PRUNE cdna clone
PRUNE cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Uniprot Description
PRUNE: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. Belongs to the PPase class C family. Prune subfamily. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleotide Metabolism - purine; EC 3.6.1.1; Hydrolase
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: cytoplasm
Molecular Function: protein binding
Research Articles on PRUNE
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Product Notes
The PRUNE prune (Catalog #AAA1272232) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgctgagaa aagaccagaa gactatctat agacaaggcg tcaaggtggc cattagtgca atatatatgg atttggagat ctgtgaagtc ctggaacgct cccactctcc acccctgaag ctgacccctg cctcaagtac ccaccctaac ctccatgcct atcttcaagg caacacccag gtctctcgaa agaaacttct gcccctgctc caggaagccc tgtcagcata ttttgactcc atgaagatcc cttcaggaca gcctgagaca gcagatgtgt ccagggagca agtggacaag gaattggaca gggcaagtaa ctccctgatt tctggactga gtcaagatga ggaggaccct ccgctgcccc cgacgcccat gaacagcttg gtggatgagt gccctctaga tcaggggctg cctaaactct ctgctgaggc cgtcttcgag aagtgcagtc agatctcact gtcacagtct accacagcct ccctgtccaa gaagtga. It is sometimes possible for the material contained within the vial of "PRUNE, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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