ITGB6 cdna clone
ITGB6 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
ITGB6: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Belongs to the integrin beta chain family.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 2q24.2
Cellular Component: plasma membrane; receptor complex
Biological Process: cell adhesion; extracellular matrix organization and biogenesis
Disease: Amelogenesis Imperfecta, Type Ih
Research Articles on ITGB6
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Product Notes
The ITGB6 itgb6 (Catalog #AAA1278890) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGGATTG AACTGCTTTG CCTGTTCTTT CTATTTCTAG GAAGGAATGA TCACGTACAA GGTGGCTGTG CCCTGGGAGG TGCAGAAACC TGTGAAGACT GCCTGCTTAT TGGACCTCAG TGTGCCTGGT GTGCTCAGGA GAATTTTACT CATCCATCTG GAGTTGGCGA AAGGTGTGAT ACCCCAGCAA ACCTTTTAGC TAAAGGATGT CAATTAAACT TCATCGAAAA CCCTGTCTCC CAAGTAGAAA TACTTAAAAA TAAGCCTCTC AGTGTAGGCA GACAGAAAAA TAGTTCTGAC ATTGTTCAGA TTGCGCCTCA AAGCTTGATC CTTAAGTTGA GACCAGGTGG TGCGCAGACT CTGCAGGTGC ATGTCCGCCA GACTGAGGAC TACCCGGTGG ATTTGTATTA CCTCATGGAC CTCTCCGCCT CCATGGATGA CGACCTCAAC ACAATAAAGG AGCTGGGCTC CCGGCTTTCC AAAGAGATGT CTAAATTAAC CAGCAACTTT AGACTGGGCT TCGGATCTTT TGTGGAAAAA CCTGTATCCC CTTTTGTGAA AACAACACCA GAAGAAATTG CCAACCCTTG CAGTAGTATT CCATACTTCT GTTTACCTAC ATTTGGATTC AAGCACATTT TGCCATTGAC AAATGATGCT GAAAGATTCA ATGAAATTGT GAAGAATCAG AAAATTTCTG CTAATATTGA CACACCCGAA GGTGGATTTG ATGCAATTAT GCAAGCTGCT GTGTGTAAGG AAAAAATTGG CTGGCGGAAT GACTCCCTCC ACCTCCTGGT CTTTGTGAGT GATGCTGATT CTCATTTTGG AATGGACAGC AAACTAGCAG GCATCGTCAT TCCTAATGAC GGGCTCTGTC ACTTGGACAG CAAGAATGAA TACTCCATGT CAACTGTCTT GGAATATCCA ACAATTGGAC AACTCATTGA TAAACTGGTA CAAAACAACG TGTTATTGAT CTTCGCTGTA ACCCAAGAAC AAGTTCATTT ATATGAGAAT TACGCAAAAC TTATTCCTGG AGCTACAGTA GGTCTACTTC AGAAGGACTC CGGAAACATT CTCCAGCTGA TCATCTCAGC TTATGAAGAA CTGCGGTCTG AGGTGGAACT GGAAGTATTA GGAGACACTG AAGGACTCAA CTTGTCATTT ACAGCCATCT GTAACAACGG TACCCTCTTC CAACACCAAA AGAAATGCTC TCACATGAAA GTGGGAGACA CAGCTTCCTT CAGCGTGACT GTGAATATCC CACACTGCGA GAGAAGAAGC AGGCACATTA TCATAAAGCC TGTGGGGCTG GGGGATGCCC TGGAATTACT TGTCAGCCCA GAATGCAACT GCGACTGTCA GAAAGAAGTG GAAGTGAACA GCTCCAAATG TCACCACGGG AACGGCTCTT TCCAGTGTGG GGTGTGTGCC TGCCACCCTG GCCACATGGG GCCTCGCTGT GAGTGTGGCG AGGACATGCT GAGCACAGAT TCCTGCAAGG AGGCCCCAGA TCATCCCTCC TGCAGCGGAA GGGGTGACTG CTACTGTGGG CAGTGTATCT GCCACTTGTC TCCCTATGGA AACATTTATG GGCCTTATTG CCAGTGTGAC AATTTCTCCT GCGTGAGACA CAAAGGGCTG CTCTGCGGAG GTAACGGCGA CTGTGACTGT GGTGAATGTG TGTGCAGGAG CGGCTGGACT GGCGAGTACT GCAACTGCAC CACCAGCACG GACTCCTGCG TCTCTGAAGA TGGAGTGCTC TGCAGCGGGC GCGGGGACTG TGTTTGTGGC AAGTGTGTTT GCACAAACCC TGGAGCCTCA GGACCAACCT GTGAACGATG TCCTACCTGT GGTGACCCCT GTAACTCTAA ACGGAGCTGC ATTGAGTGCC ACCTGTCAGC AGCTGGCCAA GCCCGAGAAG AATGTGTGGA CAAGTGCAAA CTAGCTGGTG CGACCATCAG TGAAGAAGAA GATTTCTCAA AGGATGGTTC TGTTTCCTGC TCTCTGCAAG GAGAAAATGA ATGTCTTATT ACATTCCTAA TAACTACAGA TAACGAGGGG AAAACCATCA TTCACAGCAT CAATGAAAAA GATTGTCCGA AGCCTCCAAA CATTCCCATG ATCATGTTAG GGGTTTCCCT GGCTATTCTT CTCATCGGGG TTGTCCTACT GTGCATCTGG AAGCTACTGG TGTCATTTCA TGATCGTAAA GAAGTTGCCA AATTTGAAGC AGAACGATCA AAAGCCAAGT GGCAAACGGG AACCAATCCA CTCTACAGAG GATCCACAAG TACTTTTAAA AATGTAACTT ATAAACACAG GGAAAAACAA AAGGTAGACC TTTCCACAGA TTGCTAG. It is sometimes possible for the material contained within the vial of "ITGB6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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