DOCK10 cdna clone
DOCK10 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]
Uniprot Description
DOCK10: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q36.2
Cellular Component: membrane
Biological Process: regulation of cell migration
Research Articles on DOCK10
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Product Notes
The DOCK10 dock10 (Catalog #AAA1271324) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaaaaaca gcaatttccc agcagaggtg aaggacctga ctaagcgtat aaggactgtt ttgatggcca cagctcagat gaaggagcac gagaaggacc ccgagatgct ggtggatctc cagtacagcc tggcaaactc ctacgcaagc actcctgaac tacgcaggac ctggctggaa agtatggcca agattcatgc cagaaacgga gatttatctg aggctgccat gtgttacatc catattgctg ctctcattgc agagtatctg aaaagaaagg gttactggaa agtggaaaag atttgcacag catccctgct ctcggaggat acccacccct gtgatagcaa ctcattacta acaactccca gtggaggaag catgttctct atgggatggc cagctttttt gagcattaca ccaaacatta aggaagaagg agcgatgaaa gaggattctg gaatgcaaga tacaccatac aatgagaata tcctggtgga gcagctatac atgtgtgtgg agtttctctg gaagtctgag cgatatgaac tcattgctga tgtcaacaag cccatcattg ctgtctttga gaaacaacga gacttcaaaa aattgtcaga tctctactac gacattcatc ggtcatatct gaaagtggca gaggtggtga attcggagaa gcggctgttt ggtcgctact atcgtgtggc attttatggg cagggctttt ttgaagaaga agaaggtaaa gagtatattt ataaagagcc taagctgaca ggtctgtccg agatttccca aagattactc aagctctatg cagataaatt tggagcagac aatgtgaaga taatccagga ttccaacaag gtaaacccca aggatttgga ccccaaatat gcctacatcc aggtgaccta tgtgacgccg ttctttgagg aaaaggaaat cgaagaccgg aagacagatt tcgaaatgca ccacaacatc aaccgctttg tcttcgagac acccttcacg ctgtcgggca agaagcacgg tggggtggcg gagcagtgca agcggcggac gatcctgaca acgagtcacc tgttccccta cgtgaagaag agaatacaag taattagcca atcgagcaca gaactgaatc caattgaagt ggcaattgac gagatgtcca agaaggtttc tgagcttaat cagctttgca caatggaaga agtggacatg atcagactgc agctcaaact gcaaggaagt gtcagcgtga aggttaatgc tgggccaatg gcctatgcac gagcttttct tgaagaaacc aatgcaaaga agtaccctga caaccaagta aagcttttga aggagatctt caggcaattt gcagatgcat gtgggcaggc ccttgacgtg aatgagcgcc tcatcaaaga ggaccagctg gagtaccagg aagaactgag gtcccactac aaggacatgc tcagcgaact ctccacagtc atgaatgagc agattacggg cagggacgac ctgtcaaagc gcggagtgga ccaaacctgc actcgagtaa ttagcaaagc aactccggcc ctacccacgg tctccatctc atctagtgct gaagtctga. It is sometimes possible for the material contained within the vial of "DOCK10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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