MAP4 cdna clone
MAP4 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Uniprot Description
MAP4: a microtuble-associated protein detected predominately in nonneuronal cells. May play a role in microtubule stabilization as well as promoting microtubule assembly. Four alternatively spliced variants have been described.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3p21
Cellular Component: axoneme; cytoplasm; microtubule associated complex; microtubule cytoskeleton; neuron projection; plasma membrane
Molecular Function: microtubule binding; protein binding; structural molecule activity
Biological Process: cell division; establishment of spindle orientation; microtubule sliding; mitotic spindle organization and biogenesis; neurite development
Research Articles on MAP4
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Product Notes
The MAP4 map4 (Catalog #AAA1267212) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctgacc tcagtcttgc agatgcatta acagaaccat ctccagacat tgagggagag ataaagcggg acttcattgc cacactagag gcagaggcct ttgatgatgt tgtgggagaa actgttggaa aaacagacta tattcctctc ctggatgttg atgagaaaac cgggaactca gagtcaaaga agaaaccgtg ctcagaaact agccagattg aagatactcc atcttctaaa ccaacactcc tagccaatgg tggtcatgga gtagaaggga gcgatactac agggtctcca actgaattcc ttgaagagaa aatggcctac caggaatacc caaatagcca gaactggcca gaagatacca acttttgttt ccaacctgag caagtggtcg atcctatcca gactgatccc tttaagatgt accatgatga tgacctggca gatttggtct ttccctccag tgcgacagct gatacttcaa tatttgcagg acaaaatgat cccttgaaag acagttacgg tatgtctccc tgcaacacag ctgttgtacc tcaggggtgg tctgtggaag ccttaaactc tccacactca gagtcctttg tttccccaga ggctgttgca gaacctcctc agccaacggc agttccctta gagctagcca aggagataga aatggcatca gaagagaggc caccagcaca agcattggaa ataatgatgg gactgaagac tactgacatg gcaccatcta aagaaacaga gatggccctc gccaaggaca tggcactagc tacaaaaacc gaggtggcat tggctaaaga tatggaatca cccaccaaat tagatgtgac actggccaag gacatgcagc catccatgga atcagatatg gccctagtca aggacatgga actacccaca gaaaaagaag tggccctggt taaggatgtc agatggccca cagaaacaga tgtatcttca gccaagaatg tggtactgcc cacagaaaca gaggtagccc cagccaagga tgtgacactg ttgaaagaaa cagagagggc atctcctata aaaatggact tagccccttc caaggacatg ggaccaccca aagaaaacaa gaaagaaaca gagagggcat ctcctataaa aatggacttg gctccttcca aggacatggg accacccaaa gaaaacaaga tagtcccagc caaggatttg gtattactct cagaaataga ggtggcacag gctaatgaca ttatatcatc cacagaaata tcctctgctg agaaggtggc tttgtcctca gaaacagagg tagccctggc cagggacatg acactgcccc cggaaaccaa cgtgatcttg accaaggata aagcactacc tttagaagca gaggtggccc cagtcaagga catggctcaa ctcccagaaa cagaaatagc cccggccaag gatgtggctc cgtccacagt aaaagaagtg ggcttgttga aggacatgtc tccactatca gaaacagaaa tggctctggg caaggatgtg actccacctc cagaaacaga agtagttctc atcaagaacg tatgtctgcc tccagaaatg gaggtggccc tgactgagga tcaggtccca gccctcaaaa cagaagctcc caccaccatt ggtgggttga ataaaaaacc catgagcctt gcttcaggct tagtgccagc tgccccaccc aaacgccctg ccgtcgcctc tgccaggcct tccatcttac cttcaaaaga cgtgaagcca aagcccattg cagatgcaaa ggctcctgag aagcgggcct caccatccaa gccagcttct gccccagcct ccagatctgg gtccaagagc actcagactg ttgcaaaaac cacaacagct gctgctgttg cctcaactgg cccaagcagt aggagcccct ccacgctcct gcccaagaag cccactgcca ttaagactga gggaaaacct gcagaagtca agaagatgac tgcaaagtct gtaccagctg acttgagtcg cccaaagagc acctccacca gttccatgaa gaaaaccacc actctcagtg ggacagcccc cgctgcaggg gtggttccca gccgagtcaa ggccacaccc atgccctccc ggccctccac aactcctttc atagacaaga agcccacctc ggccaaaccc agctccacca ccccccggct cagccgcctg gccaccaata cttctgctcc tgatctgaag aatgtccgct ccaaggttgg ctccacggaa aacatcaagc atcagcctgg aggaggccgg gccaaagtag agaaaaaaac agaggcagct gctacaaccc gaaagcctga atctaatgca gtcactaaaa cagccggccc aattgcaagt gcacagaaac aacctgcggg gaaagtccag atagtctcca aaaaagtgag ctacagccat attcagtcca agtgtggttc caaggacaat attaagcatg tccctggagg tggtaatgtt cagattcaga acaagaaagt ggacatctct aaggtctcct ccaagtgtgg gtctaaggct aacatcaagc acaagcctgg tggaggagat gtcaagattg aaagtcagaa gttgaacttc aaggagaagg cccaggccaa ggtgggatcc ctcgataatg tgggccacct acctgcagga ggtgctgtga agactgaggg cggtggcagc gaggctcctc tgtgtccggg tccccctgct ggggaggagc cggccatctc tgaggcagcg cctgaagctg gcgcccccac ttcagccagt ggcctcaatg gccaccccac cctgtcaggg ggtggtgacc aaagggaggc ccagaccttg gacagccaga tccaggagac aagcatctaa. It is sometimes possible for the material contained within the vial of "MAP4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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