PPP1R14D cdna clone
PPP1R14D cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Protein phosphatase-1 (PP1; see MIM 176875) is a major cellular phosphatase that reverses serine/threonine protein phosphorylation. PPP1R14D is a PP1 inhibitor that itself is regulated by phosphorylation (Liu et al., 2004 [PubMed 12974676]).[supplied by OMIM, Feb 2010]
Uniprot Description
GBPI-1: Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. Belongs to the PP1 inhibitor family.
Protein type: Protein phosphatase, regulatory subunit; Inhibitor
Chromosomal Location of Human Ortholog: 15q15.1
Molecular Function: type 1 serine/threonine specific protein phosphatase inhibitor activity
Biological Process: negative regulation of catalytic activity; regulation of protein amino acid dephosphorylation
Research Articles on PPP1R14D
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Product Notes
The PPP1R14D ppp1r14d (Catalog #AAA1278148) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCTGTCTT CAAGCCCTGC TTCCTGCACA TCTCCCAGCC CAGATGGGGA GAACCCATGT AAGAAGGTCC ACTGGGCTTC TGGGAGGAGA AGGACATCAT CCACAGACTC AGAGTCCAAG TCCCACCCGG ACTCCTCCAA GATACCCAGG TCCCGGAGAC CCAGCCGCCT GACAGTGAAG TATGACCGGG GCCAGCTCCA GCGCTGGCTG GAGATGGAGC AATGGGTGGA TGCTCAAGTT CAGGAGCTCT TCCAGGATCA AGCAACCCCT TCTGAGCCTG AGATTGACCT GGAAGCTCTC ATGGATCTAT CCACAGAGGA GCAGAAGACT CAGCTGGAGG CCATTCTTGG GAACTGCCCC CGCCCCACAG AGGCTTTTAT CTCTGAGCTG CTCAGTCAAC TCAAGAAACT CCGGAGACTC AGCCGGCCTC AGAAATAA. It is sometimes possible for the material contained within the vial of "PPP1R14D, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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