FBXW10 cdna clone
FBXW10 cDNA Clone
Gene Names
FBXW10; HREP; Fbw10; SM25H2; SM2SH2
Synonyms
FBXW10; FBXW10 cDNA Clone; FBXW10 cdna clone
Sequence
atggaaaacctggaatcaaggctcaagaatgccccctattttcgttgtgagaagggaaccgattccatccctctatgccggaagtgtgagacgtgtgtcttagcctggaagatcttctctaccaaagagtggttctgcaggatcaatgacatatcacagaggaggtttctagttggcattctgaagcagttaaatagcttatatttgttacactatttccaaaatatccttcagaccacacagggaaaggatttcatctataacaggtcccggatcaacctcagcaagaaagaggggaaagttgtgaagtcctccttgaaccaaatgttggataaaacagtagaacagaagatgaaagagatcttgtactggtttgcgaacagcacccagtggaccaaggcgaattatactctcttactgctgcagatgtgcaaccccaaattactgctcactgctgccaatgtgatcagagtcctgtttctgagagaggagaacaatatctcagggctcaatcaagacatcacagatgtgtgtttttcccctgagaaagaccacagctccaagtctgcgacctcacaagtctattggacagccaaaactcagcacacatcccttcctttgtccaaagccccagaaaatgaacacttgcttggggcagcatctaaccctgaggaaccatggaggaattcactccggtgtatatccgaaatgaataggctgttttctggaaaaggagacataaccaagccagggtacgatccctgcaatctattggttgacctggatgacatcagagacctgtcttctgggttcagcaaatacctagacttcatccgttacctgcccatccacctctccaagtacattctaagtatgctggggtgtatgaggggatttcccagacacctcccatcttggcccagttctggggtttctgggtccatctttttttttccaggaatgctggatagacacaccctgaacaagtgcgcctctgtgagccagcactgggccgccatggctcaacaggtcaagatggacttgtcagcgcacggcttcattcagaaccagattaccttcttgcaggggtcctacacaagaggaattgatcctaattatgccaataaggtttctatcccagttcctaaaatggtagatgacgggaagagcatgcgtgtgaaacatccgaagtggaagctgagaacgaagaatgagtacaacctgtggactgcataccagaacgaggaaacgcagcaggtcctgatagaggagagaaatgttttctgtgggacctacaatgttcgcattctctctgacacgtgggatcaaaaccgagtcatccactattccgggggagatctgatagctgtgtcatctaatcgaaagatccatcttctggacatcatacaagtgaaagcgatacccgttgaattccgaggccatgctgggagtgtccgggccctcttcctgtgtgaggaggaaaactttctcctaagcgggagctatgacctaagtatcagatactgggatctgaaaagtggggtttgcacacgaatcttcggtggtcaccaggggactatcacttgcatggacttgtgtaagaacaggctcgtatctggaggaagagattgccaggtaaaagtatgggatgtagacacagggaagtgcctgaagacgtttagacacaaagaccccatcttggccaccaggatcaatgatacctacattgtgagcagctgtgagcgagggctggtgaaagtgtggcacattgccatggcccagttggtaaagactctcagtggccatgagggagccgtgaaatgcctgttctttgaccagtggcatctcctctcaggaagtactgatggcctggtcatggcctggagcatggtggggaagtacgagcgctgcctgatggccttcaagcatcccaaggaggtgctcgacgtgtccctcctcttcctccgggtcatcagcgcctgtgcagatggcaagatccgaatttacaatttcctcaacgggaactgtatgaaggtgttaaaagccaatggcagaggtgatcctgtgctgtccttctttattcagggcaacaggatggtggtcaacacagagagcaatgttctcatgttccagtttgagcacataaagtggcagtatgccgtggaaaaaacgaaacaaaagaagaataaggagaaagaggaggaaaaagaagaaaatagtctcatggaaattctctctaagtgtaatattcaggttcacagcccaagagagtctgtatccagtaaacaaactgtgatccaagagctcctaccaggcaaacctcccaagtcccgagtactcctgaagccggccaagttctcttcagatgatgtggagaaagcacaaaaacaaggacaattggaaactcctggaaaactgcccagtcacccaaagaaaaagtcttggaaaatccctatgtcacctgaccaattcctcctgactgttagcgccctgcagcacgcccataattccggggaatttgcctatccctgtaggccccaaacagaaattactgatgtctggggaccttcaatttcatacccaaggaaggtcttgaatttcaaaggaaaatcaatccaacgtgcagttgatcggttgagattgagcaatcctcctatagatgtgaaacgaaccagtattccccttgaaatccagaaactgcagcccaacttgaagatctctttgcacagtcctagagtccagtccaccataccccagcccatgattatccgctccaggttctctggcagcttaaagggtggagaccaagtgaccagttcaattgaaagggctgtgtgcagtacgggtcccctgaccagtatgcaggtcattaaaccaaaccgcatgctagctccacaagtgggcacagccaccctgtctcttaagaaagaacggcctcgcatctatacagcccttgatccttttagagtgaacactgagttcgtgctgttgaccgtgaaggaggagaaggagcaccaggaagccaagatgaaggaatatcaggccagggagtccactggagtggttgatccaggaaaagtcagcaaagctgcatggatcaggaagatcaaaggcctgcctattgataatttcacgaagcaagggaaaacagcggcccctgaacttggacaaaatgtatttatctaa
Sequence Length
3186
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
119,774 Da
NCBI Official Full Name
Homo sapiens F-box and WD repeat domain containing 10, mRNA
NCBI Official Synonym Full Names
F-box and WD repeat domain containing 10
NCBI Official Symbol
FBXW10
NCBI Official Synonym Symbols
HREP; Fbw10; SM25H2; SM2SH2
NCBI Protein Information
F-box/WD repeat-containing protein 10
UniProt Protein Name
F-box/WD repeat-containing protein 10
Protein Family
UniProt Gene Name
FBXW10
UniProt Entry Name
FBW10_HUMAN
NCBI Description
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Uniprot Description
Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
Research Articles on FBXW10
Similar Products
Product Notes
The FBXW10 fbxw10 (Catalog #AAA1267702) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggaaaacc tggaatcaag gctcaagaat gccccctatt ttcgttgtga gaagggaacc gattccatcc ctctatgccg gaagtgtgag acgtgtgtct tagcctggaa gatcttctct accaaagagt ggttctgcag gatcaatgac atatcacaga ggaggtttct agttggcatt ctgaagcagt taaatagctt atatttgtta cactatttcc aaaatatcct tcagaccaca cagggaaagg atttcatcta taacaggtcc cggatcaacc tcagcaagaa agaggggaaa gttgtgaagt cctccttgaa ccaaatgttg gataaaacag tagaacagaa gatgaaagag atcttgtact ggtttgcgaa cagcacccag tggaccaagg cgaattatac tctcttactg ctgcagatgt gcaaccccaa attactgctc actgctgcca atgtgatcag agtcctgttt ctgagagagg agaacaatat ctcagggctc aatcaagaca tcacagatgt gtgtttttcc cctgagaaag accacagctc caagtctgcg acctcacaag tctattggac agccaaaact cagcacacat cccttccttt gtccaaagcc ccagaaaatg aacacttgct tggggcagca tctaaccctg aggaaccatg gaggaattca ctccggtgta tatccgaaat gaataggctg ttttctggaa aaggagacat aaccaagcca gggtacgatc cctgcaatct attggttgac ctggatgaca tcagagacct gtcttctggg ttcagcaaat acctagactt catccgttac ctgcccatcc acctctccaa gtacattcta agtatgctgg ggtgtatgag gggatttccc agacacctcc catcttggcc cagttctggg gtttctgggt ccatcttttt ttttccagga atgctggata gacacaccct gaacaagtgc gcctctgtga gccagcactg ggccgccatg gctcaacagg tcaagatgga cttgtcagcg cacggcttca ttcagaacca gattaccttc ttgcaggggt cctacacaag aggaattgat cctaattatg ccaataaggt ttctatccca gttcctaaaa tggtagatga cgggaagagc atgcgtgtga aacatccgaa gtggaagctg agaacgaaga atgagtacaa cctgtggact gcataccaga acgaggaaac gcagcaggtc ctgatagagg agagaaatgt tttctgtggg acctacaatg ttcgcattct ctctgacacg tgggatcaaa accgagtcat ccactattcc gggggagatc tgatagctgt gtcatctaat cgaaagatcc atcttctgga catcatacaa gtgaaagcga tacccgttga attccgaggc catgctggga gtgtccgggc cctcttcctg tgtgaggagg aaaactttct cctaagcggg agctatgacc taagtatcag atactgggat ctgaaaagtg gggtttgcac acgaatcttc ggtggtcacc aggggactat cacttgcatg gacttgtgta agaacaggct cgtatctgga ggaagagatt gccaggtaaa agtatgggat gtagacacag ggaagtgcct gaagacgttt agacacaaag accccatctt ggccaccagg atcaatgata cctacattgt gagcagctgt gagcgagggc tggtgaaagt gtggcacatt gccatggccc agttggtaaa gactctcagt ggccatgagg gagccgtgaa atgcctgttc tttgaccagt ggcatctcct ctcaggaagt actgatggcc tggtcatggc ctggagcatg gtggggaagt acgagcgctg cctgatggcc ttcaagcatc ccaaggaggt gctcgacgtg tccctcctct tcctccgggt catcagcgcc tgtgcagatg gcaagatccg aatttacaat ttcctcaacg ggaactgtat gaaggtgtta aaagccaatg gcagaggtga tcctgtgctg tccttcttta ttcagggcaa caggatggtg gtcaacacag agagcaatgt tctcatgttc cagtttgagc acataaagtg gcagtatgcc gtggaaaaaa cgaaacaaaa gaagaataag gagaaagagg aggaaaaaga agaaaatagt ctcatggaaa ttctctctaa gtgtaatatt caggttcaca gcccaagaga gtctgtatcc agtaaacaaa ctgtgatcca agagctccta ccaggcaaac ctcccaagtc ccgagtactc ctgaagccgg ccaagttctc ttcagatgat gtggagaaag cacaaaaaca aggacaattg gaaactcctg gaaaactgcc cagtcaccca aagaaaaagt cttggaaaat ccctatgtca cctgaccaat tcctcctgac tgttagcgcc ctgcagcacg cccataattc cggggaattt gcctatccct gtaggcccca aacagaaatt actgatgtct ggggaccttc aatttcatac ccaaggaagg tcttgaattt caaaggaaaa tcaatccaac gtgcagttga tcggttgaga ttgagcaatc ctcctataga tgtgaaacga accagtattc cccttgaaat ccagaaactg cagcccaact tgaagatctc tttgcacagt cctagagtcc agtccaccat accccagccc atgattatcc gctccaggtt ctctggcagc ttaaagggtg gagaccaagt gaccagttca attgaaaggg ctgtgtgcag tacgggtccc ctgaccagta tgcaggtcat taaaccaaac cgcatgctag ctccacaagt gggcacagcc accctgtctc ttaagaaaga acggcctcgc atctatacag cccttgatcc ttttagagtg aacactgagt tcgtgctgtt gaccgtgaag gaggagaagg agcaccagga agccaagatg aaggaatatc aggccaggga gtccactgga gtggttgatc caggaaaagt cagcaaagct gcatggatca ggaagatcaa aggcctgcct attgataatt tcacgaagca agggaaaaca gcggcccctg aacttggaca aaatgtattt atctaa. It is sometimes possible for the material contained within the vial of "FBXW10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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