DNAJC6 cdna clone

DNAJC6 cDNA Clone

Gene Names

DNAJC6; DJC6; PARK19

Synonyms

DNAJC6; DNAJC6 cDNA Clone; DNAJC6 cdna clone

Ordering
Cat. Num. AAA1269344 For Research Use Only!

Sequence

ATGAGCCTCCTCGGGAGCTACCGGAAAAAGACCAGCAACGATGGTTATGAATCTTTGCAGCTGGTGGACAGTAACGGGGACTTAAGTGCGGGAAGCGGCGGGGTTGGCGGCAAGCAGAGAGTGAACGCCGGGGCAGCGGCGCGGAGTCCCGCCCGACAGCCTCCGGACCGCGCCAGCACCATGGACAGCTCAGGTGCCTCATCTCCAGACATGGAGCCCAGCTATGGGGGAGGTCTCTTTGACATGGTAAAAGGAGGTGCAGGGAGGCTCTTTAGTAACCTAAAGGACAACTTGAAAGACACCCTCAAAGACACATCTTCTAGAGTGATACAATCTGTGACCAGCTACACAAAGGGAGATTTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAATGTTGACATAGGATTCAGGAATCAGGTTGATGACATTCGAAGCTTTTTGGATTCCAGACATCTTGACCACTACACAGTATACAATCTGTCACCTAAGTCTTATCGAACTGCCAAGTTTCACAGCCGGGTCTCAGAATGCAGTTGGCCCATTAGGCAGGCTCCCAGTCTGCACAACCTTTTTGCTGTGTGTCGGAATATGTATAACTGGCTACTGCAGAATCCCAAAAATGTCTGTGTTGTCCACTGCTTGGATGGACGGGCGGCATCATCAATTCTGGTTGGTGCTATGTTCATTTTCTGTAATCTCTACTCTACTCCTGGCCCAGCCATTCGATTGCTATATGCAAAGCGACCAGGAATTGGACTTTCACCATCCCATAGGAGATACCTGGGCTATATGTGTGACCTACTGGCAGACAAGCCCTACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAATACCCTTTTTCAACAAACAGAGGAATGGATGTCGCCCTTACTGTGATGTACTCATTGGAGAAACCAAAATATATTCGACTTGCACAGATTTTGAACGAATGAAAGAATATCGTGTCCAAGATGGAAAAATCTTCATTCCCTTGAACATCACTGTGCAAGGAGACGTGGTTGTTTCCATGTATCACTTGAGGTCAACCATTGGGAGCCGGCTACAGGCTAAGGTGACCAACACACAGATATTCCAGCTTCAGTTTCACACTGGATTCATACCACTGGACACAACAGTTTTAAAGTTCACCAAGCCTGAGTTAGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAGGTGACACTGGATGTAGAACTACAGCCCCATGACAAAGTAATAGACTTAACTCCACCATGGGAACATTACTGCACAAAAGATGTCAATCCCAGCATCCTCTTCTCTTCTCACCAGGAACATCAAGATACGCTGGCCTTAGGAGGACAGGCTCCAATAGATATCCCTCCAGACAACCCCAGGCATTACGGACAAAGTGGTTTCTTTGCCTCTCTCTGTTGGCAAGATCAGAAATCGGAGAAGTCATTCTGTGAGGAAGACCACGCTGCCCTAGTGAATCAGGAAAGTGAGCAATCAGATGATGAACTTCTGACACTTTCCAGTCCGCATGGCAATGCCAATGGTGACAAGCCTCATGGAGTCAAGAAGCCCAGCAAAAAGCAGCAGGAGCCAGCAGCCCCTCCACCCCCTGAGGATGTGGACCTTTTGGGCCTGGAAGGGTCTGCAATGAGTAACAGCTTCTCTCCGCCAGCGGCTCCTCCCACCAATTCTGAACTACTGAGTGACCTGTTTGGGGGTGGAGGTGCAGCTGGTCCCACCCAGGCTGGACAGTCAGGAGTGGAAGATGTGTTTCATCCTAGTGGACCTGCGTCTACCCAGTCAACACCACGCCGCTCTGCCACCTCCACCTCTGCGTCTCCAACCCTAAGAGTGGGAGAAGGTGCCACCTTTGACCCATTTGGAGCACCTTCTAAACCATCAGGTCAGGATTTGCTGGGTTCTTTTCTGAACACATCCAGTGCTTCCAGTGACCCCTTTCTCCAGCCCACAAGAAGTCCTTCGCCCACAGTACATGCTTCTAGTACGCCTGCTGTGAACATTCAGCCAGATGTTTCTGGAGGTTGGGACTGGCATGCTAAACCAGGAGGCTTTGGAATGGGAAGCAAGTCAGCTGCCACCAGCCCAACCGGATCCTCGCATGGTACTCCCACCCATCAAAGCAAACCCCAGACTCTGGATCCTTTTGCCGACCTTGGGACACTAGGTAGTTCTTCCTTTGCCAGCAAACCCACCACACCAACTGGATTGGGTGGAGGATTCCCGCCTCTCAGCTCGCCACAGAAGGCGTCTCCCCAGCCTATGGGTGGCGGGTGGCAGCAGGGAGGTGCCTACAACTGGCAGCAGCCACAGCCTAAGCCTCAGCCCAGCATGCCCCACTCCTCTCCCCAGAACCGACCCAACTACAACGTGAGCTTCTCAGCCATGCCTGGGGGCCAGAACGAACGTGGGAAAGGATCAAGTAATTTGGAAGGGAAACAAAAAGCAGCTGATTTTGAAGACCTACTCTCTGGTCAAGGTTTCAATGCTCACAAAGACAAAAAGGGGCCTCGGACAATAGCTGAGATGAGAAAGGAGGAAATGGCCAAGGAAATGGATCCTGAGAAATTAAAGATTCTGGAATGGATTGAAGGCAAAGAAAGAAATATCAGAGCCCTTCTTTCCACGATGCATACCGTACTATGGGCTGGGGAGACCAAGTGGAAACCAGTTGGCATGGCAGACCTGGTAACACCAGAGCAGGTGAAGAAGGTGTACAGGAAGGCTGTCCTGGTGGTGCACCCAGATAAAGCTACTGGGCAACCCTATGAACAATACGCAAAGATGATTTTCATGGAGCTCAATGATGCCTGGTCTGAATTTGAAAACCAAGGCCAAAAGCCCTTATATTAA

Sequence Length

2913

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #

115527442

NCBI GeneID

9829

Molecular Weight

98,649 Da

NCBI Official Full Name

Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 6, mRNA

NCBI Official Synonym Full Names

DnaJ heat shock protein family (Hsp40) member C6

NCBI Official Symbol

DNAJC6

NCBI Official Synonym Symbols

DJC6; PARK19

NCBI Protein Information

putative tyrosine-protein phosphatase auxilin

UniProt Protein Name

Putative tyrosine-protein phosphatase auxilin

Protein Family

Putative tyrosine-protein phosphatase auxilin

UniProt Gene Name

DNAJC6

UniProt Synonym Gene Names

KIAA0473

UniProt Entry Name

AUXI_HUMAN

NCBI Description

DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008]

Uniprot Description

DNAJC6: Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Chaperone; Protein phosphatase, tyrosine (non-receptor); EC 3.1.3.48

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cytosol; vesicle

Biological Process: receptor-mediated endocytosis

Disease: Parkinson Disease 19, Juvenile-onset

Research Articles on DNAJC6

1. DNAJC6 mutations are associated with early-onset Parkinson's disease.

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Product Notes

The DNAJC6 dnajc6 (Catalog #AAA1269344) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGCCTCC TCGGGAGCTA CCGGAAAAAG ACCAGCAACG ATGGTTATGA ATCTTTGCAG CTGGTGGACA GTAACGGGGA CTTAAGTGCG GGAAGCGGCG GGGTTGGCGG CAAGCAGAGA GTGAACGCCG GGGCAGCGGC GCGGAGTCCC GCCCGACAGC CTCCGGACCG CGCCAGCACC ATGGACAGCT CAGGTGCCTC ATCTCCAGAC ATGGAGCCCA GCTATGGGGG AGGTCTCTTT GACATGGTAA AAGGAGGTGC AGGGAGGCTC TTTAGTAACC TAAAGGACAA CTTGAAAGAC ACCCTCAAAG ACACATCTTC TAGAGTGATA CAATCTGTGA CCAGCTACAC AAAGGGAGAT TTAGACTTCA CTTATGTTAC CTCCAGAATT ATTGTGATGT CCTTTCCTCT GGACAATGTT GACATAGGAT TCAGGAATCA GGTTGATGAC ATTCGAAGCT TTTTGGATTC CAGACATCTT GACCACTACA CAGTATACAA TCTGTCACCT AAGTCTTATC GAACTGCCAA GTTTCACAGC CGGGTCTCAG AATGCAGTTG GCCCATTAGG CAGGCTCCCA GTCTGCACAA CCTTTTTGCT GTGTGTCGGA ATATGTATAA CTGGCTACTG CAGAATCCCA AAAATGTCTG TGTTGTCCAC TGCTTGGATG GACGGGCGGC ATCATCAATT CTGGTTGGTG CTATGTTCAT TTTCTGTAAT CTCTACTCTA CTCCTGGCCC AGCCATTCGA TTGCTATATG CAAAGCGACC AGGAATTGGA CTTTCACCAT CCCATAGGAG ATACCTGGGC TATATGTGTG ACCTACTGGC AGACAAGCCC TACCGCCCTC ACTTCAAGCC TCTCACAATT AAGTCGATCA CTGTCAGTCC AATACCCTTT TTCAACAAAC AGAGGAATGG ATGTCGCCCT TACTGTGATG TACTCATTGG AGAAACCAAA ATATATTCGA CTTGCACAGA TTTTGAACGA ATGAAAGAAT ATCGTGTCCA AGATGGAAAA ATCTTCATTC CCTTGAACAT CACTGTGCAA GGAGACGTGG TTGTTTCCAT GTATCACTTG AGGTCAACCA TTGGGAGCCG GCTACAGGCT AAGGTGACCA ACACACAGAT ATTCCAGCTT CAGTTTCACA CTGGATTCAT ACCACTGGAC ACAACAGTTT TAAAGTTCAC CAAGCCTGAG TTAGATGCAT GTGATGTACC AGAAAAATAT CCTCAGCTAT TTCAGGTGAC ACTGGATGTA GAACTACAGC CCCATGACAA AGTAATAGAC TTAACTCCAC CATGGGAACA TTACTGCACA AAAGATGTCA ATCCCAGCAT CCTCTTCTCT TCTCACCAGG AACATCAAGA TACGCTGGCC TTAGGAGGAC AGGCTCCAAT AGATATCCCT CCAGACAACC CCAGGCATTA CGGACAAAGT GGTTTCTTTG CCTCTCTCTG TTGGCAAGAT CAGAAATCGG AGAAGTCATT CTGTGAGGAA GACCACGCTG CCCTAGTGAA TCAGGAAAGT GAGCAATCAG ATGATGAACT TCTGACACTT TCCAGTCCGC ATGGCAATGC CAATGGTGAC AAGCCTCATG GAGTCAAGAA GCCCAGCAAA AAGCAGCAGG AGCCAGCAGC CCCTCCACCC CCTGAGGATG TGGACCTTTT GGGCCTGGAA GGGTCTGCAA TGAGTAACAG CTTCTCTCCG CCAGCGGCTC CTCCCACCAA TTCTGAACTA CTGAGTGACC TGTTTGGGGG TGGAGGTGCA GCTGGTCCCA CCCAGGCTGG ACAGTCAGGA GTGGAAGATG TGTTTCATCC TAGTGGACCT GCGTCTACCC AGTCAACACC ACGCCGCTCT GCCACCTCCA CCTCTGCGTC TCCAACCCTA AGAGTGGGAG AAGGTGCCAC CTTTGACCCA TTTGGAGCAC CTTCTAAACC ATCAGGTCAG GATTTGCTGG GTTCTTTTCT GAACACATCC AGTGCTTCCA GTGACCCCTT TCTCCAGCCC ACAAGAAGTC CTTCGCCCAC AGTACATGCT TCTAGTACGC CTGCTGTGAA CATTCAGCCA GATGTTTCTG GAGGTTGGGA CTGGCATGCT AAACCAGGAG GCTTTGGAAT GGGAAGCAAG TCAGCTGCCA CCAGCCCAAC CGGATCCTCG CATGGTACTC CCACCCATCA AAGCAAACCC CAGACTCTGG ATCCTTTTGC CGACCTTGGG ACACTAGGTA GTTCTTCCTT TGCCAGCAAA CCCACCACAC CAACTGGATT GGGTGGAGGA TTCCCGCCTC TCAGCTCGCC ACAGAAGGCG TCTCCCCAGC CTATGGGTGG CGGGTGGCAG CAGGGAGGTG CCTACAACTG GCAGCAGCCA CAGCCTAAGC CTCAGCCCAG CATGCCCCAC TCCTCTCCCC AGAACCGACC CAACTACAAC GTGAGCTTCT CAGCCATGCC TGGGGGCCAG AACGAACGTG GGAAAGGATC AAGTAATTTG GAAGGGAAAC AAAAAGCAGC TGATTTTGAA GACCTACTCT CTGGTCAAGG TTTCAATGCT CACAAAGACA AAAAGGGGCC TCGGACAATA GCTGAGATGA GAAAGGAGGA AATGGCCAAG GAAATGGATC CTGAGAAATT AAAGATTCTG GAATGGATTG AAGGCAAAGA AAGAAATATC AGAGCCCTTC TTTCCACGAT GCATACCGTA CTATGGGCTG GGGAGACCAA GTGGAAACCA GTTGGCATGG CAGACCTGGT AACACCAGAG CAGGTGAAGA AGGTGTACAG GAAGGCTGTC CTGGTGGTGC ACCCAGATAA AGCTACTGGG CAACCCTATG AACAATACGC AAAGATGATT TTCATGGAGC TCAATGATGC CTGGTCTGAA TTTGAAAACC AAGGCCAAAA GCCCTTATAT TAA. It is sometimes possible for the material contained within the vial of "DNAJC6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

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DNAJC6 cdna clone