PTGES3 cdna clone
PTGES3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
Uniprot Description
TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.
Protein type: Nuclear receptor co-regulator; Chaperone; EC 5.3.99.3; Isomerase; Transferase
Chromosomal Location of Human Ortholog: 12q13.3|12
Cellular Component: chromosome, telomeric region; cytoplasm; cytosol; nucleoplasm; nucleus; telomerase holoenzyme complex
Molecular Function: prostaglandin-E synthase activity; protein binding; telomerase activity; unfolded protein binding
Biological Process: cyclooxygenase pathway; prostaglandin biosynthetic process; signal transduction; telomere maintenance
Research Articles on PTGES3
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Product Notes
The PTGES3 ptges3 (Catalog #AAA1274614) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagcctg cttctgcaaa gtggtacgat cgaagggact atgtcttcat tgaattttgt gttgaagaca gtaaggatgt taatgtaaat tttgaaaaat ccaaacttac attcagttgt ctcggaggaa gtgataattt taagcattta aatgaaattg atctttttca ctgtattgat ccaaatgatt ccaagcataa aagaacggac agatcaattt tatgttgttt acgaaaagga gaatctggcc agtcatggcc aaggttaaca aaagaaaggg caaagcttaa ttggcttagt gtcgacttca ataattggaa agactgggaa gatgattcag atgaagacat gtctaatttt gatcgtttct ctgagatgat gaacaacatg ggtggtgatg aggatgtaga tttaccagaa gtagatggag cagatgatga ttcacaagac agtgatgatg aaaaaatgcc agatctggag taa. It is sometimes possible for the material contained within the vial of "PTGES3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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