FMNL1 cdna clone

FMNL1 cDNA Clone

Cat. Num. AAA1266149

• Gene Names: FMNL1; FMNL; FHOD4; KW-13; C17orf1; C17orf1B
• Synonyms: FMNL1; FMNL1 cDNA Clone; FMNL1 cdna clone

• Sequence: ATGGGCAACGCGGCCGGCAGCGCCGAGCAGCCCGCGGGCCCCGCCGCGCCGCCCCCCAAGCAGCACCGCTTTGAAAAGCTGATGGAATATTTCCGGAATGAGGACAGCAACATCGACTTCATGGTGGCCTGCATGCAGTTCATCAACATTGTGGTACATTCAGTGGAGAACATGAACTTCCGTGTCTTCCTGCAATATGAGTTCACCCACTTGGGCCTGGACCTGTACTTGGAGAGGCTTCGGCTCACCGAGAGTGACAAGCTGCAGGTGCAGATCCAGGCGTACCTGGACAATATTTTTGATGTGGGGGCGCTGCTGGAGGACACAGAGACCAAGAACGCTGTGCTGGAGCACATGGAGGAACTGCAGGAGCAAGTGGCGCTGCTGACAGAGCGGCTTCGGGACGCGGAGAACGAATCCATGGCCAAGATTGCAGAACTGGAAAAACAGCTAAGCCAGGCGCGCAAGGAGTTGGAGACCCTGCGGGAGCGCTTCAGCGAATCGACCGCCATGGGCGCCTCCAGGCGTCCCCCAGAGCCTGAGAAAGCGCCTCCCGCTGCCCCGACGCGGCCCTCGGCCCTGGAGCTGAAGGTGGAGGAGCTGGAGGAGAAGGGGTTAATCCGTATTCTGCGGGGGCCGGGGGATGCTGTCTCCATCGAGATCCTCCCCGTCGCTGTGGCAACTCCGAGCGGCGGTGATGCTCCGACTCCGGGGGTGCCGACCGGCTCCCCCAGCCCAGATCTCGCACCTGCAGCAGAGCCGGCTCCCGGAGCAGCGCCACCGCCGCCGCCGCCGCCTCCCGGAGGTCCTCCTGATGCCCTAGGAAGACGCGACTCAGAATTGGGCCCAGGAGTGAAGGCCAAGAAGCCCATCCAGACTAAGTTCCGAATGCCACTCTTGAACTGGGTGGCACTGAAACCCAGCCAGATCACCGGCACTGTCTTCACAGAGCTCAATGATGAGAAGGTGCTGCAGGAGCTAGACATGAGTGATTTTGAGGAACAGTTCAAGACCAAGTCCCAAGGCCCCAGCCTGGACCTCAGCGCTCTCAAGAGTAAGGCAGCCCAGAAGGCCCCCAGCAAGGCGACACTCATTGAGGCCAACCGGGCCAAGAACTTGGCCATCACCCTGCGGAAGGGCAACCTGGGGGCCGAGCGCATCTGCCAAGCCATTGAGGCGTACGACCTGCAGGCTCTGGGCCTGGACTTCCTGGAGCTGCTGATGCGCTTCCTGCCCACAGAGTATGAGCGCAGCCTCATCACCCGCTTTGAGCGGGAGCAGCGGCCAATGGAGGAGCTGTCAGAGGAGGACCGCTTCATGCTATGCTTCAGCCGCATCCCGCGCCTGCCGGAGCGCATGACCACACTCACCTTCCTGGGCAACTTCCCGGACACAGCCCAGCTGCTCATGCCGCAACTGAATGCCATCATTGCAGCCTCAATGTCCATCAAGTCCTCTGACAAACTCCGCCAGATCCTGGAGATTGTCCTGGCCTTTGGCAACTACATGAACAGTAGCAAGCGTGGGGCAGCCTATGGCTTCCGGCTCCAGAGCCTGGATGCGCTGTTGGAGATGAAGTCGACTGATCGCAAGCAGACGCTGCTGCACTACCTGGTGAAGGTCATTGCTGAGAAGTACCCGCAACTCACAGGCTTCCACAGCGACCTGCACTTCCTGGACAAGGCGGGCTCAGTGTCCCTGGACAGTGTCCTGGCGGACGTGCGCTCCCTGCAGCGAGGCCTAGAGTTGACACAGAGAGAGTTTGTGCGGCAGGATGACTGCATGGTGCTCAAGGAGTTCCTGAGGGCCAACTCGCCCACCATGGACAAGCTGCTGGCAGACAGCAAGACGGCTCAGGCTGTGCCCACAGGAGGCCTTTGA
• Sequence Length: 1881

• Vector: Please Inquire

NCBI and Uniprot Product Information

• NCBI GI #: 84105550
• NCBI GeneID: 752
• Molecular Weight: 128,335 Da
• NCBI Official Full Name: Homo sapiens formin-like 1, mRNA
• NCBI Official Synonym Full Names: formin like 1
• NCBI Official Symbol: FMNL1
• NCBI Official Synonym Symbols: FMNL; FHOD4; KW-13; C17orf1; C17orf1B
• NCBI Protein Information: formin-like protein 1
• UniProt Protein Name: Formin-like protein 1
• UniProt Gene Name: FMNL1
• UniProt Synonym Gene Names: C17orf1; C17orf1B; FMNL; FRL1
• UniProt Entry Name: FMNL1_HUMAN

NCBI Description

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

FMNL1: May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cytosol; membrane; phagocytic vesicle; plasma membrane

Molecular Function: actin filament binding; GTPase activating protein binding; protein binding; Rac GTPase binding

Biological Process: actin filament severing; cortical actin cytoskeleton organization and biogenesis; regulation of cell shape