DIAPH2 cdna clone
DIAPH2 cDNA Clone
Gene Names
DIAPH2; DIA; POF; DIA2; DRF2; POF2
Synonyms
DIAPH2; DIAPH2 cDNA Clone; DIAPH2 cdna clone
Sequence
atggagcagcccggggcggcggcgtcgggagcgggaggcggcagcgaggaacccggtgggggccggagcaacaagcggagcgcggggaaccgggccgccaatgaagaggaaacgaaaaacaaacccaaattgaacattcaaataaaaactttggcagatgatgtgcgtgaccgaattacaagttttagaaaatctactgtcaaaaaagaaaaacctcttattcaacatcctattgattctcaagtcgcgatgagtgagtttcctgcagctcagccattatatgatgaacgatctttgaatttgtcagaaaaggaagtattggatctctttgaaaaaatgatggaggacatgaaccttaacgaagagaaaaaagctcctttacgaaacaaagactttaccaccaaacgtgagatggttgtccagtatatttctgccactgccaaatctatagttggaagtaaagttacgggtgggctgaaaaacagcaaacatgaatgcaccctgtcttcacaagaatatgttcatgaattacgatcgggtatatcagatgagaaacttcttaattgcctagaatccctcagggtttctttaaccagcaatccggtcagctgggttaacaactttggccatgaaggtcttggactcttattggatgagctggaaaagcttctggacaaaaaacagcaagaaaatattgacaagaagaatcagtataaacttattcaatgcctcaaagcatttatgaataataagtttggattacaaaggattctaggagatgaaagaagtcttttactattggcaagagcaattgaccccaaacaacccaacatgatgactgaaatagtaaaaatactttctgctatttgcattgttggagaagagaacattctagataaacttttaggggctataacaacagcagcagaaagaaataacagggaacgattttcaccaattgtggaaggtttagaaaatcaggaagccttgcaattacaggtggcctgcatgcagtttataaatgcccttgtcacttctccttatgagcttgattttcgaatacatttaaggaatgaattcctccgttcaggactaaaaacaatgttaccagatctaaaagaaaaagagaatgatgagcttgatattcagttgaaagtatttgatgaaaacaaagaagatgacctaactgaattatcacaccgtctcaatgacattcgagcagaaatggatgatatgaatgaagtctaccatcttctatataatatgctgaaggacactgctgctgaaaattacttcttatctattctacaacattttttgcttatcagaaatgattattatatcaggccacaatattataaaataattgaggaatgtgtttcacagatagtgctacactgcagtggtatggatccagacttcaaatacaggcaaagattagacatcgatttaactcatctgatagattcttgtgtgaacaaggcgaaagttgaagaaagtgaacaaaaagctgcagagttttcaaagaagttcgatgaagaattcacagctcgacaggaagctcaagcagagcttcaaaaaagagatgagaaaatcaaagaacttgaagcagaaatccagcaacttcgaacccaggcacaagtactctcaagttcatcaggaattccaggtcctcctgcagcacctccattgccaggtgtagggccgcctccaccaccacccgcgccacctctacccggaggagctcctcttcctcctccaccacctcctttacctggaatgatggggataccaccaccacccccaccaccacttttatttgggggacctcctccaccaccaccccttggaggagttcctcctcccccaggaatatcacttaatctaccttatggaatgaagcagaaaaaaatgtataaacctgaagtgtccatgaagagaatcaattggtcaaagattgaacccacagaattatctgagaactgtttctggttaagagtcaaagaagacaagtttgagaatccagatctctttgccaaattggcattgaattttgctactcagataaaagttcaaaagaacgcagaagcattagaagaaaagaagactgggcctacaaagaagaaagtgaaagaactgagaattttggatcccaaaacagctcagaatctgtccatctttctgggatcatatcgcatgccatatgaagacataagaaacgttattctggaggttaatgaagacatgctgagtgaggctttaattcagaaccttgtgaaacatcttcctgagcagaagatactcaacgaattagcagagcttaagaatgaatatgatgacctctgtgagcctgaacaatttggagttgtgatgagctctgtgaaaatgttacagcctcgtctcagtagtatcctgttcaagctcacatttgaagaacacataaacaacatcaaaccaagcatcatagcagtaactcttgcctgtgaagaactgaagaaaagtgaaagctttaacagacttttagagttagttcttcttgttggaaactacatgaactcaggctcaagaaatgcccagtctttgggatttaagatcaacttcctttgtaagatcagagatactaaatcagcggatcaaaaaacaacccttttgcattttattgccgacatttgtgaggaaaaatatcgagatatcctaaaatttcctgaagaactggaacacgtagaaagtgcaagcaaagtttcagctcaaattctcaagagcaaccttgcatcaatggaacaacaaattgttcatctggaacgtgacatcaagaaattcccccaagcagaaaatcaacacgataagtttgtggaaaagatgaccagctttacaaagactgcccgagaacagtatgaaaaactctccaccatgcacaacaacatgatgaagctctatgagaatcttggagaatacttcatttttgactcaaagacagtgagcatagaagagttctttggtgatctcaacaacttccgaactttgtttttggaagcagtgagagaaaacaataagagaagagaaatggaagagaagaccaggagggcaaaacttgcaaaagagaaagctgaacaagaaaagttagaacgccagaagaaaaagaaacaactcattgatataaacaaagagggtgatgagactggtgtgatggataatcttctagaagccctacaatcaggtgcagcattcagagaccgtcgaaagcggattccaaggaatccagtggtaaatcatccctgtgcaacaagggctaatccaagatcagctacataa
Sequence Length
3312
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
125,043 Da
NCBI Official Full Name
Homo sapiens diaphanous homolog 2 (Drosophila), mRNA
NCBI Official Synonym Full Names
diaphanous related formin 2
NCBI Official Symbol
DIAPH2
NCBI Official Synonym Symbols
DIA; POF; DIA2; DRF2; POF2
NCBI Protein Information
protein diaphanous homolog 2
UniProt Protein Name
Protein diaphanous homolog 2
Protein Family
UniProt Gene Name
DIAPH2
UniProt Synonym Gene Names
DIA; DRF2
UniProt Entry Name
DIAP2_HUMAN
NCBI Description
The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
Diaphanous-2: Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. Isoform 3 interacts with RHOD in the GTP-bound form. Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes. Belongs to the formin homology family. Diaphanous subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: Xq21.33
Cellular Component: cytosol; Golgi apparatus; intracellular membrane-bound organelle; mitochondrion; nucleolus
Molecular Function: receptor binding
Biological Process: cytokinesis; female gamete generation
Disease: Premature Ovarian Failure 2a
Research Articles on DIAPH2
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Product Notes
The DIAPH2 diaph2 (Catalog #AAA1273323) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagcagc ccggggcggc ggcgtcggga gcgggaggcg gcagcgagga acccggtggg ggccggagca acaagcggag cgcggggaac cgggccgcca atgaagagga aacgaaaaac aaacccaaat tgaacattca aataaaaact ttggcagatg atgtgcgtga ccgaattaca agttttagaa aatctactgt caaaaaagaa aaacctctta ttcaacatcc tattgattct caagtcgcga tgagtgagtt tcctgcagct cagccattat atgatgaacg atctttgaat ttgtcagaaa aggaagtatt ggatctcttt gaaaaaatga tggaggacat gaaccttaac gaagagaaaa aagctccttt acgaaacaaa gactttacca ccaaacgtga gatggttgtc cagtatattt ctgccactgc caaatctata gttggaagta aagttacggg tgggctgaaa aacagcaaac atgaatgcac cctgtcttca caagaatatg ttcatgaatt acgatcgggt atatcagatg agaaacttct taattgccta gaatccctca gggtttcttt aaccagcaat ccggtcagct gggttaacaa ctttggccat gaaggtcttg gactcttatt ggatgagctg gaaaagcttc tggacaaaaa acagcaagaa aatattgaca agaagaatca gtataaactt attcaatgcc tcaaagcatt tatgaataat aagtttggat tacaaaggat tctaggagat gaaagaagtc ttttactatt ggcaagagca attgacccca aacaacccaa catgatgact gaaatagtaa aaatactttc tgctatttgc attgttggag aagagaacat tctagataaa cttttagggg ctataacaac agcagcagaa agaaataaca gggaacgatt ttcaccaatt gtggaaggtt tagaaaatca ggaagccttg caattacagg tggcctgcat gcagtttata aatgcccttg tcacttctcc ttatgagctt gattttcgaa tacatttaag gaatgaattc ctccgttcag gactaaaaac aatgttacca gatctaaaag aaaaagagaa tgatgagctt gatattcagt tgaaagtatt tgatgaaaac aaagaagatg acctaactga attatcacac cgtctcaatg acattcgagc agaaatggat gatatgaatg aagtctacca tcttctatat aatatgctga aggacactgc tgctgaaaat tacttcttat ctattctaca acattttttg cttatcagaa atgattatta tatcaggcca caatattata aaataattga ggaatgtgtt tcacagatag tgctacactg cagtggtatg gatccagact tcaaatacag gcaaagatta gacatcgatt taactcatct gatagattct tgtgtgaaca aggcgaaagt tgaagaaagt gaacaaaaag ctgcagagtt ttcaaagaag ttcgatgaag aattcacagc tcgacaggaa gctcaagcag agcttcaaaa aagagatgag aaaatcaaag aacttgaagc agaaatccag caacttcgaa cccaggcaca agtactctca agttcatcag gaattccagg tcctcctgca gcacctccat tgccaggtgt agggccgcct ccaccaccac ccgcgccacc tctacccgga ggagctcctc ttcctcctcc accacctcct ttacctggaa tgatggggat accaccacca cccccaccac cacttttatt tgggggacct cctccaccac caccccttgg aggagttcct cctcccccag gaatatcact taatctacct tatggaatga agcagaaaaa aatgtataaa cctgaagtgt ccatgaagag aatcaattgg tcaaagattg aacccacaga attatctgag aactgtttct ggttaagagt caaagaagac aagtttgaga atccagatct ctttgccaaa ttggcattga attttgctac tcagataaaa gttcaaaaga acgcagaagc attagaagaa aagaagactg ggcctacaaa gaagaaagtg aaagaactga gaattttgga tcccaaaaca gctcagaatc tgtccatctt tctgggatca tatcgcatgc catatgaaga cataagaaac gttattctgg aggttaatga agacatgctg agtgaggctt taattcagaa ccttgtgaaa catcttcctg agcagaagat actcaacgaa ttagcagagc ttaagaatga atatgatgac ctctgtgagc ctgaacaatt tggagttgtg atgagctctg tgaaaatgtt acagcctcgt ctcagtagta tcctgttcaa gctcacattt gaagaacaca taaacaacat caaaccaagc atcatagcag taactcttgc ctgtgaagaa ctgaagaaaa gtgaaagctt taacagactt ttagagttag ttcttcttgt tggaaactac atgaactcag gctcaagaaa tgcccagtct ttgggattta agatcaactt cctttgtaag atcagagata ctaaatcagc ggatcaaaaa acaacccttt tgcattttat tgccgacatt tgtgaggaaa aatatcgaga tatcctaaaa tttcctgaag aactggaaca cgtagaaagt gcaagcaaag tttcagctca aattctcaag agcaaccttg catcaatgga acaacaaatt gttcatctgg aacgtgacat caagaaattc ccccaagcag aaaatcaaca cgataagttt gtggaaaaga tgaccagctt tacaaagact gcccgagaac agtatgaaaa actctccacc atgcacaaca acatgatgaa gctctatgag aatcttggag aatacttcat ttttgactca aagacagtga gcatagaaga gttctttggt gatctcaaca acttccgaac tttgtttttg gaagcagtga gagaaaacaa taagagaaga gaaatggaag agaagaccag gagggcaaaa cttgcaaaag agaaagctga acaagaaaag ttagaacgcc agaagaaaaa gaaacaactc attgatataa acaaagaggg tgatgagact ggtgtgatgg ataatcttct agaagcccta caatcaggtg cagcattcag agaccgtcga aagcggattc caaggaatcc agtggtaaat catccctgtg caacaagggc taatccaaga tcagctacat aa. It is sometimes possible for the material contained within the vial of "DIAPH2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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