FDXR cdna clone
FDXR cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot Description
FDXR: Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Belongs to the ferredoxin--NADP reductase type 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.18.1.6; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: ferredoxin-NADP+ reductase activity; NADPH-adrenodoxin reductase activity; protein binding
Biological Process: C21-steroid hormone biosynthetic process; generation of precursor metabolites and energy; steroid biosynthetic process; sterol metabolic process
Research Articles on FDXR
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Product Notes
The FDXR fdxr (Catalog #AAA1274814) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcttcgc gctgctggcg ctggtggggc tggtcggcgt ggcctcggac ccggctgcct cccgccggga gcaccccgag cttctgccac catttctcca cacaggagaa gaccccccag atctgtgtgg tgggcagtgg cccagctggc ttctacacgg cccaacacct gctaaagcac ccccaggccc acgtggacat ctacgagaaa cagcctgtgc cctttggcct ggtgcgcttt ggtgtggcgc ctgatcaccc cgaggtgaag aatgtcatca acacatttac ccagacggcc cattctggcc gctgtgcctt ctggggcaac gtggaggtgg gcagggacgt gacggtgccg gagctgcggg aggcctacca cgctgtggtg ctgagctacg gggcagagga ccatcgggcc ctggaaattc ctggtgagga gctgccaggt gtgtgctccg cccgggcctt cgtgggctgg tacaacgggc ttcctgagaa ccaggagctg gagccagacc tgagctgtga cacagccgtg attctggggc aggggaacgt ggctctggac gtggcccgca tcctactgac cccacctgag cacctggaga gaacggacat cacgaaggca gccctgggtg tactgaggca gagtcgagtg aagacagtgt ggctagtggg ccggcgtgga cccctgcaag tggccttcac cattaaggag cttcgggaga tgattcagtt accgggagcc cggcccattt tggatcctgt ggatttcttg ggtctccagg acaagatcaa ggaggtcccc cgcccgagga agcggctgac ggaactgctg cttcgaacgg ccacagagaa gccagggccg gcggaagctg cccgccaggc atcggcctcc cgtgcctggg gcctccgctt tttccgaagc ccccagcagg tgctgccctc accagatggg cggcgggcag caggtgtccg cctagcagtc actagactgg agggtgtcga tgaggccacc cgtgcagtgc ccacgggaga catggaagac ctcccttgtg ggctggtgct cagcagcatt gggtataaga gccgccctgt cgacccaagc gtgccctttg actccaagct tggggtcatc cccaatgtgg agggccgggt tatggatgtg ccaggcctct actgcagcgg ctgggtgaag agaggaccta caggtgtcat agccacaacc atgactgaca gcttcctcac cggccagatg ctgctgcagg acctgaaggc tgggttgctc ccctctggcc ccaggcctgg ctacgcagcc atccaggccc tgctcagcag ccgaggggtc cggccagtct ctttctcaga ctgggagaag ctggatgccg aggaggtggc ccggggccag ggcacgggga agcccaggga gaagctggtg gatcctcagg agatgctgcg cctcctgggc cactga. It is sometimes possible for the material contained within the vial of "FDXR, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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