DDX46 cdna clone
DDX46 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]
Uniprot Description
DDX46: Plays an essential role in splicing, either prior to, or during splicing A complex formation. Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
Protein type: Spliceosome; EC 3.6.4.13; Helicase
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: nucleus
Molecular Function: ATP-dependent RNA helicase activity
Biological Process: nuclear mRNA splicing, via spliceosome; regulation of gene expression; RNA secondary structure unwinding
Research Articles on DDX46
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Product Notes
The DDX46 ddx46 (Catalog #AAA1272000) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggtcggg agtcacgcca ctatcgaaaa cgatcggcat cccggggtcg ctctggaagt cggtctagaa gtcgctcacc ctcagacaaa agaagtaaac gtggagatga cagacggtct agaagtagag atagagatag gaggagagag aggtctcgta gcagggataa aagaagatct cggtcaaggg acaggaagcg tctgagacgt tccagaagta gagagagaga cagaagccga gagcgaagaa gatctcgaag tagagacagg agacgctcaa ggagtagaag ccggggccgg cgatcccgat cctccagtcc tggaaataaa agcaagaaaa ctgagaatag atctaggtcc aaagagaaaa ctgatggtgg ggaaagttct aaagagaaga aaaaagacaa agatgacaag gaggatgaaa aagaaaaaga tgctggcaac tttgaccaga ataagctgga agaagaaatg agaaagcgaa aagaaagagt agaaaaatgg cgagaagagc aacgtaaaaa ggctatggaa aacataggag aactgaaaaa ggaaatcgaa gagatgaaac aagggaaaaa gtggagttta gaggacgatg atgatgacga agatgatcct gcagaagctg aaaaggaggg aaatgaaatg gagggtgagg agttagatcc attagatgct tacatggaag aagtgaaaga ggaagtaaaa aaatttaaca tgagaagtgt aaaaggtggt gggggaaatg aaaagaagtc tgggccaacg gtcacaaaag ttgtcactgt tgtgacaacc aaaaaagcag ttgtggattc tgataagaag aaaggtgagc tgatggagaa tgaccaggat gccatggagt attcttcaga ggaggaagaa gttgatcttc agacagccct tacagggtat caaacaaaac agcgaaagct tctagaacca gttgatcatg gaaaaattga gtatgagcca tttaggaaaa acttctatgt tgaagttcca gaactagcaa aaatgtctca agaagaggta aatgtgtttc gattggaaat ggagggcatt acagttaaag gaaaaggttg ccccaaacca attaaatcct gggtccagtg tggaatttcc atgaagatct taaattccct caagaagcat ggctatgaaa agcccacgcc catccaaacc caagctattc ctgctataat gtctggacga gatttgattg gcattgccaa aacaggaagt ggaaagacca ttgcttttct gttgcccatg tttagacaca tcatggatca gaggtcatta gaggaaggag aggggccaat agctgtcatc atgactccaa ctcgagaact ggctttacag attactaaag agtgtaagaa gttttccaag actttgggac ttagagtggt ctgtgtttac ggaggaacag gaatcagtga gcagattgct gagctgaaaa gaggtgctga aattattgtt tgcacacctg gtcgaatgat tgacatgtta gccgctaaca gtggtcgggt cacaaatctt cgaagagtga catatgttgt tttagatgaa gcagacagaa tgtttgacat gggttttgaa ccccaggtca tgcgcatcgt ggataatgtt cgtcctgatc gacagacggt tatgttttca gctactttcc ccagagctat ggaggctttg gctcgcagga tcctcagtaa acctattgaa gtacaagttg gaggcaggag tgtggtttgc tcagatgtgg agcaacaagt gattgtgatt gaagaagaaa agaaattctt gaagttactt gagcttctag gccattatca agagtcagga tctgtcatta tatttgtgga taagcaggaa catgctgatg gtcttcttaa ggatttaatg agagcatctt atccttgcat gtctcttcat ggaggcattg atcaatatga cagagatagc atcataaatg actttaagaa tgggacctgc aaacttcttg tggctacctc tgttgctgcc cgaggtctag atgtgaaaca tctgattctt gtagtaaatt atagctgccc caaccattat gaggattatg tacacagagc agggcggact ggaagagcag gaaacaaggg ttatgcttat acttttatca cagaggatca agctcgctat gctggtgaca taattaaagc tcttgaattg tcagggactg cagtacctcc tgatttagag aaactgtgga gtgatttcaa agatcagcag aaagctgagg ggaaaataat taaaaagagt agtgggttct ctggtaaggg attcaagttt gatgaaacag aacaagcttt ggctaatgag aggaagaagt tacaaaaagc agctcttggt ctacaagatt cagatgatga ggatgctgca gttgatattg atgagcaaat tgaaagcatg tttaattcaa agaagagagt aaaggatatg gctgctcctg gaacatcaag tgttcctgct ccaactgcag gaaatgctga gaaattagaa attgctaaga gattggctct tagaatcaat gcccagaaga atttgggcat cgagtctcag gatgtgatgc agcaggccac caatgcaatt cttaggggtg gcaccattct ggctcccact gtttctgcaa aaaccattgc agaacaactt gctgaaaaga tcaatgccaa gctcaattat gtgccgttag agaaacaaga agaagagaga caggatggtg gacagaatga atcttttaag agatatgaag aagaattaga gatcaatgac ttcccacaga ctgctaggtg gaaagttacc tctaaggaag ctctgcagag aatcagtgaa tactctgaag ccgcaattac aatcagagga acctacttcc ctcctggcaa agaacccaag gaaggcgagc ggaagattta cttggcaatt gaaagtgcca atgaactggc tgtgcagaaa gcaaaggcag aaatcaccag gctcataaaa gaagagctga tccggctgca aaattcatac caaccaacaa ataaaggaag atacaaagtc ttatag. It is sometimes possible for the material contained within the vial of "DDX46, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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