PARVB cdna clone
PARVB cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Uniprot Description
PARVB: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Belongs to the parvin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Actin-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 22q13.2-q13.33
Cellular Component: cytosol; focal adhesion; lamellipodium
Molecular Function: protein binding
Biological Process: actin cytoskeleton reorganization; cell projection biogenesis; lamellipodium biogenesis
Research Articles on PARVB
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Product Notes
The PARVB parvb (Catalog #AAA1275736) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaagaagg acgagtcgtt cctgggcaag ctgggcggca ccctggccag gaagcggagg gcgcgcgagg tgagtgacct gcaggaagaa ggcaagaatg ccatcaactc accgatgtcc cccgccctgg cggatgttca ccctgaagac acccagctcg aggagaacga ggagcgcacg atgattgacc ccacttccaa ggaagacccc aagttcaagg aactggtcaa ggtcctcctc gactggatta atgacgtgct ggtggaggag aggatcattg tgaagcagct ggaggaagac ctgtatgacg gccaggtgct gcagaagctc ttggaaaaac tggcagggtg caagctgaat gtggctgagg tgacacagtc cgaaataggg cagaaacaga agctgcagac ggtgctggaa gcagtacatg acctgctgcg gccccgaggc tgggcgctcc ggtggagcgt ggactcaatt cacgggaaga acctggtggc catcctccac ctgctggtct ctctggccat gcacttcagg gcccccatcc gccttcctga gcatgtaacg gtgcaggtgg tggtcgtgcg gaaacgggaa ggcctgctgc attccagcca catctcggag gagctgacca caactacaga gatgatgatg ggccggttcg agcgggatgc cttcgacacg ctgttcgacc acgccccgga taagctcagc gtggtgaaga agtctctcat cacttttgtg aacaagcacc tgaacaagct gaatttggag gtgacggaac tggagaccca gtttgcagat ggcgtgtacc tggttctgct catgggcctt ctggaagact actttgttcc tctccaccac ttctacctga ctccggaaag cttcgatcag aaggtccaca atgtgtcctt tgcctttgag ctgatgctgg acggaggcct caagaaaccc aaggctcgtc ctgaagacgt ggttaacttg gacctcaaat ccaccctgag ggttctttac aacctgttca ccaagtacaa gaacgtggag tga. It is sometimes possible for the material contained within the vial of "PARVB, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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