GINS4 cdna clone
GINS4
Gene Names
GINS4; SLD5
Synonyms
GINS4; SLD5; GINS4 cdna clone
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGACCGAAGAAGTGGATTTCCTGGGACAGGACTCTGATGGGGGTAGTGAGGAAGTGGTCCTAACTCCTGCAGAGCTCATTGAAAGATTGGAGCAGGCCTGGATGAATGAAAAGTTTGCCCCTGAGCTGCTGGAGAGCAAGCCTGAGATTGTAGAATGTGTCATGGAACAGCTGGAGCACATGGAAGAAAATCTCAGGAGAGCCAAAAGGGAGGACCTGAAGGTCAGCATCCACCAAATGGAGATGGAGAGGATCCGCTACGTCCTCAGCAGCTACTTGCGGTGTCGCCTCATGAAGATAGAGAAGTTTTTCCCTCATGTCCTTGAGAAGGAAAAAACACGTCCTGAGGGGGAGCCTTCCAGCCTCTCGCCGGAAGAGTTGGCCTTTGCCAGAGAGTTCATGGCGAACACAGAGTCCTATCTGAAAAATGTCGCCTTGAAGCACATGCCCCCTAACTTACAGAAGGTGGACCTCTTTCGGGCAGTTCCCAAACCAGATCTAGATTCTTACGTGTTTCTGAGAGTGAGAGAACGACAAGAAAACATACTGGTAGAACCAGACACAGATGAGCAGAGGGACTACGTGATTGACCTGGAGAAGGGCTCACAGCACTTGATCCGATACAAAACCATTGCACCTCTGGTTGCATCTGGAGCTGTCCAGCTAATTTAA
Translation Sequence: MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI
Translation Sequence: MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI
Sequence Length
223
Species
Human
Chromosome Location
8p11.21
OMIM Reference Number
610611
cDNA Size
672bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted Nde I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Product Categories/Family for GINS4 cdna clone
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
DNA replication complex GINS protein SLD5
NCBI Official Synonym Full Names
GINS complex subunit 4
NCBI Official Symbol
GINS4
NCBI Official Synonym Symbols
SLD5
NCBI Protein Information
DNA replication complex GINS protein SLD5
UniProt Protein Name
DNA replication complex GINS protein SLD5
UniProt Gene Name
GINS4
UniProt Synonym Gene Names
SLD5
UniProt Entry Name
SLD5_HUMAN
NCBI Description
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Uniprot Description
GINS4: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA. Belongs to the GINS4/SLD5 family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: protein binding
Biological Process: mitotic cell cycle; DNA strand elongation during DNA replication; inner cell mass cell proliferation
Research Articles on GINS4
Similar Products
Product Notes
The GINS4 gins4 (Catalog #AAA200810) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGACCGAAG AAGTGGATTT CCTGGGACAG GACTCTGATG GGGGTAGTGA GGAAGTGGTC CTAACTCCTG CAGAGCTCAT TGAAAGATTG GAGCAGGCCT GGATGAATGA AAAGTTTGCC CCTGAGCTGC TGGAGAGCAA GCCTGAGATT GTAGAATGTG TCATGGAACA GCTGGAGCAC ATGGAAGAAA ATCTCAGGAG AGCCAAAAGG GAGGACCTGA AGGTCAGCAT CCACCAAATG GAGATGGAGA GGATCCGCTA CGTCCTCAGC AGCTACTTGC GGTGTCGCCT CATGAAGATA GAGAAGTTTT TCCCTCATGT CCTTGAGAAG GAAAAAACAC GTCCTGAGGG GGAGCCTTCC AGCCTCTCGC CGGAAGAGTT GGCCTTTGCC AGAGAGTTCA TGGCGAACAC AGAGTCCTAT CTGAAAAATG TCGCCTTGAA GCACATGCCC CCTAACTTAC AGAAGGTGGA CCTCTTTCGG GCAGTTCCCA AACCAGATCT AGATTCTTAC GTGTTTCTGA GAGTGAGAGA ACGACAAGAA AACATACTGG TAGAACCAGA CACAGATGAG CAGAGGGACT ACGTGATTGA CCTGGAGAAG GGCTCACAGC ACTTGATCCG ATACAAAACC ATTGCACCTC TGGTTGCATC TGGAGCTGTC CAGCTAATTT AA Translatio n Sequence: MTEEVDFLGQ DSDGGSEEVV LTPAELIERL EQAWMNEKFA PELLESKPEI VECVMEQLEH MEENLRRAKR EDLKVSIHQM EMERIRYVLS SYLRCRLMKI EKFFPHVLEK EKTRPEGEPS SLSPEELAFA REFMANTESY LKNVALKHMP PNLQKVDLFR AVPKPDLDSY VFLRVRERQE NILVEPDTDE QRDYVIDLEK GSQHLIRYKT IAPLVASGAV QLI. It is sometimes possible for the material contained within the vial of "GINS4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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