PTDSS1 cdna clone
PTDSS1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
Uniprot Description
PTDSS1: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. Belongs to the phosphatidyl serine synthase family.
Protein type: EC 2.7.8.29; Transferase; Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 8q22
Cellular Component: endoplasmic reticulum membrane; integral to membrane; membrane
Molecular Function: transferase activity
Biological Process: phosphatidylserine biosynthetic process; phospholipid biosynthetic process
Disease: Lenz-majewski Hyperostotic Dwarfism
Research Articles on PTDSS1
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Product Notes
The PTDSS1 ptdss1 (Catalog #AAA1274880) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgtcct gcgtggggag ccggacccta agcaaggatg atgtgaacta caaaatgcat ttccggatga tcaacgagca gcaagtggag gacatcacca ttgacttctt ctaccggccg cataccatca ccctgctcag cttcaccatc gtcagcctca tgtacttcgc ctttaccagg gatgactctg ttccagaaga caacatctgg agaggcatcc tctctgttat tttcttcttt cttatcatca gtgtgttagc tttccccaat ggtccgttca ctcgacctca tccagcctta tggcgaatgg tttttggact cagtgtgctc tacttcctgt tcctggtatt cctactcttc ctgaatttcg agcaggttaa atctctaatg tattggctag atccaaatct tcgatacgcc acaagggaag cagatgtcat ggagtatgct gtgaactgcc atgtgatcac ctgggagagg attatcagcc actttgatat ttttgcattt ggacatttct ggggctgggc catgaaggcc ttgctgatcc gtagttacgg tctctgctgg acaatcagta ttacctggga gctgactgag ctcttcttca tgcatctcct ccccaatttt gccgagtgct ggtgggatca agtcattctg gacatcctgt tgtgcaatgg cggtggcatt tggctgggca tggtcgtttg ccggttttta gagatgagga cttaccactg ggcaagcttc aaggacattc ataccaccac cgggaagatc aagagagctg ttctgcagtt cactcctgct agctggacct atgttcgatg gtttgacccc aaatcttctt ttcagagagt agctggagtg taccttttca tgatcatctg gcagctgact gagttgaata ccttcttctt gaagcatatc tttgtgttcc aagccagtca tccattaagt tggggtagaa ttctctttat tggtggcatc acagctccca cagtgagaca gtactacgct tacctcaccg acacacagtg caagcgcgta ggaacacaat gctgggtgtt tggggtcatt ggtttcctgg aggccattgt ttgcataaaa tttggacaag atctcttctc taagacccaa atactctatg ttgtgctttg gcttctttgc gtggctttca ccactttcct ctgtctgtac ggcatgattt ggtatgcaga acactatggt caccgagaaa agacctactc ggagtgtgaa gatggcacct acagtccaga gatctcctgg catcacagga aagggacaaa aggttctgaa gacagcccac ccaagcatgc aggcaacaac gaaagccatt cttccaggag aaggaatcgg cattccaagt caaaagtcac caatggcgtt ggaaagaaat ga. It is sometimes possible for the material contained within the vial of "PTDSS1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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