact ttaacccgct ggtgagagga tgttcctgtt actgctgtaa gaatcacact cgggcataca tccaccatct gctggtgacc aatgagctgc tggccggagt cctgcttatg atgcacaact ttgaacacta ctttgggttt ttccattaca tccgggaagc actaaaaagt gacaaactgg cacagttgaa agagctcatc cacaggcaag catcttga. It is sometimes possible for the material contained within the vial of "QTRTD1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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