PAN2 cdna clone
PAN2 cDNA Clone
Gene Names
PAN2; USP52
Synonyms
PAN2; PAN2 cDNA Clone; PAN2 cdna clone
Sequence
atgaactttgagggtctggaccctggactggcagaatatgccccagccatgcattctgccctggaccctgtcttggatgcccacctgaacccaaatctgctacagaatgtggagctggacccagagggagtggccttggaggctcttcccgtccaggaatcagtgcacataatggaaggtgtctactctgaattgcacagcgtggtggctgaagtgggtgtacctgtttccgtctcccactttgacttgcacgaggagatgctgtgggtggggagccacgggggccatgccacttcattttttggcccagccttggagcgctactcatcctttcaagtcaatggcagtgatgatattcggcagatccagagcctggagaatggtatcctttttctcaccaagaacaacctcaagtatatggcccgtgggggcctcattatatttgattacctgctggatgagaatgaggatatgcacagtctcctactgactgacagcagcactctactcgttggtgggctgcagaatcacatactagagattgatcttaacactgtccaggagactcagaagtatgcagtagagacgcctggagtcaccatcatgagacagacaaatcgcttcttcttctgcggccacacgtctggcaaggtttccctgagagacctccgtacttttaaggtggaacatgagtttgatgccttctcaggaagtctgtcagactttgatgtgcatggcaacctgctagctgcctgtggcttctccagccgcctcactggcctggcctgcgaccgtttcctcaaggtgtatgatttgcgcatgatgcgtgccatcacaccacttcaagtacatgtggatcctgccttcttgcgcttcattcctacatatacttctcgtcttgctatcatctctcagtcagggcagtgccaattctgtgaacccacaggcctggccaacccagccgatatctttcatgtgaatcctgtggggcctctgctaatgacatttgatgtgtcagccagcaagcaggctctggcctttggggattctgagggctgtgtgcacctctggactgattccccggagccttccttcaacccctactcccgtgagactgagtttgctttgccgtgtctcgtggactcactgcctcctctggactggagccaggacctgctgcctctttccctcatccctgtcccactcaccactgacacacttctctctgattggcctgctgccaactctgctccagctcccaggcgagcaccacccgtggatgcagagattctgcgcaccatgaagaaggtgggcttcattggctatgcgcccaatccccgcaccaggctgcgcaatcagataccctacagactcaaggagtcagacagtgaatttgacagcttcagccaggtcactgagtcaccagtaggacgagaagaggaaccacatctccacatggtttctaagaaataccgcaaggtgaccatcaaatattccaagctagggctggaggactttgacttcaaacactacaataagaccttgtttgctggattagagccccacattcccaacgcctactgtaactgcatgatccaggtgctctatttcctggagcctgtacgctgtctaattcaaaaccacctttgccagaaggagttctgtctggcatgtgagctgggcttcctgtttcacatgttggacctctctcgtggtgacccttgccagggcaataattttcttcgggcattccgtactattcctgaggcctcagccctcggtctaatcctggctgactcagatgaggcctcaggcaagggcaatctggccaggctcattcagaggtggaatcgcttcattctcactcaactgcatcaagatatgcaggagctggaaataccacaggcttatcgaggtgctggaggcagcagcttttgctcatcgggggactctgttattgggcagctcttcagctgtgagatggagaactgcagcctctgccgctgtggcagtgagaccgtgcgagcctcatccactctgcttttcacactctcctaccctgatgataaaactgggaagaactatgactttgctcaggtgctgaagcgaagcatctgcctggaccagaatacacaggcctggtgtgacacctgtgaaaagtaccagcccacgattcagacccgcaacatccgccatctgccagatattcttgtcatcaattgtgaggtgaacagctcaaaagaggctgatttctggagaatgcaggctgaggttgccttcaagatggcagtaaagaaacacggtggggaaatctccaagaacaaggaatttgctttggctgattggaaggaactagggagtccagagggtgtgctggtgtgtccctccattgaggagttgaagaacgtctggcttcctttctccattcgcatgaagatgaccaaaaacaaagggctggatgtttgcaattggactgatggggatgagatgcagtggggcccagccagggcagaggaggagcatggtgtctatgtgtatgacctgatggctactgtggtacacatcctggactcacgcacagggggcagcctggtggctcacatcaaagttggagagacctaccaccagcgcaaggagggcgttactcaccagcagtggtatctgttcaatgactttcttattgaacctattgataagcatgaagctgtgcagtttgacatgaattggaaagtacctgcaatcctttattatgtcaaacggaatctcaattccagatacaacctgaacatcaagaaccctattgaggcaagtgtcttgctggctgaagcctcgctggcacggaagcagcggaaaacacatactacctttattccactgatgctgaatgagatgccacagattggggacctggtgggtctggatgctgagtttgtcacccttaatgaggaggaagcagagttacgcagtgatggtaccaagtctaccattaaaccaagccagatgtcagtagccaggattacctgtgttcggggccagggacccaatgagggtatccccttcattgatgactacatctctacccaggagcaggtggtggattacttgactcaatactcgggtataaagcctggtgacctcgatgccaaaatttcctccaagcacctaacaactctcaagtctacctacttaaagcttcgttttctcattgacattggagtcaagtttgtgggtcatggcctgcagaaggacttccgggtcatcaacctgatggtgcccaaggaccaagtccttgacactgtctacctgttccatatgccccgaaaacgaatgatttccctgcgattccttgcttggtactttctggacctgaagattcaaggggaaacccatgacagtattgaggatgcccgcacagcccttcagctgtaccgaaagtatctggagctaagcaaaaatggcactgagcctgagtctttccacaaggtgctcaagggtctttatgagaagggcagaaagatggactggaaggtgcctgagcctgagggccaaacaagtcccaagaatgcagctgtcttctcctcagtgctggcgctctga
Sequence Length
3597
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
135,281 Da
NCBI Official Full Name
Homo sapiens PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
PAN2 poly(A) specific ribonuclease subunit
NCBI Official Symbol
PAN2
NCBI Official Synonym Symbols
USP52
NCBI Protein Information
PAB-dependent poly(A)-specific ribonuclease subunit PAN2
UniProt Protein Name
PAB-dependent poly(A)-specific ribonuclease subunit PAN2
Protein Family
UniProt Gene Name
PAN2
UniProt Synonym Gene Names
hPan2
UniProt Entry Name
PAN2_HUMAN
NCBI Description
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
USP52: Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein. Belongs to the peptidase C19 family. PAN2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.13.4; Ribonuclease; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: cytosol
Molecular Function: 3'-5'-exoribonuclease activity; poly(A)-specific ribonuclease activity; protein binding
Biological Process: poly(A) tail shortening
Research Articles on PAN2
Similar Products
Product Notes
The PAN2 pan2 (Catalog #AAA1272582) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaactttg agggtctgga ccctggactg gcagaatatg ccccagccat gcattctgcc ctggaccctg tcttggatgc ccacctgaac ccaaatctgc tacagaatgt ggagctggac ccagagggag tggccttgga ggctcttccc gtccaggaat cagtgcacat aatggaaggt gtctactctg aattgcacag cgtggtggct gaagtgggtg tacctgtttc cgtctcccac tttgacttgc acgaggagat gctgtgggtg gggagccacg ggggccatgc cacttcattt tttggcccag ccttggagcg ctactcatcc tttcaagtca atggcagtga tgatattcgg cagatccaga gcctggagaa tggtatcctt tttctcacca agaacaacct caagtatatg gcccgtgggg gcctcattat atttgattac ctgctggatg agaatgagga tatgcacagt ctcctactga ctgacagcag cactctactc gttggtgggc tgcagaatca catactagag attgatctta acactgtcca ggagactcag aagtatgcag tagagacgcc tggagtcacc atcatgagac agacaaatcg cttcttcttc tgcggccaca cgtctggcaa ggtttccctg agagacctcc gtacttttaa ggtggaacat gagtttgatg ccttctcagg aagtctgtca gactttgatg tgcatggcaa cctgctagct gcctgtggct tctccagccg cctcactggc ctggcctgcg accgtttcct caaggtgtat gatttgcgca tgatgcgtgc catcacacca cttcaagtac atgtggatcc tgccttcttg cgcttcattc ctacatatac ttctcgtctt gctatcatct ctcagtcagg gcagtgccaa ttctgtgaac ccacaggcct ggccaaccca gccgatatct ttcatgtgaa tcctgtgggg cctctgctaa tgacatttga tgtgtcagcc agcaagcagg ctctggcctt tggggattct gagggctgtg tgcacctctg gactgattcc ccggagcctt ccttcaaccc ctactcccgt gagactgagt ttgctttgcc gtgtctcgtg gactcactgc ctcctctgga ctggagccag gacctgctgc ctctttccct catccctgtc ccactcacca ctgacacact tctctctgat tggcctgctg ccaactctgc tccagctccc aggcgagcac cacccgtgga tgcagagatt ctgcgcacca tgaagaaggt gggcttcatt ggctatgcgc ccaatccccg caccaggctg cgcaatcaga taccctacag actcaaggag tcagacagtg aatttgacag cttcagccag gtcactgagt caccagtagg acgagaagag gaaccacatc tccacatggt ttctaagaaa taccgcaagg tgaccatcaa atattccaag ctagggctgg aggactttga cttcaaacac tacaataaga ccttgtttgc tggattagag ccccacattc ccaacgccta ctgtaactgc atgatccagg tgctctattt cctggagcct gtacgctgtc taattcaaaa ccacctttgc cagaaggagt tctgtctggc atgtgagctg ggcttcctgt ttcacatgtt ggacctctct cgtggtgacc cttgccaggg caataatttt cttcgggcat tccgtactat tcctgaggcc tcagccctcg gtctaatcct ggctgactca gatgaggcct caggcaaggg caatctggcc aggctcattc agaggtggaa tcgcttcatt ctcactcaac tgcatcaaga tatgcaggag ctggaaatac cacaggctta tcgaggtgct ggaggcagca gcttttgctc atcgggggac tctgttattg ggcagctctt cagctgtgag atggagaact gcagcctctg ccgctgtggc agtgagaccg tgcgagcctc atccactctg cttttcacac tctcctaccc tgatgataaa actgggaaga actatgactt tgctcaggtg ctgaagcgaa gcatctgcct ggaccagaat acacaggcct ggtgtgacac ctgtgaaaag taccagccca cgattcagac ccgcaacatc cgccatctgc cagatattct tgtcatcaat tgtgaggtga acagctcaaa agaggctgat ttctggagaa tgcaggctga ggttgccttc aagatggcag taaagaaaca cggtggggaa atctccaaga acaaggaatt tgctttggct gattggaagg aactagggag tccagagggt gtgctggtgt gtccctccat tgaggagttg aagaacgtct ggcttccttt ctccattcgc atgaagatga ccaaaaacaa agggctggat gtttgcaatt ggactgatgg ggatgagatg cagtggggcc cagccagggc agaggaggag catggtgtct atgtgtatga cctgatggct actgtggtac acatcctgga ctcacgcaca gggggcagcc tggtggctca catcaaagtt ggagagacct accaccagcg caaggagggc gttactcacc agcagtggta tctgttcaat gactttctta ttgaacctat tgataagcat gaagctgtgc agtttgacat gaattggaaa gtacctgcaa tcctttatta tgtcaaacgg aatctcaatt ccagatacaa cctgaacatc aagaacccta ttgaggcaag tgtcttgctg gctgaagcct cgctggcacg gaagcagcgg aaaacacata ctacctttat tccactgatg ctgaatgaga tgccacagat tggggacctg gtgggtctgg atgctgagtt tgtcaccctt aatgaggagg aagcagagtt acgcagtgat ggtaccaagt ctaccattaa accaagccag atgtcagtag ccaggattac ctgtgttcgg ggccagggac ccaatgaggg tatccccttc attgatgact acatctctac ccaggagcag gtggtggatt acttgactca atactcgggt ataaagcctg gtgacctcga tgccaaaatt tcctccaagc acctaacaac tctcaagtct acctacttaa agcttcgttt tctcattgac attggagtca agtttgtggg tcatggcctg cagaaggact tccgggtcat caacctgatg gtgcccaagg accaagtcct tgacactgtc tacctgttcc atatgccccg aaaacgaatg atttccctgc gattccttgc ttggtacttt ctggacctga agattcaagg ggaaacccat gacagtattg aggatgcccg cacagccctt cagctgtacc gaaagtatct ggagctaagc aaaaatggca ctgagcctga gtctttccac aaggtgctca agggtcttta tgagaagggc agaaagatgg actggaaggt gcctgagcct gagggccaaa caagtcccaa gaatgcagct gtcttctcct cagtgctggc gctctga. It is sometimes possible for the material contained within the vial of "PAN2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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