FAAH cdna clone
FAAH cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide. [provided by RefSeq, Jul 2008]
Uniprot Description
FAAH: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. Homodimer. Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. Inhibited by O-aryl carbamates and alpha-keto heterocytes. Belongs to the amidase family.
Protein type: Membrane protein, integral; EC 3.5.1.99; Hydrolase
Chromosomal Location of Human Ortholog: 1p35-p34
Cellular Component: endoplasmic reticulum membrane
Molecular Function: fatty acid amide hydrolase activity; protein binding
Biological Process: arachidonic acid metabolic process; fatty acid catabolic process
Disease: Polysubstance Abuse, Susceptibility To
Research Articles on FAAH
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Product Notes
The FAAH faah (Catalog #AAA1273414) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGTGCAGT ACGAGCTGTG GGCCGCGCTG CCTGGCGCCT CCGGGGTCGC CCTGGCCTGC TGCTTCGTGG CGGCGGCCGT GGCCCTGCGC TGGTCCGGGC GCCGGACGGC GCGGGGCGCG GTGGTCCGGG CGCGACAGAG GCAGCGAGCG GGCCTGGAGA ACATGGACAG GGCGGCGCAG CGCTTCCGGC TCCAGAACCC AGACCTGGAC TCAGAGGCGC TGCTAGCCCT GCCCCTGCCT CAGCTGGTGC AGAAGTTACA CAGTAGAGAG CTGGCCCCTG AGGCCGTGCT CTTCACCTAT GTGGGAAAGG CCTGGGAAGT GAACAAAGGG ACCAACTGTG TGACCTCCTA TCTGGCTGAC TGTGAGACTC AGCTGTCTCA GGCCCCAAGG CAGGGCCTGC TCTATGGCGT CCCTGTGAGC CTCAAGGAGT GCTTCACCTA CAAGGGCCAG GACTCCACGC TGGGCTTGAG CCTGAATGAA GGGGTGCCGG CGGAGTGCGA CAGCGTAGTG GTGCATGTGC TGAAGCTGCA GGGTGCCGTG CCCTTCGTGC ACACCAATGT TCCACAGTCC ATGTTCAGCT ATGACTGCAG TAACCCCCTC TTTGGCCAGA CCGTGAACCC ATGGAAGTCC TCCAAAAGCC CAGGGGGCTC CTCAGGGGGT GAAGGGGCCC TCATCGGGTC TGGAGGCTCC CCCCTGGGCT TAGGCACTGA TATCGGAGGC AGCATCCGCT TCCCCTCCTC CTTCTGCGGC ATCTGCGGCC TCAAGCCCAC AGGGAACCGC CTCAGCAAGA GTGGCCTGAA GGGCTGTGTC TATGGACAGG AGGCAGTGCG TCTCTCCGTG GGCCCCATGG CCCGGGACGT GGAGAGCCTG GCACTGTGCC TGCGAGCCCT GCTGTGCGAG GACATGTTCC GCTTGGACCC CACTGTGCCT CCCTTGCCCT TCAGAGAAGA GGTCTACACC AGCTCTCAGC CCCTGCGTGT GGGGTACTAT GAGACTGACA ACTATACCAT GCCCTCCCCG GCCATGAGGC GGGCCGTGCT GGAGACCAAA CAGAGCCTTG AGGCTGCGGG GCACACGCTG GTTCCCTTCT TGCCAAGCAA CATACCCCAT GCTCTGGAGA CCCTGTCAAC AGGTGGGCTC TTCAGTGATG GTGGCCACAC CTTCCTACAG AACTTCAAAG GTGATTTCGT GGACCCCTGC CTGGGGGACC TGGTCTCAAT TCTGAAGCTT CCCCAATGGC TTAAAGGACT GCTGGCCTTC CTGGTGAAGC CTCTGCTGCC AAGGCTGTCA GCTTTCCTCA GCAACATGAA GTCTCGTTCG GCTGGAAAAC TCTGGGAACT GCAGCACGAG ATCGAGGTGT ACCGCAAAAC CGTGATTGCC CAGTGGAGGG CGCTGGACCT GGATGTGGTG CTGACCCCCA TGCTGGCCCC TGCTCTGGAC TTGAATGCCC CAGGCAGGGC CACAGGGGCC GTCAGCTACA CTATGCTGTA CAACTGCCTG GACTTCCCTG CAGGGGTGGT GCCTGTCACC ACGGTGACTG CTGAGGACGA GGCCCAGATG GAACATTACA GGGGCTACTT TGGGGATATC TGGGACAAGA TGCTGCAGAA GGGCATGAAG AAGAGTGTGG GGCTGCCGGT GGCCGTGCAG TGTGTGGCTC TGCCCTGGCA AGAAGAGTTG TGTCTGCGGT TCATGCGGGA GGTGGAGCGA CTGATGACCC CTGAAAAGCA GTCATCCTGA. It is sometimes possible for the material contained within the vial of "FAAH, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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