DNAJC7 cdna clone

DNAJC7 cDNA Clone

Cat. Num. AAA1277162

• Gene Names: DNAJC7; DJ11; DJC7; TPR2; TTC2
• Synonyms: DNAJC7; DNAJC7 cDNA Clone; DNAJC7 cdna clone

• Sequence: atggcggctgccgcggagtgcgatgtggtaatggcggcgaccgagccggagctgctcgacgaccaagaggcgaagagggaagcagagactttcaaggaacaaggaaatgcatactatgccaagaaagattacaatgaagcttataattattatacaaaagccatagatatgtgtcctaaaaatgctagctattatggtaatcgagcagccaccttgatgatgcttggaaggttccgggaagctcttggagatgcacaacagtcagtgaggttggatgacagttttgtccggggacatctacgagagggcaagtgccacctctctctggggaatgccatggcagcatgtcgcagcttccagagagccctagaactggatcataaaaatgctcaggcacaacaagagttcaagaatgctaatgcagtcatggaatatgagaaaatagcagaaacagattttgagaagcgagattttcggaaggttgttttctgcatggaccgtgccctagaatttgcccctgcctgccatcgcttcaaaatcctcaaggcagaatgtttagcaatgctgggtcgttatccagaagcacagtctgtggctagtgacattctacgaatggattccaccaatgcagatgctctgtatgtacgaggtctttgcctttattacgaagattgtattgagaaggcagttcagtttttcgtacaggctctcaggatggctcctgaccacgagaaggcctgcattgcctgcagaaatgccaaagcactcaaagcaaagaaagaagatgggaataaagcatttaaggaaggaaattacaaactagcatatgaactgtacacagaagccctggggatagaccccaacaatataaaaacaaatgctaaactctactgtaatcggggtacggttaattccaagcttaggaaactagatgatgcaatagaagactgcacaaatgcagtgaagcttgatgacacttacataaaagcctacttgagaagagctcagtgttacatggacacagaacagtatgaagaagcagtacgagactatgaaaaagtataccagacagagaaaacaaaagaacacaaacagctcctaaaaaatgcgcagctggaactgaagaagagtaagaggaaagattactacaagattctaggagtggacaagaatgcctctgaggacgagatcaagaaagcttatcggaaacgggccttgatgcaccatccagatcggcatagtggagccagtgctgaggttcagaaggaggaggagaagaagttcaaggaagttggagaggcctttactatcctctctgatcccaagaaaaagactcgctatgacagtggacaggacctagatgaggagggcatgaatatgggtgattttgatccaaacaatatcttcaaggcattctttggcggtcctggcggcttcagctttgaagcatctggtccagggaatttcttttttcaatttggctaa
• Sequence Length: 1485

• Vector: pENTR223.1 or pUC
• Clone Sequence Report: Provided with product shipment

NCBI and Uniprot Product Information

• NCBI GI #: 40225849
• NCBI GeneID: 7266
• Molecular Weight: 50,097 Da
• NCBI Official Full Name: Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 7, mRNA
• NCBI Official Synonym Full Names: DnaJ heat shock protein family (Hsp40) member C7
• NCBI Official Symbol: DNAJC7
• NCBI Official Synonym Symbols: DJ11; DJC7; TPR2; TTC2
• NCBI Protein Information: dnaJ homolog subfamily C member 7
• UniProt Protein Name: DnaJ homolog subfamily C member 7
• Protein Family: DnaJ homolog subfamily
• UniProt Gene Name: DNAJC7
• UniProt Synonym Gene Names: TPR2; TTC2; TPR repeat protein 2
• UniProt Entry Name: DNJC7_HUMAN

NCBI Description

This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Uniprot Description

DNAJC7: a co-chaperone protein that binds both Hsp70 and Hsp90 through its TPR domains. Its DnaJ domain stimulates ATP hydrolysis and polypeptide binding by Hsp70. Interacts with the proapoptotic and cell-cycle checkpoint protein Rad9. Rad9 transiently dissociates from Tpr2 following heat-shock or UV treatments.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: cytoplasm; cytosol; membrane; nucleoplasm

Molecular Function: ATPase activator activity; heat shock protein binding; protein binding

Biological Process: protein folding