PRDX5 cdna clone
PRDX5 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
PRDX5: Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling. Belongs to the peroxiredoxin 2 family. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: EC 1.11.1.15; Oxidoreductase
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: cytoplasm; cytoplasmic vesicle; cytosol; extracellular space; intracellular membrane-bound organelle; mitochondrial matrix; mitochondrion; nucleus; perinuclear region of cytoplasm; peroxisome
Molecular Function: caspase inhibitor activity; peroxidase activity; protein dimerization activity; receptor binding; thioredoxin peroxidase activity
Biological Process: inflammatory response; negative regulation of apoptosis; negative regulation of transcription from RNA polymerase III promoter; response to oxidative stress; response to reactive oxygen species
Research Articles on PRDX5
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Product Notes
The PRDX5 prdx5 (Catalog #AAA1271357) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggactag ctggcgtgtg cgccctgaga cgctcagcgg gctatatact cgtcggtggg gccggcggtc agtctgcggc agcggcagca agacggtgca gtgaaggaga gtgggcgtct ggcggggtcc gcagtttcag cagagccgct gcagccatgg ccccaatcaa ggtgggagat gccatcccag cagtggaggt gtttgaaggg gagccaggga acaaggtgaa cctggcagag ctgttcaagg gcaagaaggg tgtgctgttt ggagttcctg gggccttcac ccctggatgt tccaagacac acctgccagg gtttgtggag caggctgagg ctctgaaggc caagggagtc caggtggtgg cctgtctgag tgttaatgat gcctttgtga ctggcgagtg gggccgagcc cacaaggcgg aaggcaaggt tcggctcctg gctgatccca ctggggcctt tgggaaggag acagacttat tactagatga ttcgctggtg tccatctttg ggaatcgacg tctcaagagg ttctccatgg tggtacagga tggcatagtg aaggccctga atgtggaacc agatggcaca ggcctcacct gcagcctggc acccaatatc atctcacagc tctga. It is sometimes possible for the material contained within the vial of "PRDX5, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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