IFNB1 cdna clone
IFNB1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
Uniprot Description
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 9p21
Cellular Component: extracellular region; extracellular space
Molecular Function: chloramphenicol O-acetyltransferase activity; cytokine activity; interferon-alpha/beta receptor binding
Biological Process: B cell activation during immune response; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor linked signal transduction; defense response to virus; humoral immune response; natural killer cell activation during immune response; negative regulation of T cell differentiation; negative regulation of viral genome replication; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription from RNA polymerase II promoter; response to exogenous dsRNA; T cell activation during immune response
Research Articles on IFNB1
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Product Notes
The IFNB1 ifnb1 (Catalog #AAA1270047) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGACCAACA AGTGTCTCCT CCAAATTGCT CTCCTGTTGT GCTTCTCCAC TACAGCTCTT TCCATGAGCT ACAACTTGCT TGGATTCCTA CAAAGAAGCA GCAATTTTCA GTGTCAGAAG CTCCTGTGGC AATTGAATGG GAGGCTTGAA TACTGCCTCA AGGACAGGAT GAACTTTGAC ATCCCTGAGG AGATTAAGCA GCTGCAGCAG TTCCAGAAGG AGGACGCCGC ATTGACCATC TATGAGATGC TCCAGAACAT CTTTGCTATT TTCAGACAAG ATTCATCTAG CACTGGCTGG AATGAGACTA TTGTTGAGAA CCTCCTGGCT AATGTCTATC ATCAGATAAA CCATCTGAAG ACAGTCCTGG AAGAAAAACT GGAGAAAGAA GATTTCACCA GGGGAAAACT CATGAGCAGT CTGCACCTGA AAAGATATTA TGGGAGGATT CTGCATTACC TGAAGGCCAA GGAGTACAGT CACTGTGCCT GGACCATAGT CAGAGTGGAA ATCCTAAGGA ACTTTTACTT CATTAACAGA CTTACAGGTT ACCTCCGAAA CTGA. It is sometimes possible for the material contained within the vial of "IFNB1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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