DNAJB4 cdna clone
DNAJB4 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Uniprot Description
DNAJB4: Probable chaperone. Homodimer. The C-terminal section interacts with the C- terminal tail of OPRM1. Interacts also with SDIM1. By heat shock. Expressed in heart, pancreas and skeletal muscle, and to a lesser extent in brain, placenta and liver.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 1p31.1
Cellular Component: cytoplasm; cytosol; nucleoplasm; plasma membrane
Molecular Function: chaperone binding; protein binding
Biological Process: response to heat; response to unfolded protein
Research Articles on DNAJB4
Similar Products
Product Notes
The DNAJB4 dnajb4 (Catalog #AAA1278642) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggggaaag actattattg cattttggga attgagaaag gagcttcaga tgaagatatt aaaaaggctt accgaaaaca agccctcaaa tttcatccgg acaagaacaa atctcctcag gcagaggaaa aatttaaaga ggtcgcagaa gcttatgaag tattgagtga tcctaaaaag agagaaatat atgatcagtt tggggaggaa gggttgaaag gaggagcagg aggtactgat ggacaaggag gtaccttccg gtacaccttt catggcgatc ctcatgctac atttgctgca tttttcggag ggtccaaccc ctttgaaatt ttctttggaa gacgaatggg tggtggtaga gattctgaag aaatggaaat agatggtgat ccttttagtg cctttggttt cagcatgaat ggatatccaa gagacaggaa ttctgtgggg ccatcccgcc tcaaacaaga tcctccagtt attcatgaac ttagagtatc acttgaagag atatatagtg gttgtaccaa acggatgaag atttctcgaa aaaggctaaa cgctgatgga aggagttaca gatctgagga caaaattctt accattgaga ttaaaaaagg gtggaaagaa ggcaccaaaa ttacttttcc aagagaagga gatgaaacac caaatagtat tccagcagac attgttttta tcattaaaga caaagatcat ccaaaattta aaagggatgg atcaaatata atttatactg ctaaaattag tttacgagag gcattgtgtg gctgctcaat taatgtacca acactggatg gaagaaacat acctatgtca gtaaatgata ttgtgaaacc cggaatgagg agaagaatta ttggatatgg gctgccattt ccaaaaaatc ctgaccaacg tggtgacctt ctaatagaat ttgaggtgtc cttcccagat actatatctt cttcatccaa agaagtactt aggaaacatc ttcctgcctc atag. It is sometimes possible for the material contained within the vial of "DNAJB4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
