HTATIP2 cdna clone
HTATIP2 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
HTATIP2: Oxidoreductase required for tumor suppression. NAPDH- bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Nuclear envelope; Transcription factor; EC 1.1.1.-; Tumor suppressor; Oxidoreductase
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: cytoplasm; membrane; nuclear envelope; nucleoplasm; nucleus
Molecular Function: protein binding; transcription coactivator activity
Biological Process: negative regulation of apoptosis; nuclear import; regulation of angiogenesis; regulation of transcription from RNA polymerase II promoter
Research Articles on HTATIP2
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Product Notes
The HTATIP2 htatip2 (Catalog #AAA1273636) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccgaaa cagaagccct gtcgaagctt cgggaagact tcaggatgca gaataaatcc gtctttattt tgggcgccag cggagaaacc ggcagagtgc tcttaaagga aatcctggag cagggcctgt tttccaaagt cacgctcatt ggccggagga agctcacctt cgacgaggaa gcttataaaa atgtgaatca agaagtggtg gactttgaaa agttggatga ctacgcctct gcctttcaag gtcatgatgt tggattctgt tgcctgggta ccaccagagg gaaagctggg gcggagggat ttgttcgtgt tgaccgagat tatgtgctga agtctgcaga gctggcaaaa gctggagggt gcaaacattt caacttgcta tcctctaaag gagctgataa atcaagcaat tttttatatc tacaagttaa gggagaagta gaagccaagg ttgaagaatt aaaatttgat cgttactctg tatttaggcc tggagttctg ttatgtgata ggcaagaatc tcgcccaggt gaatggctgg ttagaaagtt ctttggctcc ttaccagact cttgggccag ggggcattct gtgcctgtgg tgaccgtggt tagagcaatg ctgaacaatg tggtgagacc aagagacaag cagatggaac tgctggagaa caaggccatc catgacctgg ggaaagcgca tggctctctc aagccatga. It is sometimes possible for the material contained within the vial of "HTATIP2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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